Detalhe da pesquisa
1.
Functional genomic landscape of acute myeloid leukaemia.
Nature
; 562(7728): 526-531, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333627
2.
Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia.
Proc Natl Acad Sci U S A
; 117(25): 14331-14341, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513686
3.
CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells.
Blood
; 133(6): 588-599, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30425048
4.
Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression.
Blood
; 125(3): 504-15, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25370416
5.
SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia.
Haematologica
; 102(11): 1890-1900, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28838991
6.
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.
N Engl J Med
; 368(19): 1781-90, 2013 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23656643
7.
BCR-ABL1 promotes leukemia by converting p27 into a cytoplasmic oncoprotein.
Blood
; 124(22): 3260-73, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25293778
8.
Aurora A kinase as a target for therapy in TCF3-HLF rearranged acute lymphoblastic leukemia.
Haematologica
; 106(11): 2990-2994, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34233449
9.
Mast cell sarcoma with concurrent mast cell leukaemia.
Br J Haematol
; 189(4): e160-e164, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32242922
10.
The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.
Blood
; 122(22): 3628-31, 2013 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24081659
11.
Identification of driver and passenger mutations of FLT3 by high-throughput DNA sequence analysis and functional assessment of candidate alleles.
Cancer Cell
; 12(6): 501-13, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18068628
12.
HitWalker: variant prioritization for personalized functional cancer genomics.
Bioinformatics
; 29(4): 509-10, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23303510
13.
Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML.
Blood
; 120(13): 2658-68, 2012 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22889761
14.
Activating alleles of JAK3 in acute megakaryoblastic leukemia.
Cancer Cell
; 10(1): 65-75, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16843266
15.
TSLP signaling network revealed by SILAC-based phosphoproteomics.
Mol Cell Proteomics
; 11(6): M112.017764, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22345495
16.
The selective SYK inhibitor P505-15 (PRT062607) inhibits B cell signaling and function in vitro and in vivo and augments the activity of fludarabine in chronic lymphocytic leukemia.
J Pharmacol Exp Ther
; 344(2): 378-87, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23220742
17.
CAL-101, a p110delta selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability.
Blood
; 117(2): 591-4, 2011 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959606
18.
TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms.
Blood
; 118(24): 6392-8, 2011 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21860020
19.
A case study of personalized therapy for osteosarcoma.
Pediatr Blood Cancer
; 60(8): 1313-9, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23526721
20.
An adaptive Src-PDGFRA-Raf axis in rhabdomyosarcoma.
Biochem Biophys Res Commun
; 426(3): 363-8, 2012 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22960170