Detalhe da pesquisa
1.
Multi-omics links IL-6 trans-signalling with neutrophil extracellular trap formation and Haemophilus infection in COPD.
Eur Respir J
; 58(4)2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33766947
2.
A class of highly selective inhibitors bind to an active state of PI3Kγ.
Nat Chem Biol
; 15(4): 348-357, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718815
3.
Discovery of triazole aminopyrazines as a highly potent and selective series of PI3Kδ inhibitors.
Bioorg Med Chem Lett
; 27(3): 679-687, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28017532
4.
Discovery of AZD8154, a Dual PI3Kγδ Inhibitor for the Treatment of Asthma.
J Med Chem
; 64(12): 8053-8075, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34080862
5.
A Comparative Study of Fluorescence Assays in Screening for BRD4.
Assay Drug Dev Technol
; 16(7): 372-383, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30307314
6.
Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3-Kinase (PI3K)-γ Inhibitors.
J Med Chem
; 61(12): 5435-5441, 2018 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29852070
7.
Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration.
J Med Chem
; 60(12): 5057-5071, 2017 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28520415
8.
Inhibition of intestinal bile acid transporter Slc10a2 improves triglyceride metabolism and normalizes elevated plasma glucose levels in mice.
PLoS One
; 7(5): e37787, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22662222
9.
Gene expression profiling shows that macrophages derived from mouse embryonic stem cells is an improved in vitro model for studies of vascular disease.
Exp Cell Res
; 300(2): 335-44, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15474998