Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.

Liu, Chia-Chen; Wang, Na; Chen, Yuanxin; Inoue, Yasuteru; Shue, Francis; Ren, Yingxue; Wang, Minghui; Qiao, Wenhui; Ikezu, Tadafumi C; Li, Zonghua; Zhao, Jing; Martens, Yuka; Doss, Sydney V; Rosenberg, Cassandra L; Jeevaratnam, Suren; Jia, Lin; Raulin, Ana-Caroline; Qi, Fangfang; Zhu, Yiyang; Alnobani, Alla; Knight, Joshua; Chen, Yixing; Linares, Cynthia; Kurti, Aishe; Fryer, John D; Zhang, Bin; Wu, Long-Jun; Kim, Betty Y S; Bu, Guojun.

Nat Immunol ; 24(11): 1854-1866, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37857825

2.

ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism.

Kawatani, Keiji; Holm, Marie-Louise; Starling, Skylar C; Martens, Yuka A; Zhao, Jing; Lu, Wenyan; Ren, Yingxue; Li, Zonghua; Jiang, Peizhou; Jiang, Yangying; Baker, Samantha K; Wang, Ni; Roy, Bhaskar; Parsons, Tammee M; Perkerson, Ralph B; Bao, Hanmei; Han, Xianlin; Bu, Guojun; Kanekiyo, Takahisa.

Mol Psychiatry ; 29(3): 809-819, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38135757

3.

APOE2 Exacerbates TDP-43 Related Toxicity in the Absence of Alzheimer Pathology.

Meneses, Axel D; Koga, Shunsuke; Li, Zonghua; O'Leary, Justin; Li, Fuyao; Chen, Kai; Murakami, Aya; Qiao, Wenhui; Kurti, Aishe; Heckman, Michael G; White, Launia; Xie, Manling; Chen, Yixing; Finch, Nicole A; Lim, Melina J; Delenclos, Marion; DeTure, Michael A; Linares, Cynthia; Martin, Nicholas B; Ikezu, Tadafumi C; van Blitterswijk, Marka M; Wu, Long-Jun; McLean, Pamela J; Rademakers, Rosa; Ross, Owen A; Dickson, Dennis W; Bu, Guojun; Zhao, Na.

Ann Neurol ; 93(4): 830-843, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36546684

4.

APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.

Jin, Yunjung; Li, Fuyao; Sonoustoun, Berkiye; Kondru, Naveen Chandra; Martens, Yuka A; Qiao, Wenhui; Heckman, Michael G; Ikezu, Tadafumi C; Li, Zonghua; Burgess, Jeremy D; Amerna, Danilyn; O'Leary, Justin; DeTure, Michael A; Zhao, Jing; McLean, Pamela J; Dickson, Dennis W; Ross, Owen A; Bu, Guojun; Zhao, Na.

Acta Neuropathol ; 143(6): 641-662, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35471463

5.

Combination of smoking and Epstein-Barr virus DNA is a predictor of poor prognosis for nasopharyngeal carcinoma: a long-term follow-up retrospective study.

Li, Wanxia; Yang, Chao; Zhao, Feipeng; Li, Junzheng; Li, Zonghua; Ouyang, Ping; Yuan, Xiaofei; Wu, Shuting; Yuan, Yue; Cui, Linchong; Feng, Huiru; Lin, Danfan; Chen, Zilu; Lu, Juan; Peng, Xiaohong; Chen, Jing.

BMC Cancer ; 22(1): 1262, 2022 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-36471255

6.

Interactome Analysis of NS1 Protein Encoded by Influenza A H7N9 Virus Reveals an Inhibitory Role of NS1 in Host mRNA Maturation.

Kuo, Rei-Lin; Chen, Chi-Jene; Tam, Ee-Hong; Huang, Chung-Guei; Li, Li-Hsin; Li, Zong-Hua; Su, Pei-Chia; Liu, Hao-Ping; Wu, Chih-Ching.

J Proteome Res ; 17(4): 1474-1484, 2018 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-29558158

7.

Role of N Terminus-Truncated NS1 Proteins of Influenza A Virus in Inhibiting IRF3 Activation.

