Detalhe da pesquisa
1.
Understanding the molecular mechanisms of statin pleiotropic effects.
Arch Toxicol
; 97(6): 1529-1545, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37084080
2.
Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
Stroke
; 50(3): 738-744, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30744543
3.
Pleiotropic Effects of Statins on the Cardiovascular System.
Circ Res
; 120(1): 229-243, 2017 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28057795
4.
The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.
Am J Respir Cell Mol Biol
; 58(4): 471-481, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29211497
5.
Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice.
Circ J
; 82(4): 1195-1204, 2018 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29353861
6.
The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis.
Pharmacol Rev
; 67(1): 103-17, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25395505
7.
Challenging Statin Pleiotropy: Preeclampsia.
Circulation
; 144(9): 680-683, 2021 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34460319
8.
Elevated Angiopoietin-2 Level in Patients With Continuous-Flow Left Ventricular Assist Devices Leads to Altered Angiogenesis and Is Associated With Higher Nonsurgical Bleeding.
Circulation
; 134(2): 141-52, 2016 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27354285
9.
RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
Stroke
; 48(1): 187-194, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27879448
10.
Rho Kinases and Cardiac Remodeling.
Circ J
; 80(7): 1491-8, 2016 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27251065
11.
Two functional polymorphisms of ROCK2 enhance arterial stiffening through inhibiting its activity and expression.
J Mol Cell Cardiol
; 79: 180-6, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25481646
12.
ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice.
Am J Physiol Lung Cell Mol Physiol
; 309(7): L736-46, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26276827
13.
Abrogation of airway hyperresponsiveness but not inflammation by rho kinase insufficiency.
Clin Exp Allergy
; 45(2): 457-70, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25323425
14.
Interventional Transcatheter Closure Ameliorates the Leukocyte Rho Kinase Activities among Patients with Patent Ductus Arteriosus.
Acta Cardiol Sin
; 31(6): 494-9, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27122913
15.
Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.
Clin Sci (Lond)
; 126(12): 829-835, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24351102
16.
FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.
FASEB J
; 27(4): 1439-49, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23271052
17.
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Arterioscler Thromb Vasc Biol
; 33(7): 1591-600, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23640485
18.
Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations.
Neurol Genet
; 10(1): e200121, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38179414
19.
Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis.
Circulation
; 126(18): 2236-47, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23011471
20.
Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis.
Hum Mol Genet
; 20(12): 2344-55, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21447599