Detalhe da pesquisa
1.
An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells.
Cell
; 182(4): 1009-1026.e29, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32730809
2.
A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells.
Cell
; 161(7): 1668-80, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26091042
3.
Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron.
Nat Chem Biol
; 19(12): 1469-1479, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37349583
4.
ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.
Nat Chem Biol
; 17(8): 856-864, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33927411
5.
Proteome-wide covalent ligand discovery in native biological systems.
Nature
; 534(7608): 570-4, 2016 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27309814
6.
Chemoproteomics-Enabled Identification of 4-Oxo-ß-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Angew Chem Int Ed Engl
; 61(47): e202210498, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36089535
7.
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
J Biol Chem
; 295(18): 5891-5905, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152231
8.
Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.
Nat Chem Biol
; 15(5): 453-462, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30911178
9.
Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors.
J Am Chem Soc
; 138(49): 15841-15844, 2016 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27960302
10.
Chemical Proteomic Profiling of Human Methyltransferases.
J Am Chem Soc
; 138(40): 13335-13343, 2016 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27689866
11.
Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host.
Cell Chem Biol
; 28(10): 1501-1513.e5, 2021 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34043961
12.
3-Oxo-ß-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling.
ACS Chem Biol
; 15(4): 878-883, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32176480
13.
Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator.
Cell Rep
; 31(12): 107805, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32579931
14.
Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics.
ACS Chem Biol
; 12(10): 2671-2681, 2017 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28930429
15.
Multicomponent mapping of boron chemotypes furnishes selective enzyme inhibitors.
Nat Commun
; 8(1): 1760, 2017 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29170371
16.
An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.
Cancer Cell
; 30(5): 683-693, 2016 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27746144
17.
Stabilized Wittig olefination for bioconjugation.
Chem Commun (Camb)
; 49(95): 11188-90, 2013 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24150718
18.
Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates.
Chem Biol
; 19(5): 579-88, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22542104