Detalhe da pesquisa
1.
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function.
Pharmacol Rev
; 73(1): 310-520, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33370241
2.
Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site.
J Biol Chem
; 297(2): 100899, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157288
3.
Snake venom phospholipase A2s exhibit strong virucidal activity against SARS-CoV-2 and inhibit the viral spike glycoprotein interaction with ACE2.
Cell Mol Life Sci
; 78(23): 7777-7794, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34714362
4.
Multiple regions in the extracellular domain of the glycine receptor determine receptor activity.
J Biol Chem
; 293(36): 13889-13896, 2018 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941455
5.
Identification of Novel Functionally Important Aromatic Residue Interactions in the Extracellular Domain of the Glycine Receptor.
Biochemistry
; 57(27): 4029-4035, 2018 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29947514
6.
Probing Proline Residues in the Prokaryotic Ligand-Gated Ion Channel, ELIC.
Biochemistry
; 57(27): 4036-4043, 2018 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29927250
7.
Modeling and Mutational Analysis of the Binding Mode for the Multimodal Antidepressant Drug Vortioxetine to the Human 5-HT3A Receptor.
Mol Pharmacol
; 94(6): 1421-1434, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30257860
8.
The roles of aromatic residues in the glycine receptor transmembrane domain.
BMC Neurosci
; 19(1): 53, 2018 Sep 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30189850
9.
The Proton Responsiveness in the Extracellular Domain of GLIC Differs in the Presence of the ELIC Transmembrane Domain.
Biochemistry
; 56(15): 2134-2138, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28383883
10.
Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors.
J Biol Chem
; 291(12): 6272-80, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26668320
11.
Disturbed neuronal ER-Golgi sorting of unassembled glycine receptors suggests altered subcellular processing is a cause of human hyperekplexia.
J Neurosci
; 35(1): 422-37, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25568133
12.
Crotonic Acid Blocks the Gloeobacter Ligand-Gated Ion Channel (GLIC) via the Extracellular Domain.
Biochemistry
; 55(42): 5947-5951, 2016 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27739668
13.
Probing residues in the pore-forming (M2) domain of the Cys-loop receptor homologue GLIC reveals some unusual features.
Mol Membr Biol
; 32(1): 26-31, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25865129
14.
Structural basis of ligand recognition in 5-HT3 receptors.
EMBO Rep
; 14(1): 49-56, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23196367
15.
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines.
Proc Natl Acad Sci U S A
; 109(44): E3028-34, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035248
16.
Phenylalanine in the pore of the Erwinia ligand-gated ion channel modulates picrotoxinin potency but not receptor function.
Biochemistry
; 53(39): 6183-8, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25238029
17.
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
J Biol Chem
; 288(12): 8355-8364, 2013 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23364792
18.
Insights into the binding of GABA to the insect RDL receptor from atomistic simulations: a comparison of models.
J Comput Aided Mol Des
; 28(1): 35-48, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24442887
19.
Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT3 receptors.
Nat Struct Mol Biol
; 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38698207
20.
5-HT(3) receptors.
J Biol Chem
; 287(48): 40239-45, 2012 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23038271