Kuo, Rei-Lin; Li, Li-Hsin; Lin, Sue-Jane; Li, Zong-Hua; Chen, Guang-Wu; Chang, Cheng-Kai; Wang, Yi-Ren; Tam, Ee-Hong; Gong, Yu-Nong; Krug, Robert M; Shih, Shin-Ru.

J Virol ; 90(9): 4696-4705, 2016 May.

Artigo em Inglês | MEDLINE | ID: mdl-26912617

8.

Interactome Analysis of the NS1 Protein Encoded by Influenza A H1N1 Virus Reveals a Positive Regulatory Role of Host Protein PRP19 in Viral Replication.

Kuo, Rei-Lin; Li, Zong-Hua; Li, Li-Hsin; Lee, Kuo-Ming; Tam, Ee-Hong; Liu, Helene M; Liu, Hao-Ping; Shih, Shin-Ru; Wu, Chih-Ching.

J Proteome Res ; 15(5): 1639-48, 2016 05 06.

Artigo em Inglês | MEDLINE | ID: mdl-27096427

9.

Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer's disease.

Raulin, Ana-Caroline; Doss, Sydney V; Heckman, Michael G; Craver, Emily C; Li, Zonghua; Ikezu, Tadafumi C; Sekiya, Hiroaki; Liu, Chia-Chen; Martens, Yuka A; Rosenberg, Cassandra L; Kuchenbecker, Lindsey A; DeTure, Michael; Reichard, R Ross; Nguyen, Aivi T; Constantopoulos, Eleni; Larsen, Rachel A; Kounaves, Emmaline K; Murray, Melissa E; Dickson, Dennis W; Petersen, Ronald C; Bu, Guojun; Kanekiyo, Takahisa.

Acta Neuropathol Commun ; 12(1): 25, 2024 Feb 09.

Artigo em Inglês | MEDLINE | ID: mdl-38336940

10.

Standardized immunoprecipitation protocol for efficient isolation of native apolipoprotein E particles utilizing HJ15.4 monoclonal antibody.

O'Leary, Justin; Raulin, Ana-Caroline; Li, Zonghua; Martens, Yuka; Inoue, Yasuteru; Strickland, Michael R; Han, Xianlin; Holtzman, David M; Bu, Guojun; Zhao, Na.

STAR Protoc ; 4(2): 102271, 2023 Jun 07.

Artigo em Inglês | MEDLINE | ID: mdl-37289593

11.

Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment.

Li, Zonghua; Heckman, Michael G; Kanekiyo, Takahisa; Martens, Yuka A; Day, Gregory S; Vassilaki, Maria; Liu, Chia-Chen; Bennett, David A; Petersen, Ronald C; Zhao, Na; Bu, Guojun.

Neurology ; 98(20): e2036-e2045, 2022 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-35314499

12.

Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.

Liu, Chia-Chen; Zhao, Jing; Fu, Yuan; Inoue, Yasuteru; Ren, Yingxue; Chen, Yuanxin; Doss, Sydney V; Shue, Francis; Jeevaratnam, Suren; Bastea, Ligia; Wang, Na; Martens, Yuka A; Qiao, Wenhui; Wang, Minghui; Zhao, Na; Jia, Lin; Yamazaki, Yu; Yamazaki, Akari; Rosenberg, Cassandra L; Wang, Zhen; Kong, Dehui; Li, Zonghua; Kuchenbecker, Lindsey A; Trottier, Zachary A; Felton, Lindsey; Rogers, Justin; Quicksall, Zachary S; Linares, Cynthia; Knight, Joshua; Chen, Yixing; Kurti, Aishe; Kanekiyo, Takahisa; Fryer, John D; Asmann, Yan W; Storz, Peter; Wang, Xusheng; Peng, Junmin; Zhang, Bin; Kim, Betty Y S; Bu, Guojun.

Nat Neurosci ; 25(8): 1020-1033, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-35915180

13.

Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia.

