Detalhe da pesquisa
1.
Discovery of benzo[d]oxazol-2(3H)-one derivatives as a new class of TNIK inhibitors for the treatment of colorectal cancer.
Bioorg Med Chem Lett
; 67: 128745, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447345
2.
Neutrophil Extracellular Traps (NETs) Are Associated with Type 2 Diabetes and Diabetic Foot Ulcer Related Amputation: A Prospective Cohort Study.
Diabetes Ther
; 15(6): 1333-1348, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38619692
3.
Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.
J Med Chem
; 65(3): 1786-1807, 2022 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34985886
4.
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.
Nat Commun
; 13(1): 6891, 2022 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36371441
5.
Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.
J Med Chem
; 65(3): 2035-2058, 2022 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35080890