Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model.

Chen, Yefei; Hong, Zexuan; Wang, Jingyi; Liu, Kunlin; Liu, Jing; Lin, Jianbang; Feng, Shijing; Zhang, Tianhui; Shan, Liang; Liu, Taian; Guo, Pinyue; Lin, Yunping; Li, Tian; Chen, Qian; Jiang, Xiaodan; Li, Anan; Li, Xiang; Li, Yuantao; Wilde, Jonathan J; Bao, Jin; Dai, Ji; Lu, Zhonghua.

Cell ; 186(24): 5394-5410.e18, 2023 11 22.

Artigo em Inglês | MEDLINE | ID: mdl-37922901

2.

Founder cells shape brain evolution.

Liu, Jing; Silver, Debra L.

Cell ; 184(8): 1965-1967, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33861961

3.

Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.

Lu, Sydney X; De Neef, Emma; Thomas, James D; Sabio, Erich; Rousseau, Benoit; Gigoux, Mathieu; Knorr, David A; Greenbaum, Benjamin; Elhanati, Yuval; Hogg, Simon J; Chow, Andrew; Ghosh, Arnab; Xie, Abigail; Zamarin, Dmitriy; Cui, Daniel; Erickson, Caroline; Singer, Michael; Cho, Hana; Wang, Eric; Lu, Bin; Durham, Benjamin H; Shah, Harshal; Chowell, Diego; Gabel, Austin M; Shen, Yudao; Liu, Jing; Jin, Jian; Rhodes, Matthew C; Taylor, Richard E; Molina, Henrik; Wolchok, Jedd D; Merghoub, Taha; Diaz, Luis A; Abdel-Wahab, Omar; Bradley, Robert K.

Cell ; 184(15): 4032-4047.e31, 2021 07 22.

Artigo em Inglês | MEDLINE | ID: mdl-34171309

4.

Large-Scale Comparative Analyses of Tick Genomes Elucidate Their Genetic Diversity and Vector Capacities.

Jia, Na; Wang, Jinfeng; Shi, Wenqiang; Du, Lifeng; Sun, Yi; Zhan, Wei; Jiang, Jia-Fu; Wang, Qian; Zhang, Bing; Ji, Peifeng; Bell-Sakyi, Lesley; Cui, Xiao-Ming; Yuan, Ting-Ting; Jiang, Bao-Gui; Yang, Wei-Fei; Lam, Tommy Tsan-Yuk; Chang, Qiao-Cheng; Ding, Shu-Jun; Wang, Xian-Jun; Zhu, Jin-Guo; Ruan, Xiang-Dong; Zhao, Lin; Wei, Jia-Te; Ye, Run-Ze; Que, Teng Cheng; Du, Chun-Hong; Zhou, Yu-Hao; Cheng, Jing Xia; Dai, Pei-Fang; Guo, Wen-Bin; Han, Xiao-Hu; Huang, En-Jiong; Li, Lian-Feng; Wei, Wei; Gao, Yu-Chi; Liu, Jing-Ze; Shao, Hong-Ze; Wang, Xin; Wang, Chong-Cai; Yang, Tian-Ci; Huo, Qiu-Bo; Li, Wei; Chen, Hai-Ying; Chen, Shen-En; Zhou, Ling-Guo; Ni, Xue-Bing; Tian, Jun-Hua; Sheng, Yue; Liu, Tao; Pan, Yu-Sheng.

Cell ; 182(5): 1328-1340.e13, 2020 09 03.

Artigo em Inglês | MEDLINE | ID: mdl-32814014

5.

Structural Basis of Smoothened Activation in Hedgehog Signaling.

Huang, Pengxiang; Zheng, Sanduo; Wierbowski, Bradley M; Kim, Youngchang; Nedelcu, Daniel; Aravena, Laura; Liu, Jing; Kruse, Andrew C; Salic, Adrian.

Cell ; 174(2): 312-324.e16, 2018 07 12.

Artigo em Inglês | MEDLINE | ID: mdl-29804838

6.

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.

Huang, Pengxiang; Nedelcu, Daniel; Watanabe, Miyako; Jao, Cindy; Kim, Youngchang; Liu, Jing; Salic, Adrian.

Cell ; 166(5): 1176-1187.e14, 2016 Aug 25.

Artigo em Inglês | MEDLINE | ID: mdl-27545348

7.

The ER membrane adaptor ERAdP senses the bacterial second messenger c-di-AMP and initiates anti-bacterial immunity.

Xia, Pengyan; Wang, Shuo; Xiong, Zhen; Zhu, Xiaoxiao; Ye, Buqing; Du, Ying; Meng, Shu; Qu, Yuan; Liu, Jing; Gao, Guangxia; Tian, Yong; Fan, Zusen.

