[Role of eukaryotic translation initiation factor 4G in tumor].

Eukaryotic translation initiation factor 4G (eIF4G) is a scaffold component of eukaryotic translation initiation factor 4F (eIF4F) complex, which takes principal part in the initiating of protein synthesis. Both two subtypes (eIF4G1 and eIF4G2) of eIF4G were found to be closely related with various tumors. The eIF4G1 expression is significantly up-regulated in breast cancer, cervical cancer, nasopharyngeal carcinoma, lung squamous cell carcinoma, prostatic carcinoma and other malignant tumors, compared with those in adjacent tissues; and the eIF4G2 is obviously over-expressed in diffuse large B cell lymphoma and acute myeloid leukemia, but low-expressed in bladder transitional cell carcinoma. This paper reviews the progress in the study of the role of eIF4G in tumor genesis, development, diagnosis and prognosis.

[Influence of superfine grinding technology on extracting flavones from plantain].

OBJECTIVE: To study the influence of superfine grinding technology on extracting flavones from plantain and explore its optimum extraction technology. METHODS: Ultrasonic technology was used to extract the flavones in superfine grinding plantain, the content of flavone glycosides was determined by RP-HPLC. RESULTS: The optimum technology was as follows: the concentration of ethanol was 60%, temperature was 60 degrees C, solid-liquid ratio (g:mL) was 1:20 and extraction time was 20 min. Under these conditions, flavonoids extraction rate of superfine grinding powder was higher than that of conventional powder. CONCLUSION: The technology of superfine grinding can improve flavonoids extraction rate in plantain. An optimum method for extracting flavonoids from superfine granding plantain is established.