Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas.

Kummar, Shivaani; Shen, Lin; Hong, David S; McDermott, Ray; Keedy, Vicki L; Casanova, Michela; Demetri, George D; Dowlati, Afshin; Melcón, Soledad Gallego; Lassen, Ulrik N; Leyvraz, Serge; Liu, Tianshu; Moreno, Victor; Patel, Jyoti; Patil, Tejas; Mallick, Atrayee Basu; Sousa, Nuno; Tahara, Makoto; Ziegler, David S; Norenberg, Ricarda; Arvis, Pierre; Brega, Nicoletta; Drilon, Alexander; Tan, Daniel S W.

Cancer ; 129(23): 3772-3782, 2023 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-37769113

2.

Genomic and transcriptomic landscape of conjunctival melanoma.

Cisarova, Katarina; Folcher, Marc; El Zaoui, Ikram; Pescini-Gobert, Rosanna; Peter, Virginie G; Royer-Bertrand, Beryl; Zografos, Leonidas; Schalenbourg, Ann; Nicolas, Michael; Rimoldi, Donata; Leyvraz, Serge; Riggi, Nicolò; Moulin, Alexandre P; Rivolta, Carlo.

PLoS Genet ; 16(12): e1009201, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33383577

3.

Rationale and design of ON-TRK: a novel prospective non-interventional study in patients with TRK fusion cancer treated with larotrectinib.

Yang, James C H; Brose, Marcia S; Castro, Gilberto; Kim, Edward S; Lassen, Ulrik N; Leyvraz, Serge; Pappo, Alberto; López-Ríos, Fernando; Reeves, John A; Fellous, Marc; Penault-Llorca, Frédérique; Rudzinski, Erin R; Tabatabai, Ghazaleh; Vassal, Gilles; Drilon, Alexander; Trent, Jonathan.

BMC Cancer ; 22(1): 625, 2022 Jun 07.

Artigo em Inglês | MEDLINE | ID: mdl-35672677

4.

Uveal Melanoma - Standardised Procedure in Diagnosis, Therapy and Surveillance. / Das uveale Melanom standardisiertes Vorgehen in Diagnostik, Therapie und Nachsorge.

Bechrakis, Nikolaos E; Bornfeld, Norbert; Heindl, Ludwig M; Skoetz, Nicole; Leyvraz, Serge; Joussen, Antonia M.

Klin Monbl Augenheilkd ; 238(7): 761-772, 2021 Jul.

Artigo em Inglês, Alemão | MEDLINE | ID: mdl-34376006

5.

Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing.

Royer-Bertrand, Beryl; Torsello, Matteo; Rimoldi, Donata; El Zaoui, Ikram; Cisarova, Katarina; Pescini-Gobert, Rosanna; Raynaud, Franck; Zografos, Leonidas; Schalenbourg, Ann; Speiser, Daniel; Nicolas, Michael; Vallat, Laureen; Klein, Robert; Leyvraz, Serge; Ciriello, Giovanni; Riggi, Nicolò; Moulin, Alexandre P; Rivolta, Carlo.

Am J Hum Genet ; 99(5): 1190-1198, 2016 Nov 03.

Artigo em Inglês | MEDLINE | ID: mdl-27745836

6.

Long-term outcome of dasatinib first-line treatment in gastrointestinal stromal tumor: A multicenter, 2-stage phase 2 trial (Swiss Group for Clinical Cancer Research 56/07).

Montemurro, Michael; Cioffi, Angela; Dômont, Julien; Rutkowski, Piotr; Roth, Arnaud D; von Moos, Roger; Inauen, Roman; Toulmonde, Maud; Burkhard, Roger O; Knuesli, Claudio; Bauer, Sebastian; Cassier, Philippe; Schwarb, Heike; Le Cesne, Axel; Koeberle, Dieter; Bärtschi, Daniela; Dietrich, Daniel; Biaggi, Christine; Prior, John; Leyvraz, Serge.

Cancer ; 124(7): 1449-1454, 2018 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-29315500

7.

Lenalidomide maintenance after stem-cell transplantation for multiple myeloma.