Nat Immunol ; 19(2): 141-150, 2018 02.

Artigo em Inglês | MEDLINE | ID: mdl-29292386

8.

A dedicated hypothalamic oxytocin circuit controls aversive social learning.

Osakada, Takuya; Yan, Rongzhen; Jiang, Yiwen; Wei, Dongyu; Tabuchi, Rina; Dai, Bing; Wang, Xiaohan; Zhao, Gavin; Wang, Clara Xi; Liu, Jing-Jing; Tsien, Richard W; Mar, Adam C; Lin, Dayu.

Nature ; 626(7998): 347-356, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38267576

9.

Phylogenomics and the rise of the angiosperms.

Zuntini, Alexandre R; Carruthers, Tom; Maurin, Olivier; Bailey, Paul C; Leempoel, Kevin; Brewer, Grace E; Epitawalage, Niroshini; Françoso, Elaine; Gallego-Paramo, Berta; McGinnie, Catherine; Negrão, Raquel; Roy, Shyamali R; Simpson, Lalita; Toledo Romero, Eduardo; Barber, Vanessa M A; Botigué, Laura; Clarkson, James J; Cowan, Robyn S; Dodsworth, Steven; Johnson, Matthew G; Kim, Jan T; Pokorny, Lisa; Wickett, Norman J; Antar, Guilherme M; DeBolt, Lucinda; Gutierrez, Karime; Hendriks, Kasper P; Hoewener, Alina; Hu, Ai-Qun; Joyce, Elizabeth M; Kikuchi, Izai A B S; Larridon, Isabel; Larson, Drew A; de Lírio, Elton John; Liu, Jing-Xia; Malakasi, Panagiota; Przelomska, Natalia A S; Shah, Toral; Viruel, Juan; Allnutt, Theodore R; Ameka, Gabriel K; Andrew, Rose L; Appelhans, Marc S; Arista, Montserrat; Ariza, María Jesús; Arroyo, Juan; Arthan, Watchara; Bachelier, Julien B; Bailey, C Donovan; Barnes, Helen F.

Nature ; 2024 Apr 24.

Artigo em Inglês | MEDLINE | ID: mdl-38658746

10.

Reducing brassinosteroid signalling enhances grain yield in semi-dwarf wheat.

Song, Long; Liu, Jie; Cao, Beilu; Liu, Bin; Zhang, Xiaoping; Chen, Zhaoyan; Dong, Chaoqun; Liu, Xiangqing; Zhang, Zhaoheng; Wang, Wenxi; Chai, Lingling; Liu, Jing; Zhu, Jun; Cui, Shubin; He, Fei; Peng, Huiru; Hu, Zhaorong; Su, Zhenqi; Guo, Weilong; Xin, Mingming; Yao, Yingyin; Yan, Yong; Song, Yinming; Bai, Guihua; Sun, Qixin; Ni, Zhongfu.

Nature ; 617(7959): 118-124, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37100915

11.

Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA.

Jonas, Kristina; Liu, Jing; Chien, Peter; Laub, Michael T.

Cell ; 154(3): 623-36, 2013 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-23911325

12.

Structural Basis of Smoothened Activation in Hedgehog Signaling.

Huang, Pengxiang; Zheng, Sanduo; Wierbowski, Bradley M; Kim, Youngchang; Nedelcu, Daniel; Aravena, Laura; Liu, Jing; Kruse, Andrew C; Salic, Adrian.

Cell ; 175(1): 295-297, 2018 09 20.

Artigo em Inglês | MEDLINE | ID: mdl-30241610

13.

Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation.

Yan, Jie; Xiang, Jialing; Lin, Yutin; Ma, Jingui; Zhang, Jiyan; Zhang, Hao; Sun, Jisheng; Danial, Nika N; Liu, Jing; Lin, Anning.

Cell ; 152(1-2): 304-15, 2013 Jan 17.

Artigo em Inglês | MEDLINE | ID: mdl-23332762

14.

NLRs guard metabolism to coordinate pattern- and effector-triggered immunity.

Zhai, Keran; Liang, Di; Li, Helin; Jiao, Fangyuan; Yan, Bingxiao; Liu, Jing; Lei, Ziyao; Huang, Li; Gong, Xiangyu; Wang, Xin; Miao, Jiashun; Wang, Yichuan; Liu, Ji-Yun; Zhang, Lin; Wang, Ertao; Deng, Yiwen; Wen, Chi-Kuang; Guo, Hongwei; Han, Bin; He, Zuhua.

Nature ; 601(7892): 245-251, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34912119

15.

TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly.

