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1.
Hum Factors ; 63(6): 999-1011, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-31603695

RESUMO

OBJECTIVE: To assess versions of the shorter form variant of Usability Metric for User Experience (UMUX-LITE) questionnaire differing in the number of response options for the items (3, 5, 7, and 11). BACKGROUND: The UMUX-LITE is an efficient (two-item) standardized questionnaire that measures perceived usability. A growing body of evidence shows it closely corresponds to one of the most widely used standardized usability questionnaires, the System Usability Scale (SUS), with regard to both correlation and magnitude of concurrently collected means. Although the "standard" version of the UMUX-LITE uses items with seven response options, there is some variance in practice. METHOD: Members of a corporate user experience panel (n = 242) completed surveys rating a recent Web site experience with the SUS and UMUX-LITE, also providing ratings of overall experience and likelihood-to-recommend. RESULTS: Scale reliabilities were acceptable (coefficient α >.70) with the exception of UMUX-LITE with three response options. All UMUX-LITE correlations with SUS, overall experience, and likelihood-to-recommend were highly significant. For likelihood-to-recommend, there was a significant difference in the magnitude of correlations, with 11 response options higher than three. Although some statistically significant differences were observed in correspondence between SUS and UMUX-LITE scores, these did not seem to translate to practically significant differences. CONCLUSION: The number of UMUX-LITE response options does not matter much, especially in practice. Because the version with three response options showed some weakness with regard to reliability and correlation with likelihood-to-recommend, practitioners should avoid it. APPLICATION: Unless there is a strong reason to do otherwise, use the "standard" version with seven response options.


Assuntos
Reprodutibilidade dos Testes , Humanos , Inquéritos e Questionários
2.
J Arthroplasty ; 29(10): 1956-60, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24927867

RESUMO

We prospectively followed 112 hips, undergoing THA with a Spectron EF stem. At mean follow-up of 11.2years, 21 patients had died. We obtained radiological follow-up in 99% and clinical follow-up in 100% of the surviving 91 hips. Fifty-four percent demonstrated osteolysis in at least one Gruen zone. Twenty-two hips required revision for all causes, with a further five stems radiologically loose. With endpoint being stem revision for aseptic loosening or radiological failure, survivorship at 11years was 0.783. We believe the addition of a rougher surface finish has contributed to the high levels of osteolysis and stem failure seen with the Spectron EF.


Assuntos
Artroplastia de Quadril/efeitos adversos , Articulação do Quadril/cirurgia , Prótese de Quadril/efeitos adversos , Artropatias/cirurgia , Falha de Prótese , Adulto , Idoso , Idoso de 80 Anos ou mais , Cimentação , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Osteólise/etiologia , Osteólise/cirurgia , Estudos Prospectivos , Desenho de Prótese , Reoperação , Fatores de Tempo , Resultado do Tratamento
3.
Ann Pharmacother ; 45(3): 297-308, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21386026

RESUMO

BACKGROUND: Risks associated with contraindicated drug-drug interaction alerts (CDDIAs) should always outweigh benefits. Misclassified CDDIAs should be eliminated. OBJECTIVE: To review CDDIAs and determine if they are contraindicated according to Food and Drug Administration-approved product labeling and if there are circumstances in which contraindicated interactions are acceptable. METHODS: A cross-sectional observational and quality improvement study was conducted over two 1-year periods. The 20 most common CDDIAs from May 2007 to May 2008 and all CDDIAs from April 2008 to April 2009 were collected at a large teaching hospital. Horizon Meds Manager used First DataBank as the knowledge base for decision support. Interactions were deemed truly contraindicated if listed in the contraindications section of the labeling of at least one of the interacting drugs. Alerts were grouped by drug and pharmacologic class to evaluate the evidence supporting the relevance of these interactions. An expert panel determined when an alert was misclassified. A medical advisory committee determined whether a contraindicated drug-drug combination was acceptable. RESULTS: Twelve (60%) of the most common 20 contraindicated interaction pairs from 2007 to 2008 were inappropriately classified. Half of the alerts were not truly contraindicated. The 8 truly contraindicated drug-drug pairs were ketorolac and other nonsteroidal antiinflammatory drugs or oral solid potassium products and anticholinergics. Half of these interactions were subsequently deemed acceptable under specific circumstances. Similar results were found in the second year, with only 55.1% of all CDDIAs being truly contraindicated despite eliminating some of the alerts that were misclassified in the first year. Nearly three fourths of legitimate CDDIAs were deemed acceptable under specific circumstances. CONCLUSIONS: Most contraindicated drug-drug interaction alerts from a commercial knowledge base were inappropriately categorized and could be downgraded. Some contraindicated drug combinations are permissible under specific circumstances. Alerts suggesting that certain drugs should never be used together, but their use together is sometimes acceptable, contribute to alert fatigue.