Attal, Michel; Lauwers-Cances, Valerie; Marit, Gerald; Caillot, Denis; Moreau, Philippe; Facon, Thierry; Stoppa, Anne Marie; Hulin, Cyrille; Benboubker, Lofti; Garderet, Laurent; Decaux, Olivier; Leyvraz, Serge; Vekemans, Marie-Christiane; Voillat, Laurent; Michallet, Mauricette; Pegourie, Brigitte; Dumontet, Charles; Roussel, Murielle; Leleu, Xavier; Mathiot, Claire; Payen, Catherine; Avet-Loiseau, Hervé; Harousseau, Jean-Luc.

N Engl J Med ; 366(19): 1782-91, 2012 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-22571202

8.

Health-related quality-of-life in patients with newly diagnosed multiple myeloma in the FIRST trial: lenalidomide plus low-dose dexamethasone versus melphalan, prednisone, thalidomide.

Delforge, Michel; Minuk, Leonard; Eisenmann, Jean-Claude; Arnulf, Bertrand; Canepa, Letizia; Fragasso, Alberto; Leyvraz, Serge; Langer, Christian; Ezaydi, Yousef; Vogl, Dan T; Giraldo-Castellano, Pilar; Yoon, Sung-Soo; Zarnitsky, Charles; Escoffre-Barbe, Martine; Lemieux, Bernard; Song, Kevin; Bahlis, Nizar Jacques; Guo, Shien; Monzini, Mara Silva; Ervin-Haynes, Annette; Houck, Vanessa; Facon, Thierry.

Haematologica ; 100(6): 826-33, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25769541

9.

MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial.

Romano, Emanuela; Michielin, Olivier; Voelter, Verena; Laurent, Julien; Bichat, Hélène; Stravodimou, Athina; Romero, Pedro; Speiser, Daniel E; Triebel, Frédéric; Leyvraz, Serge; Harari, Alexandre.

J Transl Med ; 12: 97, 2014 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-24726012

10.

A three-arm randomised phase II study of the MEK inhibitor selumetinib alone or in combination with paclitaxel in metastatic uveal melanoma.

Sacco, Joseph J; Jackson, Richard; Corrie, Pippa; Danson, Sarah; Evans, T R Jeffry; Ochsenreither, Sebastian; Kumar, Satish; Goodman, Andrew; Larkin, James; Karydis, Ioannis; Steven, Neil; Lorigan, Paul; Plummer, Ruth; Patel, Poulam; Psarelli, Eftychia; Olsson-Brown, Anna; Shaw, Heather; Leyvraz, Serge; Handley, Louise; Rawcliffe, Charlotte; Nathan, Paul.

Eur J Cancer ; 202: 114009, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38547774

11.

Prediction of free imatinib concentrations based on total plasma concentrations in patients with gastrointestinal stromal tumours.

Haouala, Amina; Widmer, Nicolas; Guidi, Monia; Montemurro, Michael; Leyvraz, Serge; Buclin, Thierry; Eap, Chin B; Decosterd, Laurent A; Csajka, Chantal.

Br J Clin Pharmacol ; 75(4): 1007-18, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-22891806

12.

Tumour mutational burden and survival with molecularly matched therapy.

de Bortoli, Till; Benary, Manuela; Horak, Peter; Lamping, Mario; Stintzing, Sebastian; Tinhofer, Ingeborg; Leyvraz, Serge; Schäfer, Reinhold; Klauschen, Frederick; Keller, Ulrich; Stenzinger, Albrecht; Fröhling, Stefan; Kurzrock, Razelle; Keilholz, Ulrich; Rieke, Damian T; Jelas, Ivan.

Eur J Cancer ; 190: 112925, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37544709

13.

A Phase I Study of the Pan-Notch Inhibitor CB-103 for Patients with Advanced Adenoid Cystic Carcinoma and Other Tumors.

Hanna, Glenn J; Stathis, Anastasios; Lopez-Miranda, Elena; Racca, Fabricio; Quon, Doris; Leyvraz, Serge; Hess, Dagmar; Keam, Bhumsuk; Rodon, Jordi; Ahn, Myung-Ju; Kim, Hye Ryun; Schneeweiss, Andreas; Ribera, Josep-Maria; DeAngelo, Daniel; Perez Garcia, Jose Manuel; Cortes, Javier; Schönborn-Kellenberger, Oliver; Weber, Dirk; Pisa, Pavel; Bauer, Michael; Beni, Laura; Bobadilla, Maria; Lehal, Raj; Vigolo, Michele; Vogl, Florian D; Garralda, Elena.

