Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Dual-role transcription factors stabilize intermediate expression levels.

He, Jinnan; Huo, Xiangru; Pei, Gaofeng; Jia, Zeran; Yan, Yiming; Yu, Jiawei; Qu, Haozhi; Xie, Yunxin; Yuan, Junsong; Zheng, Yuan; Hu, Yanyan; Shi, Minglei; You, Kaiqiang; Li, Tingting; Ma, Tianhua; Zhang, Michael Q; Ding, Sheng; Li, Pilong; Li, Yinqing.

Cell ; 2024 Apr 10.

Artigo em Inglês | MEDLINE | ID: mdl-38631355

2.

CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.

Ma, Xinyu; Lu, Caijing; Chen, Yuting; Li, Shulin; Ma, Ningjia; Tao, Xuan; Li, Ying; Wang, Jing; Zhou, Min; Yan, Yong-Bin; Li, Pilong; Heydari, Kartoosh; Deng, Haiteng; Zhang, Min; Yi, Cong; Ge, Liang.

Cell ; 185(8): 1325-1345.e22, 2022 04 14.

Artigo em Inglês | MEDLINE | ID: mdl-35366418

3.

SAFB restricts contact domain boundaries associated with L1 chimeric transcription.

Hong, Yaqiang; Bie, Luyao; Zhang, Tao; Yan, Xiaohan; Jin, Guangpu; Chen, Zhuo; Wang, Yang; Li, Xiufeng; Pei, Gaofeng; Zhang, Yongyan; Hong, Yantao; Gong, Liang; Li, Pilong; Xie, Wei; Zhu, Yanfen; Shen, Xiaohua; Liu, Nian.

Mol Cell ; 84(9): 1637-1650.e10, 2024 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-38604171

4.

Transitions in the framework of condensate biology.

Seydoux, Geraldine; Zhang, Mingjie; Forman-Kay, Julie D; McStay, Brian; Liu, Kathy Fange; Li, Pilong.

Mol Cell ; 83(7): 1016-1021, 2023 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-37028411

5.

Substrate-induced condensation activates plant TIR domain proteins.

Song, Wen; Liu, Li; Yu, Dongli; Bernardy, Hanna; Jirschitzka, Jan; Huang, Shijia; Jia, Aolin; Jemielniak, Wictoria; Acker, Julia; Laessle, Henriette; Wang, Junli; Shen, Qiaochu; Chen, Weijie; Li, Pilong; Parker, Jane E; Han, Zhifu; Schulze-Lefert, Paul; Chai, Jijie.

Nature ; 627(8005): 847-853, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38480885

6.

Struggle for survival: new insights into NELF condensation for adaptive transcriptional reprogramming.

Xu, Weifan; Ding, Mingrui; Li, Pilong.

Mol Cell ; 81(5): 896-898, 2021 03 04.

Artigo em Inglês | MEDLINE | ID: mdl-33667379

7.

Histone H2B.8 compacts flowering plant sperm through chromatin phase separation.

Buttress, Toby; He, Shengbo; Wang, Liang; Zhou, Shaoli; Saalbach, Gerhard; Vickers, Martin; Li, Guohong; Li, Pilong; Feng, Xiaoqi.

Nature ; 611(7936): 614-622, 2022 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-36323776

8.

Linker histone H1 drives heterochromatin condensation via phase separation in Arabidopsis.

He, Shengbo; Yu, Yiming; Wang, Liang; Zhang, Jingyi; Bai, Zhengyong; Li, Guohong; Li, Pilong; Feng, Xiaoqi.

Plant Cell ; 36(5): 1829-1843, 2024 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-38309957

9.

Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism.

Wang, Liang; Gao, Yifei; Zheng, Xiangdong; Liu, Cuifang; Dong, Shuangshuang; Li, Ru; Zhang, Guanwei; Wei, Yixuan; Qu, Hongyuan; Li, Yuhan; Allis, C David; Li, Guohong; Li, Haitao; Li, Pilong.

Mol Cell ; 76(4): 646-659.e6, 2019 11 21.

Artigo em Inglês | MEDLINE | ID: mdl-31543422

10.

