Detalhe da pesquisa
1.
Discovery of 4-phenyl-1H-indazole derivatives as novel small-molecule inhibitors targeting the PD-1/PD-L1 interaction.
Bioorg Chem
; 147: 107376, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38640722
2.
Design, synthesis, and bioevaluation of imidazo [1,2-a] pyrazine derivatives as tubulin polymerization inhibitors with potent anticancer activities.
Bioorg Med Chem
; 76: 117098, 2022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36455508
3.
Discovery of Novel Potent and Fast BTK PROTACs for the Treatment of Osteoclasts-Related Inflammatory Diseases.
J Med Chem
; 67(4): 2438-2465, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38321747
4.
Discovery of Ibrutinib-based BTK PROTACs with in vivo anti-inflammatory efficacy by inhibiting NF-κB activation.
Eur J Med Chem
; 259: 115664, 2023 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487306
5.
Discovery of pomalidomide-based PROTACs for selective degradation of histone deacetylase 8.
Eur J Med Chem
; 239: 114544, 2022 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35759908