Detalhe da pesquisa
1.
Sub-setting systemic lupus erythematosus by combined molecular phenotypes defines divergent populations in two phase III randomized trials.
Rheumatology (Oxford)
; 60(11): 5390-5396, 2021 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33580248
2.
Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 2 trial.
Lancet
; 392(10143): 222-231, 2018 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30043749
3.
Clinical trial parameters that influence outcomes in lupus trials that use the systemic lupus erythematosus responder index.
Rheumatology (Oxford)
; 57(1): 125-133, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045736
4.
B- and T-Lymphocyte Attenuator in Systemic Lupus Erythematosus Disease Pathogenesis.
Clin Pharmacol Ther
; 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38676311
5.
Laser Capture Microscopy RNA Sequencing for Topological Mapping of Synovial Pathology During Rheumatoid Arthritis.
Arthritis Rheumatol
; 2024 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38556917
6.
A nondepleting anti-CD19 antibody impairs B cell function and inhibits autoimmune diseases.
JCI Insight
; 8(13)2023 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37427592
7.
Evaluation of the safety of rituximab in combination with a tumor necrosis factor inhibitor and methotrexate in patients with active rheumatoid arthritis: results from a randomized controlled trial.
Arthritis Rheum
; 63(3): 622-32, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21360491
8.
Target modulation and pharmacokinetics/pharmacodynamics translation of the BTK inhibitor poseltinib for model-informed phase II dose selection.
Sci Rep
; 11(1): 18671, 2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34548595
9.
Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity.
J Pharmacol Exp Ther
; 324(2): 867-75, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17993604
10.
Pharmacokinetics of high-dose abetimus sodium in normal subjects with specific assessment of effect on coagulation.
J Clin Pharmacol
; 48(8): 909-18, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18511650
11.
Gene Expression and Pharmacodynamic Changes in 1,760 Systemic Lupus Erythematosus Patients From Two Phase III Trials of BAFF Blockade With Tabalumab.
Arthritis Rheumatol
; 69(3): 643-654, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27723281
12.
Design, synthesis, and biological evaluation of semicarbazide-sensitive amine oxidase (SSAO) inhibitors with anti-inflammatory activity.
J Med Chem
; 49(7): 2166-73, 2006 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16570912
13.
Therapeutic potential of toleragens in the management of antiphospholipid syndrome.
BioDrugs
; 18(5): 297-305, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15377172
14.
Advances in understanding what we measure when detecting anticardiolipin autoantibodies.
Clin Chim Acta
; 343(1-2): 37-44, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15115676
15.
In vivo characterization of bioconjugate B cell toleragens with specificity for autoantibodies in antiphospholipid syndrome.
Int Immunopharmacol
; 3(12): 1667-75, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14555291
16.
Abetimus sodium for renal flare in systemic lupus erythematosus: results of a randomized, controlled phase III trial.
Arthritis Rheum
; 58(8): 2470-80, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18668592
17.
Vascular adhesion protein-1 plays an important role in postischemic inflammation and neuropathology in diabetic, estrogen-treated ovariectomized female rats subjected to transient forebrain ischemia.
J Pharmacol Exp Ther
; 317(1): 19-29, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16339390
18.
Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V.
Arthritis Rheum
; 54(8): 2558-67, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16868978
19.
Relationship between anti-double-stranded DNA antibodies and exacerbation of renal disease in patients with systemic lupus erythematosus.
Arthritis Rheum
; 52(4): 1129-37, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15818711
20.
Domain V of beta2-glycoprotein I binds factor XI/XIa and is cleaved at Lys317-Thr318.
J Biol Chem
; 280(2): 907-12, 2005 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15522884