Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Nitrile biosynthesis in nature: how and why?

Liu, Mingyu; Li, Shengying.

Nat Prod Rep ; 41(4): 649-671, 2024 Apr 24.

Artigo em Inglês | MEDLINE | ID: mdl-38193577

2.

Identification and characterization of a novel hydroxylamine oxidase, DnfA, that catalyzes the oxidation of hydroxylamine to N₂.

Wu, Meng-Ru; Miao, Li-Li; Liu, Ying; Qian, Xin-Xin; Hou, Ting-Ting; Ai, Guo-Min; Yu, Lu; Ma, Lan; Gao, Xi-Yan; Qin, Ya-Ling; Zhu, Hai-Zhen; Du, Lei; Li, Sheng-Ying; Tian, Chang-Lin; Li, De-Feng; Liu, Zhi-Pei; Liu, Shuang-Jiang.

J Biol Chem ; 298(9): 102372, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35970391

3.

Biosynthesis of 4-Acyl-5-aminoimidazole Alkaloids Featuring a New Friedel-Crafts Acyltransferase.

Xia, Yuwei; Zhu, Guoliang; Zhang, Xingwang; Li, Shengying; Du, Lei; Zhu, Weiming.

J Am Chem Soc ; 145(48): 26308-26317, 2023 12 06.

Artigo em Inglês | MEDLINE | ID: mdl-37983668

4.

Effect of chromosomal integration on catalytic performance of a multi-component P450 system in Escherichia coli.

Luelf, U Joost; Böhmer, Lisa M; Li, Shengying; Urlacher, Vlada B.

Biotechnol Bioeng ; 120(7): 1762-1772, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37186287

5.

Crystal structures of Î³-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine.

Wang, Ning; Chen, Xiu-Lan; Gao, Chao; Peng, Ming; Wang, Peng; Zhang, Na; Li, Fuchuan; Yang, Gui-Peng; Shen, Qing-Tao; Li, Shengying; Chen, Yin; Zhang, Yu-Zhong; Li, Chun-Yang.

J Biol Chem ; 296: 100081, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33199371

6.

RNA-Seq analysis reveals the important co-expressed genes associated with polyphyllin biosynthesis during the developmental stages of Paris polyphylla.

Gao, Xiaoyang; Su, Qixuan; Li, Jing; Yang, Wenjing; Yao, Baolin; Guo, Jiawei; Li, Shengying; Liu, Changning.

BMC Genomics ; 23(Suppl 1): 559, 2022 Aug 05.

Artigo em Inglês | MEDLINE | ID: mdl-35931959

7.

Diversification of phenolic glucosides by two UDP-glucosyltransferases featuring complementary regioselectivity.

Guo, Fei; Zhang, Xingwang; You, Cai; Zhang, Chengjie; Li, Fengwei; Li, Nan; Xia, Yuwei; Liu, Mingyu; Qiu, Zetian; Zheng, Xianliang; Ma, Li; Zhang, Gang; Luo, Lianzhong; Cao, Fei; Feng, Yingang; Zhao, Guang-Rong; Zhang, Wei; Li, Shengying; Du, Lei.

Microb Cell Fact ; 21(1): 208, 2022 Oct 10.

Artigo em Inglês | MEDLINE | ID: mdl-36217200

8.

Compartmentalized biosynthesis of mycophenolic acid.

Zhang, Wei; Du, Lei; Qu, Zepeng; Zhang, Xingwang; Li, Fengwei; Li, Zhong; Qi, Feifei; Wang, Xiao; Jiang, Yuanyuan; Men, Ping; Sun, Jingran; Cao, Shaona; Geng, Ce; Qi, Fengxia; Wan, Xiaobo; Liu, Changning; Li, Shengying.

Proc Natl Acad Sci U S A ; 116(27): 13305-13310, 2019 07 02.

Artigo em Inglês | MEDLINE | ID: mdl-31209052

9.

Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications.

Li, Zhong; Jiang, Yuanyuan; Guengerich, F Peter; Ma, Li; Li, Shengying; Zhang, Wei.

J Biol Chem ; 295(3): 833-849, 2020 01 17.

Artigo em Inglês | MEDLINE | ID: mdl-31811088

10.

Cytochrome P450 enzymes in fungal natural product biosynthesis.

Zhang, Xingwang; Guo, Jiawei; Cheng, Fangyuan; Li, Shengying.

Nat Prod Rep ; 38(6): 1072-1099, 2021 06 23.

Artigo em Inglês | MEDLINE | ID: mdl-33710221

11.

Challenges and potential for improving the druggability of podophyllotoxin-derived drugs in cancer chemotherapy.