Assuntos
Sistemas de Notificação de Reações Adversas a Medicamentos , Interações Medicamentosas , Estudos Cross-Over , Rotulagem de Medicamentos , Quimioterapia Assistida por Computador , Hospitais/estatística & dados numéricos , Humanos , Erros de Medicação/prevenção & controle , Projetos Piloto , Melhoria de Qualidade , Sistemas de Alerta , Medição de Risco
4.
Ophthalmic Genet ; 42(1): 75-78, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-32975148

RESUMO

Background: Canavan disease is an autosomal recessive, neurodegenerative disorder caused by mutations in ASPA, a gene encoding the enzyme aspartoacylase. Patients present with macrocephaly, developmental delay, hypotonia, vision impairment and accumulation of N-acetylaspartic acid. Progressive white matter changes occur in the central nervous system. The disorder is often fatal in early childhood, but milder forms exist. Materials and methods: Case report. Results: We present the case of a 31-year-old male with mild/juvenile Canavan disease who had severe vision loss due to a retinal degeneration resembling retinitis pigmentosa. Prior to this case, vision loss in Canavan disease had been attributed to optic atrophy based on fundoscopic evidence of optic nerve pallor. Investigations for an alternative cause for our patient's retinal degeneration were non-revealing. Conclusion: We wonder if retinal degeneration may not have been previously recognized as a feature of Canavan disease. We highlight findings from animal models of Canavan disease to further support the association between Canavan disease and retinal degeneration.


Assuntos
Doença de Canavan/complicações , Degeneração Retiniana/patologia , Adulto , Humanos , Masculino , Prognóstico , Degeneração Retiniana/etiologia
5.
Can J Ophthalmol ; 41(5): 609-13, 2006 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17016535

RESUMO

CASE REPORT: We examined a unique case of stroke in a 29-year-old woman. Magnetic resonance imaging revealed isolated bilateral acute infarctions of the lateral geniculate bodies (LGB). Visual field testing demonstrated incongruous but homonymous bilateral visual field loss in a bow-tie configuration. COMMENTS: Isolated bilateral damage to the LGB is a rare event. Literature review has revealed only 4 previous incidents of bilateral damage to both LGB. We present a literature review and a case of bilateral LGB infarction producing visual field defects suggestive of bilateral lateral choroidal artery involvement in an individual with classic migraine.


Assuntos
Infarto Cerebral/complicações , Corioide/irrigação sanguínea , Corpos Geniculados/irrigação sanguínea , Transtornos da Visão/etiologia , Campos Visuais , Adulto , Colangiopancreatografia Retrógrada Endoscópica , Feminino , Humanos , Imageamento por Ressonância Magnética , Enxaqueca com Aura , Testes de Campo Visual
6.
Knee ; 19(4): 356-9, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-21636281

RESUMO

Recent reports suggest good outcome results following unicompartmental knee replacement (UKR). However, a number of authors have commented on the problem of osseous defects requiring technically difficult revision surgery. We reviewed clinical outcomes following revision total knee replacement (TKR) for failed UKR and analysed the reasons for failure and the technical aspects of the revision surgery. Between 2001 and 2010 our institute performed 132 UKR's out of which 33 required revision to TKR during a period 6 years. Demographics, details and indications for primary and revision surgery, the revised prosthesis including augments, technical difficulties and complications were noted. Patient outcome assessment was based on the Oxford knee score (OKS). Survival analysis for the UKR prosthesis was calculated using Kaplan-Meier Survival curves. Reasons for revision included aseptic loosening, persistent pain, dislocated meniscus, mal-alignment and other compartment osteoarthritis. Median time to revision was 19 months (range 2-159). Using revision as the end-point the survival proportion at 5-years was 69%. 18 revisions required additional intra-operative constructs including stemmed implants, wedge augmentation or bone graft. The mean 1 year post-operative OKS was 29 compared to 39 for primary TKR during the same period (p<0.001). Aseptic loosening was the commonest mode of failure. UKR survivorship at a non-specialist institute is considerably lower than at originating centres. Two thirds of the revisions were technically difficult and required additional constructs. The clinical outcome after revision surgery was inferior to that of primary TKR. The role of UKR needs to be more clearly defined.


Assuntos
Artroplastia do Joelho/métodos , Adulto , Idoso , Feminino , Humanos , Prótese do Joelho , Masculino , Pessoa de Meia-Idade , Falha de Prótese , Reoperação , Falha de Tratamento
8.
Behav Res Methods ; 41(3): 951-6, 2009 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19587212

RESUMO

An emerging area of research in engineering psychology is the evaluation of text entry for mobile devices using a small number of keys for the control of cursor direction and character selection from a matrix of characters (i.e., selection-based data entry). The present article describes a software tool designed to reduce time and effort in the development of prototypes of alternative selection-based text-entry schemes and their empirical evaluation. The tool, available for distribution to researchers, educators, and students, uses Action Script code compiled into an executable file that has an embedded Adobe Flash Player and is compatible with most operating systems (including Microsoft Windows, Apple OSX, and Linux).


