Detalhe da pesquisa
1.
Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10.
J Biol Chem
; 298(12): 102552, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36183834
2.
Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.
Proc Natl Acad Sci U S A
; 114(1): 136-141, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27980032
3.
An epoxide hydrolase secreted by Pseudomonas aeruginosa decreases mucociliary transport and hinders bacterial clearance from the lung.
Am J Physiol Lung Cell Mol Physiol
; 314(1): L150-L156, 2018 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28982736
4.
The CFTR trafficking mutation F508del inhibits the constitutive activity of SLC26A9.
Am J Physiol Lung Cell Mol Physiol
; 312(6): L912-L925, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28360110
5.
Optimization of the process of inverted peptides (PIPEPLUS) to screen PDZ domain ligands.
Bioorg Med Chem Lett
; 27(14): 3111-3116, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28549735
6.
Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif.
Biochemistry
; 55(5): 788-97, 2016 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26752215
7.
Serum- and glucocorticoid-induced protein kinase 1 (SGK1) increases the cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells by phosphorylating Shank2E protein.
J Biol Chem
; 289(24): 17142-50, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24811177
8.
Signature motifs identify an Acinetobacter Cif virulence factor with epoxide hydrolase activity.
J Biol Chem
; 289(11): 7460-9, 2014 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24474692
9.
A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch.
J Am Chem Soc
; 137(26): 8435-49, 2015 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26038984
10.
Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity.
Angew Chem Int Ed Engl
; 54(20): 5874-8, 2015 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25785567
11.
Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR.
Angew Chem Int Ed Engl
; 54(34): 9881-5, 2015 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26136396
12.
Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop.
J Biol Chem
; 288(7): 5114-26, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23243314
13.
Reconstitution of homomeric GluA2(flop) receptors in supported lipid membranes: functional and structural properties.
J Biol Chem
; 288(12): 8647-8657, 2013 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382380
14.
Structural basis for c-di-GMP-mediated inside-out signaling controlling periplasmic proteolysis.
PLoS Biol
; 9(2): e1000588, 2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21304926
15.
Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa.
bioRxiv
; 2024 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38293063
16.
Disabled-2 protein facilitates assembly polypeptide-2-independent recruitment of cystic fibrosis transmembrane conductance regulator to endocytic vesicles in polarized human airway epithelial cells.
J Biol Chem
; 287(18): 15087-99, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22399289
17.
Correction to "A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch".
J Am Chem Soc
; 140(12): 4466, 2018 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29553265
18.
Computational design of a PDZ domain peptide inhibitor that rescues CFTR activity.
PLoS Comput Biol
; 8(4): e1002477, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22532795
19.
Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets.
Protein Sci
; 32(4): e4611, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36851847
20.
Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets.
bioRxiv
; 2023 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36711692