Detalhe da pesquisa
1.
PD-1 and TIGIT downregulation distinctly affect the effector and early memory phenotypes of CD19-targeting CAR T cells.
Mol Ther
; 30(2): 579-592, 2022 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34628052
2.
Switchable control over in vivo CAR T expansion, B cell depletion, and induction of memory.
Proc Natl Acad Sci U S A
; 115(46): E10898-E10906, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30373813
3.
Versatile strategy for controlling the specificity and activity of engineered T cells.
Proc Natl Acad Sci U S A
; 113(4): E450-8, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26759368
4.
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer.
Angew Chem Int Ed Engl
; 55(26): 7520-4, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27145250
5.
Redirection of genetically engineered CAR-T cells using bifunctional small molecules.
J Am Chem Soc
; 137(8): 2832-5, 2015 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25692571
6.
Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers.
Angew Chem Int Ed Engl
; 54(24): 7022-7, 2015 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25919418
7.
Ganglioside inhibition of CD8+ T cell cytotoxicity: interference with lytic granule trafficking and exocytosis.
J Immunol
; 189(7): 3521-7, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22956583
8.
A PSMA-targeted bispecific antibody for prostate cancer driven by a small-molecule targeting ligand.
Sci Adv
; 7(33)2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34380625
9.
Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity.
J Immunol
; 181(7): 4716-22, 2008 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18802074
10.
Activation of primary T lymphocytes results in lysosome development and polarized granule exocytosis in CD4+ and CD8+ subsets, whereas expression of lytic molecules confers cytotoxicity to CD8+ T cells.
J Leukoc Biol
; 80(4): 827-37, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16891618
11.
Gangliosides drive the tumor infiltration and function of myeloid-derived suppressor cells.
Cancer Res
; 74(19): 5449-57, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25115301
12.
Protein kinase Cdelta regulates antigen receptor-induced lytic granule polarization in mouse CD8+ CTL.
J Immunol
; 178(12): 7814-21, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17548619