Yao, Weijing; Chen, Yuting; Chen, Yingcong; Zhao, Pengwei; Liu, Jing; Zhang, Yi; Jiang, Qiang; Wu, Choufei; Xie, Yu; Fan, Siyu; Ye, Miao; Wang, Yigang; Feng, Yuyao; Bai, Xue; Fan, Mingzhu; Feng, Shan; Wang, Juan; Cui, Yixian; Xia, Hongguang; Ma, Cheng; Xie, Zhiping; Zhang, Liqin; Sun, Qiming; Liu, Wei; Yi, Cong.

EMBO J ; 42(19): e112814, 2023 10 04.

Artigo em Inglês | MEDLINE | ID: mdl-37635626

16.

Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma.

Che, Huiwen; Jiang, Peiyong; Choy, L Y Lois; Cheng, Suk Hang; Peng, Wenlei; Chan, Rebecca W Y; Liu, Jing; Zhou, Qing; Lam, W K Jacky; Yu, Stephanie C Y; Lau, So Ling; Leung, Tak Y; Wong, John; Wong, Vincent Wai-Sun; Wong, Grace L H; Chan, Stephen L; Chan, K C Allen; Lo, Y M Dennis.

Genome Res ; 34(2): 189-200, 2024 Mar 20.

Artigo em Inglês | MEDLINE | ID: mdl-38408788

17.

The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation.

Zhang, Qiao; Kuang, Hong; Chen, Cong; Yan, Jie; Do-Umehara, Hanh Chi; Liu, Xin-yuan; Dada, Laura; Ridge, Karen M; Chandel, Navdeep S; Liu, Jing.

Nat Immunol ; 16(5): 458-66, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25799126

18.

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.

Deng, Meihong; Tang, Yiting; Li, Wenbo; Wang, Xiangyu; Zhang, Rui; Zhang, Xianying; Zhao, Xin; Liu, Jian; Tang, Cheng; Liu, Zhonghua; Huang, Yongzhuo; Peng, Huige; Xiao, Lehui; Tang, Daolin; Scott, Melanie J; Wang, Qingde; Liu, Jing; Xiao, Xianzhong; Watkins, Simon; Li, Jianhua; Yang, Huan; Wang, Haichao; Chen, Fangping; Tracey, Kevin J; Billiar, Timothy R; Lu, Ben.

Immunity ; 49(4): 740-753.e7, 2018 10 16.

Artigo em Inglês | MEDLINE | ID: mdl-30314759

19.

Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression.

Yu, Dongbo; Pendergraff, Hannah; Liu, Jing; Kordasiewicz, Holly B; Cleveland, Don W; Swayze, Eric E; Lima, Walt F; Crooke, Stanley T; Prakash, Thazha P; Corey, David R.

Cell ; 150(5): 895-908, 2012 Aug 31.

Artigo em Inglês | MEDLINE | ID: mdl-22939619

20.

Structure, function and pharmacology of human itch GPCRs.

Cao, Can; Kang, Hye Jin; Singh, Isha; Chen, He; Zhang, Chengwei; Ye, Wenlei; Hayes, Byron W; Liu, Jing; Gumpper, Ryan H; Bender, Brian J; Slocum, Samuel T; Krumm, Brian E; Lansu, Katherine; McCorvy, John D; Kroeze, Wesley K; English, Justin G; DiBerto, Jeffrey F; Olsen, Reid H J; Huang, Xi-Ping; Zhang, Shicheng; Liu, Yongfeng; Kim, Kuglae; Karpiak, Joel; Jan, Lily Y; Abraham, Soman N; Jin, Jian; Shoichet, Brian K; Fay, Jonathan F; Roth, Bryan L.

Nature ; 600(7887): 170-175, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34789874

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Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model.

Founder cells shape brain evolution.

Pharmacologic modulation of RNA splicing enhances anti-tumor immunity.

Large-Scale Comparative Analyses of Tick Genomes Elucidate Their Genetic Diversity and Vector Capacities.

Structural Basis of Smoothened Activation in Hedgehog Signaling.

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.

The ER membrane adaptor ERAdP senses the bacterial second messenger c-di-AMP and initiates anti-bacterial immunity.

A dedicated hypothalamic oxytocin circuit controls aversive social learning.

Phylogenomics and the rise of the angiosperms.

Reducing brassinosteroid signalling enhances grain yield in semi-dwarf wheat.

Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA.

Structural Basis of Smoothened Activation in Hedgehog Signaling.

Inactivation of BAD by IKK inhibits TNFα-induced apoptosis independently of NF-κB activation.

NLRs guard metabolism to coordinate pattern- and effector-triggered immunity.

TOR-mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly.

Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma.

The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation.

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis.

Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression.

Structure, function and pharmacology of human itch GPCRs.