Assuntos
Pesquisa Comportamental/instrumentação , Pesquisa Comportamental/métodos , Coleta de Dados/instrumentação , Coleta de Dados/métodos , Periféricos de Computador , Interface Usuário-Computador
9.
Hum Factors ; 50(1): 77-89, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-18354973

RESUMO

OBJECTIVE: The primary purpose of this experiment was to gain a greater understanding of the utilization of working memory when interacting with a speech-enabled interactive voice response (IVR) system. BACKGROUND: A widely promoted guideline advises limiting IVR menus to five or fewer items because of constraints of the human memory system, commonly citing Miller's (1956) paper. The authors argue that Miller's paper does not, in fact, support this guideline. Furthermore, applying modern theories of working memory leads to the opposite conclusion--that reducing menu length by creating a deeper structure is actually more demanding of users' working memories and leads to poorer performance and satisfaction. METHOD: Participants took a working memory capacity test and then attempted to complete a series of e-mail tasks using one of two IVR designs (functionally equivalent, but one with a broad menu structure and the other with a deep structure). RESULTS: Users of the broad-structure IVR performed better and were more satisfied than users of the deep-structure IVR. Furthermore, this effect was more pronounced for those with low working memory capacity. CONCLUSION: Results indicate that creating a deeper structure is more demanding of working memory resource than the alternative of longer, shallower menus. APPLICATION: This experiment has important practical implications for all systems with auditory menus (particularly IVRs) because it provides empirical evidence refuting a widely promoted design practice.


Assuntos
Design de Software , Interface para o Reconhecimento da Fala , Interface Usuário-Computador , Adolescente , Adulto , Correio Eletrônico , Florida , Humanos , Análise e Desempenho de Tarefas
10.
Eur J Trauma Emerg Surg ; 33(3): 256-61, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26814489

RESUMO

BACKGROUND AND PURPOSE: In this institution, the management of displaced (Gartland III) supracondylar fractures in children was changed from overhead olecranon screw traction to manipulation and percutaneous wiring in 1996. The purpose of this study was to compare the two methods of treatment and observe whether the decision to change management was justified. METHODS: A retrospective study of two cohorts; 151 patients between 1986 and 1996 treated with olecranon screw traction and 92 patients between 1996 and 2002 treated with percutaneous wiring. Both sets of patients were followed up clinically and radiologically until the child could demonstrate a satisfactory range of movement and the fracture had united. RESULTS: There were no differences in the clinical outcomes between the two groups. The main difference between the groups was in length of stay, which was a median of 1 day in the wired group and 14 days in the traction group. CONCLUSION: Outcomes achieved from percutaneous wiring of displaced supracondylar fractures are similar to those from olecranon screw traction. The advantage of percutaneous wiring to both patient and provider is the reduced hospital stay. The decision to change management therefore appears to be justified. However, percutaneous wiring is generally a technically more demanding procedure and olecranon screw traction should remain a possible treatment option for the management of this injury.

11.
Dalton Trans ; (19): 3221-8, 2005 Oct 07.
Artigo em Inglês | MEDLINE | ID: mdl-16172648

RESUMO

The molecular structures of Se(SCH(3))(2) and Te(SCH(3))(2) were investigated using gas-phase electron diffraction (GED) and ab initio and DFT geometry optimisations. While parameters involving H atoms were refined using flexible restraints according to the SARACEN method, parameters that depended only on heavy atoms could be refined without restraints. The GED-determined geometric parameters (r(h1)) are: rSe-S 219.1(1), rS-C 183.2(1), rC-H 109.6(4) pm; angleS-Se-S 102.9(3), angleSe-S-C 100.6(2), angleS-C-H (mean) 107.4(5), phiS-Se-S-C 87.9(20), phiSe-S-C-H 178.8(19) degrees for Se(SCH(3))(2), and rTe-S 238.1(2), rS-C 184.1(3), rC-H 110.0(6) pm; angleS-Te-S 98.9(6), angleTe-S-C 99.7(4), angleS-C-H (mean) 109.2(9), phiS-Te-S-C 73.0(48), phiTe-S-C-H 180.1(19) degrees for Te(SCH(3))(2). Ab initio and DFT calculations were performed at the HF, MP2 and B3LYP levels, employing either full-electron basis sets [3-21G(d) or 6-31G(d)] or an effective core potential with a valence basis set [LanL2DZ(d)]. The best fit to the GED structures was achieved at the MP2 level. Differences between GED and MP2 results for rS-C and angleS-Te-S were explained by the thermal population of excited vibrational states under the experimental conditions. All theoretical models agreed that each compound exists as two stable conformers, one in which the methyl groups are on the same side (g(+)g(-) conformer) and one in which they are on different sides (g(+)g(+) conformer) of the S-Y-S plane (Y = Se, Te). The conformational composition under the experimental conditions could not be resolved from the GED data. Despite GED R-factors and ab initio and DFT energies favouring the g(+)g(+) conformer, it is likely that both conformers are present, for Se(SCH(3))(2) as well as for Te(SCH(3))(2).


Assuntos
Compostos de Selênio/química , Sulfetos/química , Telúrio/química , Elétrons , Estrutura Molecular
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