Zhao, Na; Qiao, Wenhui; Li, Fuyao; Ren, Yingxue; Zheng, Jiaying; Martens, Yuka A; Wang, Xusheng; Li, Ling; Liu, Chia-Chen; Chen, Kai; Zhu, Yiyang; Ikezu, Tadafumi C; Li, Zonghua; Meneses, Axel D; Jin, Yunjung; Knight, Joshua A; Chen, Yixing; Bastea, Ligia; Linares, Cynthia; Sonustun, Berkiye; Job, Lucy; Smith, Madeleine L; Xie, Manling; Liu, Yong U; Umpierre, Anthony D; Haruwaka, Koichiro; Quicksall, Zachary S; Storz, Peter; Asmann, Yan W; Wu, Long-Jun; Bu, Guojun.

J Exp Med ; 219(12)2022 12 05.

Artigo em Inglês | MEDLINE | ID: mdl-36107206

14.

Ear diseases among secondary school students in Xi'an, China: the role of portable audio device use, insomnia and academic stress.

Chen, Yang; Li, Xu; Xu, Zhan; Li, Zonghua; Zhang, Pengzhi; He, Ya; Wang, Fangyuan; Qiu, Jianhua.

BMC Public Health ; 11: 445, 2011 Jun 08.

Artigo em Inglês | MEDLINE | ID: mdl-21649930

15.

Deterioration characteristics of cement-improved loess under dry-wet and freeze-thaw cycles.

Jiang, Ying-Jun; Ni, Chen-Yang; Sha, Hong-Wei; Li, Zong-Hua; Cai, Lu-Yao.

PLoS One ; 16(7): e0253199, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34197469

16.

Long-term monitoring of dynamic changes in plasma EBV DNA for improved prognosis prediction of nasopharyngeal carcinoma.

Li, Wanxia; Chen, Jing; Liang, Bijun; Li, Zonghua; Li, Junzheng; Yuan, Xiaofei; Wu, Shuting; Zeng, Fangfang; Peng, Xinyu; Li, Yanfei; Lu, Juan; Zhao, Feipeng; Liu, Xiong.

Cancer Med ; 10(3): 883-894, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33378109

17.

Integrating pre- and post-treatment Plasma Epstein-Barr Virus DNA levels for better prognostic prediction of Nasopharyngeal Carcinoma.

Li, Wanxia; Yang, Chao; Lv, Zehong; Li, Junzheng; Li, Zonghua; Yuan, Xiaofei; Wu, Shuting; Yuan, Yue; Cui, Linchong; Lu, Juan; Chen, Jing; Zhao, Feipeng.

J Cancer ; 12(9): 2715-2722, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33854631

18.

APOE2: protective mechanism and therapeutic implications for Alzheimer's disease.

Li, Zonghua; Shue, Francis; Zhao, Na; Shinohara, Mitsuru; Bu, Guojun.

Mol Neurodegener ; 15(1): 63, 2020 11 04.

Artigo em Inglês | MEDLINE | ID: mdl-33148290

19.

Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.

Zhao, Na; Ren, Yingxue; Yamazaki, Yu; Qiao, Wenhui; Li, Fuyao; Felton, Lindsey M; Mahmoudiandehkordi, Siamak; Kueider-Paisley, Alexandra; Sonoustoun, Berkiye; Arnold, Matthias; Shue, Francis; Zheng, Jiaying; Attrebi, Olivia N; Martens, Yuka A; Li, Zonghua; Bastea, Ligia; Meneses, Axel D; Chen, Kai; Thompson, J Will; St John-Williams, Lisa; Tachibana, Masaya; Aikawa, Tomonori; Oue, Hiroshi; Job, Lucy; Yamazaki, Akari; Liu, Chia-Chen; Storz, Peter; Asmann, Yan W; Ertekin-Taner, Nilüfer; Kanekiyo, Takahisa; Kaddurah-Daouk, Rima; Bu, Guojun.

Neuron ; 106(5): 727-742.e6, 2020 06 03.

Artigo em Inglês | MEDLINE | ID: mdl-32199103

20.

A water pill against Alzheimer's disease.

Li, Zonghua; Zhao, Na.

Nat Aging ; 1(10): 868-869, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-37118331

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