Cancer Res Commun ; 3(9): 1853-1861, 2023 09 14.

Artigo em Inglês | MEDLINE | ID: mdl-37712875

14.

Ocular melanoma: what's new?

Leyvraz, Serge; Keilholz, Ulrich.

Curr Opin Oncol ; 24(2): 162-9, 2012 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-22234256

15.

Home care--a safe and attractive alternative to inpatient administration of intensive chemotherapies.

Lüthi, François; Fucina, Nadia; Divorne, Nathalie; Santos-Eggimann, Brigitte; Currat-Zweifel, Christine; Rollier, Patricia; Wasserfallen, Jean-Blaise; Ketterer, Nicolas; Leyvraz, Serge.

Support Care Cancer ; 20(3): 575-81, 2012 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-21384139

16.

Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase Fusion-Positive Lung Cancers.

Drilon, Alexander; Tan, Daniel S W; Lassen, Ulrik N; Leyvraz, Serge; Liu, Yongmei; Patel, Jyoti D; Rosen, Lee; Solomon, Benjamin; Norenberg, Ricarda; Dima, Laura; Brega, Nicoletta; Shen, Lin; Moreno, Victor; Kummar, Shivaani; Lin, Jessica J.

JCO Precis Oncol ; 6: e2100418, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-35085007

17.

Efficacy and safety of larotrectinib in patients with TRK fusion-positive thyroid carcinoma.

Waguespack, Steven G; Drilon, Alexander; Lin, Jessica J; Brose, Marcia S; McDermott, Ray; Almubarak, Mohammed; Bauman, Jessica; Casanova, Michela; Krishnamurthy, Anuradha; Kummar, Shivaani; Leyvraz, Serge; Oh, Do-Youn; Park, Keunchil; Sohal, Davendra; Sherman, Eric; Norenberg, Ricarda; Silvertown, Josh D; Brega, Nicoletta; Hong, David S; Cabanillas, Maria E.

Eur J Endocrinol ; 186(6): 631-643, 2022 Apr 29.

Artigo em Inglês | MEDLINE | ID: mdl-35333737

18.

Biomarker-driven therapies for metastatic uveal melanoma: A prospective precision oncology feasibility study.

Leyvraz, Serge; Konietschke, Frank; Peuker, Caroline; Schütte, Moritz; Kessler, Thomas; Ochsenreither, Sebastian; Ditzhaus, Marc; Sprünken, Erin D; Dörpholz, Gina; Lamping, Mario; Rieke, Damian T; Klinghammer, Konrad; Burock, Susen; Ulrich, Claas; Poch, Gabriela; Schäfer, Reinhold; Klauschen, Frederick; Joussen, Antonia; Yaspo, Marie-Laure; Keilholz, Ulrich.

Eur J Cancer ; 169: 146-155, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35569281

19.

Clinical and molecular response to tebentafusp in previously treated patients with metastatic uveal melanoma: a phase 2 trial.

Carvajal, Richard D; Butler, Marcus O; Shoushtari, Alexander N; Hassel, Jessica C; Ikeguchi, Alexandra; Hernandez-Aya, Leonel; Nathan, Paul; Hamid, Omid; Piulats, Josep M; Rioth, Matthew; Johnson, Douglas B; Luke, Jason J; Espinosa, Enrique; Leyvraz, Serge; Collins, Laura; Goodall, Howard M; Ranade, Koustubh; Holland, Chris; Abdullah, Shaad E; Sacco, Joseph J; Sato, Takami.

Nat Med ; 28(11): 2364-2373, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36229663

20.

UV light signature in conjunctival melanoma; not only skin should be protected from solar radiation.

Rivolta, Carlo; Royer-Bertrand, Beryl; Rimoldi, Donata; Schalenbourg, Ann; Zografos, Leonidas; Leyvraz, Serge; Moulin, Alexandre.

J Hum Genet ; 61(4): 361-2, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26657935

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