Zhao, Wei; Cong, Ying; Li, Hong-Mei; Li, Shengying; Shen, Yuemao; Qi, Qingsheng; Zhang, Youming; Li, Yue-Zhong; Tang, Ya-Jie.

Nat Prod Rep ; 38(3): 470-488, 2021 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-32895676

12.

Structural Basis for Selective Oxidation of Phosphorylated Ethylphenols by Cytochrome P450 Monooxygenase CreJ.

Dong, Sheng; Chen, Jingfei; Zhang, Xingwang; Guo, Fei; Ma, Li; You, Cai; Wang, Xiao; Zhang, Wei; Wan, Xiaobo; Liu, Shuang-Jiang; Yao, Li-Shan; Li, Shengying; Du, Lei; Feng, Yingang.

Appl Environ Microbiol ; 87(11)2021 05 11.

Artigo em Inglês | MEDLINE | ID: mdl-33712426

13.

Bacterial Biosynthetic P450 Enzyme PikC_D50N: A Potential Biocatalyst for the Preparation of Human Drug Metabolites.

Guo, Jiawei; Li, Fengwei; Cheng, Fangyuan; Ma, Li; Liu, Xiaohui; Durairaj, Pradeepraj; Zhang, Gang; Tang, Dandan; Long, Xiangtian; Zhang, Wei; Du, Lei; Zhang, Xingwang; Li, Shengying.

J Org Chem ; 86(21): 14563-14571, 2021 11 05.

Artigo em Inglês | MEDLINE | ID: mdl-34662127

14.

Microbulbifer hainanensis sp. nov., a moderately halopilic bacterium isolated from mangrove sediment.

Cheng, Yuping; Zhu, Suting; Guo, Chaobo; Xie, Feilu; Jung, Dawoon; Li, Shengying; Zhang, Weiyan; He, Shan.

Antonie Van Leeuwenhoek ; 114(7): 1033-1042, 2021 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-33844121

15.

Engineering Bafilomycin High-Producers by Manipulating Regulatory and Biosynthetic Genes in the Marine Bacterium Streptomyces lohii.

Li, Zhong; Li, Shuai; Du, Lei; Zhang, Xingwang; Jiang, Yuanyuan; Liu, Wenhua; Zhang, Wei; Li, Shengying.

Mar Drugs ; 19(1)2021 Jan 11.

Artigo em Inglês | MEDLINE | ID: mdl-33440628

16.

Unexpected Reactions of α,ß-Unsaturated Fatty Acids Provide Insight into the Mechanisms of CYP152 Peroxygenases.

Jiang, Yuanyuan; Peng, Wei; Li, Zhong; You, Cai; Zhao, Yue; Tang, Dandan; Wang, Binju; Li, Shengying.

Angew Chem Int Ed Engl ; 60(46): 24694-24701, 2021 11 08.

Artigo em Inglês | MEDLINE | ID: mdl-34523786

17.

Biosynthesis of Chuangxinmycin Featuring a Deubiquitinase-like Sulfurtransferase.

Zhang, Xingwang; Xu, Xiaokun; You, Cai; Yang, Chaofan; Guo, Jiawei; Sang, Moli; Geng, Ce; Cheng, Fangyuan; Du, Lei; Shen, Yuemao; Wang, Sheng; Lan, Haidong; Yang, Fan; Li, Yuezhong; Tang, Ya-Jie; Zhang, Youming; Bian, Xiaoying; Li, Shengying; Zhang, Wei.

Angew Chem Int Ed Engl ; 60(46): 24418-24423, 2021 11 08.

Artigo em Inglês | MEDLINE | ID: mdl-34498345

18.

Flavin-Dependent Monooxygenases NotI and NotI' Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides.

Fraley, Amy E; Tran, Hong T; Kelly, Samantha P; Newmister, Sean A; Tripathi, Ashootosh; Kato, Hikaru; Tsukamoto, Sachiko; Du, Lei; Li, Shengying; Williams, Robert M; Sherman, David H.

Chembiochem ; 21(17): 2449-2454, 2020 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-32246875

19.

Rheinheimera mangrovi sp. nov., a bacterium isolated from mangrove sediment.

Zhang, Weiyan; Zhu, Suting; Cheng, Yuping; Ding, Lijian; Li, Shengying; Peng, Nan; He, Shan.

Int J Syst Evol Microbiol ; 70(12): 6188-6194, 2020 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-33052808

20.

Efficient targeted mutation of genomic essential genes in yeast Saccharomyces cerevisiae.

Yang, Shan; Cao, Xuan; Yu, Wei; Li, Shengying; Zhou, Yongjin J.

Appl Microbiol Biotechnol ; 104(7): 3037-3047, 2020 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-32043190

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