RNA Targets Ribogenesis Factor WDR43 to Chromatin for Transcription and Pluripotency Control.

Bi, Xianju; Xu, Yanhui; Li, Tong; Li, Xinmin; Li, Wenzhi; Shao, Wen; Wang, Kaili; Zhan, Ge; Wu, Zhongyang; Liu, Wei; Lu, J Yuyang; Wang, Liang; Zhao, Jicheng; Wu, Jiawei; Na, Jie; Li, Guohong; Li, Pilong; Shen, Xiaohua.

Mol Cell ; 75(1): 102-116.e9, 2019 07 11.

Artigo em Inglês | MEDLINE | ID: mdl-31128943

11.

Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly.

Zhang, Rundong; So, Byung Ran; Li, Pilong; Yong, Jeongsik; Glisovic, Tina; Wan, Lili; Dreyfuss, Gideon.

Cell ; 146(3): 384-95, 2011 Aug 05.

Artigo em Inglês | MEDLINE | ID: mdl-21816274

12.

Dissolution of oncofusion transcription factor condensates for cancer therapy.

Wang, Yuan; Yu, Chunyu; Pei, Gaofeng; Jia, Wen; Li, Tingting; Li, Pilong.

Nat Chem Biol ; 19(10): 1223-1234, 2023 10.

Artigo em Inglês | MEDLINE | ID: mdl-37400539

13.

Gelation of cytoplasmic expanded CAG RNA repeats suppresses global protein synthesis.

Pan, Yuyin; Lu, Junmei; Feng, Xinran; Lu, Shengyi; Yang, Yi; Yang, Guang; Tan, Shudan; Wang, Liang; Li, Pilong; Luo, Shouqing; Lu, Boxun.

Nat Chem Biol ; 19(11): 1372-1383, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37592155

14.

Structural and energetic mechanisms of cooperative autoinhibition and activation of Vav1.

Yu, Bingke; Martins, Ilídio R S; Li, Pilong; Amarasinghe, Gaya K; Umetani, Junko; Fernandez-Zapico, Martin E; Billadeau, Daniel D; Machius, Mischa; Tomchick, Diana R; Rosen, Michael K.

Cell ; 140(2): 246-56, 2010 Jan 22.

Artigo em Inglês | MEDLINE | ID: mdl-20141838

15.

Arabidopsis FLL2 promotes liquid-liquid phase separation of polyadenylation complexes.

Fang, Xiaofeng; Wang, Liang; Ishikawa, Ryo; Li, Yaoxi; Fiedler, Marc; Liu, Fuquan; Calder, Grant; Rowan, Beth; Weigel, Detlef; Li, Pilong; Dean, Caroline.

Nature ; 569(7755): 265-269, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-31043738

16.

Screening membraneless organelle participants with machine-learning models that integrate multimodal features.

Chen, Zhaoming; Hou, Chao; Wang, Liang; Yu, Chunyu; Chen, Taoyu; Shen, Boyan; Hou, Yaoyao; Li, Pilong; Li, Tingting.

Proc Natl Acad Sci U S A ; 119(24): e2115369119, 2022 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-35687670

17.

Acquired 'Phase Separation' Underlies Aberrant Cell Fate Control?

Gao, Yifei; Li, Pilong.

Trends Biochem Sci ; 45(6): 457-458, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32413321

18.

A brief guideline for studies of phase-separated biomolecular condensates.

Gao, Yifei; Li, Xi; Li, Pilong; Lin, Yi.

Nat Chem Biol ; 18(12): 1307-1318, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-36400991

19.

Programming cell-surface signaling by phase-separation-controlled compartmentalization.

Li, Ru; Li, Tiantian; Lu, Genzhe; Cao, Zhi; Chen, Bowen; Wang, Yalong; Du, Juanjuan; Li, Pilong.

Nat Chem Biol ; 18(12): 1351-1360, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-36396954

20.

PHF1 compartmentalizes PRC2 via phase separation.

Lu, Genzhe; Li, Pilong.

Biochem J ; 480(22): 1833-1844, 2023 11 29.

Artigo em Inglês | MEDLINE | ID: mdl-37888776

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