Detalhe da pesquisa
1.
SPG15 protein deficits are at the crossroads between lysosomal abnormalities, altered lipid metabolism and synaptic dysfunction.
Hum Mol Genet
; 31(16): 2693-2710, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35313342
2.
Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length.
J Neurosci
; 41(38): 7954-7964, 2021 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34341156
3.
An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.
Acta Neuropathol
; 144(3): 437-464, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35876881
4.
Dysregulation of AMPA receptor subunit expression in sporadic ALS post-mortem brain.
J Pathol
; 250(1): 67-78, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31579943
5.
Reversal of proliferation deficits caused by chromosome 16p13.11 microduplication through targeting NFκB signaling: an integrated study of patient-derived neuronal precursor cells, cerebral organoids and in vivo brain imaging.
Mol Psychiatry
; 24(2): 294-311, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30401811
6.
Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction.
Mol Psychiatry
; 24(11): 1641-1654, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31481758
7.
Myelinated axon physiology and regulation of neural circuit function.
Glia
; 67(11): 2050-2062, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31233642
8.
Maturation and electrophysiological properties of human pluripotent stem cell-derived oligodendrocytes.
Stem Cells
; 34(4): 1040-53, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26763608
9.
Functional properties of in vitro excitatory cortical neurons derived from human pluripotent stem cells.
J Physiol
; 594(22): 6573-6582, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26608229
10.
Maturation of AMPAR composition and the GABAAR reversal potential in hPSC-derived cortical neurons.
J Neurosci
; 34(11): 4070-5, 2014 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24623784
11.
Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones.
J Physiol
; 592(19): 4353-63, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25172951
12.
Mutagenic analysis of the intracellular portals of the human 5-HT3A receptor.
J Biol Chem
; 288(44): 31592-601, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24030822
13.
Importin 13-dependent axon diameter growth regulates conduction speeds along myelinated CNS axons.
Nat Commun
; 15(1): 1790, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38413580
14.
Rings of charge within the extracellular vestibule influence ion permeation of the 5-HT3A receptor.
J Biol Chem
; 286(18): 16008-17, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21454663
15.
3-Fluoro-N-methyl-D-aspartic acid (3F-NMDA) stereoisomers as conformational probes for exploring agonist binding at NMDA receptors.
Chemistry
; 18(28): 8813-9, 2012 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22692769
16.
Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis.
Neuron
; 110(6): 992-1008.e11, 2022 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35045337
17.
Emerging Mechanisms Underpinning Neurophysiological Impairments in C9ORF72 Repeat Expansion-Mediated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
Front Cell Neurosci
; 15: 784833, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34975412
18.
Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction.
Mol Neurodegener
; 16(1): 13, 2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33663561
19.
SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis.
Mol Neurodegener
; 16(1): 53, 2021 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34376242
20.
Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model.
Brain Commun
; 3(4): fcab255, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35350711