Detalhe da pesquisa
1.
Downregulation of ABCC3 activates MAPK signaling through accumulation of deoxycholic acid in colorectal cancer cells.
Cancer Sci
; 115(6): 1778-1790, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38566304
2.
Analysis of Metabolic Changes in Endogenous Metabolites and Diagnostic Biomarkers for Various Diseases Using Liquid Chromatography and Mass Spectrometry.
Biol Pharm Bull
; 47(6): 1087-1105, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38825462
3.
Wide-Targeted Semi-Quantitative Analysis of Acidic Glycosphingolipids in Cell Lines and Urine to Develop Potential Screening Biomarkers for Renal Cell Carcinoma.
Int J Mol Sci
; 25(7)2024 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38612906
4.
The Use of an Antioxidant Enables Accurate Evaluation of the Interaction of Curcumin on Organic Anion-Transporting Polypeptides 4C1 by Preventing Auto-Oxidation.
Int J Mol Sci
; 25(2)2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38256064
5.
Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity.
Drug Metab Dispos
; 51(2): 165-173, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36414408
6.
Functional Characterization of 29 Cytochrome P450 4F2 Variants Identified in a Population of 8380 Japanese Subjects and Assessment of Arachidonic Acid ω-Hydroxylation.
Drug Metab Dispos
; 51(12): 1561-1568, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37775333
7.
Development of a Simultaneous Liquid Chromatography-Tandem Mass Spectrometry Analytical Method for Urinary Endogenous Substrates and Metabolites for Predicting Cytochrome P450 3A4 Activity.
Biol Pharm Bull
; 46(3): 455-463, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36858575
8.
Therapeutic Drug Monitoring of Blood Sirolimus and Tacrolimus Concentrations for Polypharmacy Management in a Lymphangioleiomyomatosis Patient Taking Two Cytochrome P450 3A Inhibitors.
Tohoku J Exp Med
; 260(1): 29-34, 2023 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36858510
9.
Global Proteomics for Identifying the Alteration Pathway of Niemann-Pick Disease Type C Using Hepatic Cell Models.
Int J Mol Sci
; 24(21)2023 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37958627
10.
Predictive model for recurrence of renal cell carcinoma by comparing pre- and postoperative urinary metabolite concentrations.
Cancer Sci
; 113(1): 182-194, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34710258
11.
Evaluation of a Capillary Microsampling Device for Analyzing Plasma Lenvatinib Concentration in Patients With Hepatocellular Carcinoma.
Ther Drug Monit
; 44(6): 771-776, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35863065
12.
Development of a Highly Sensitive and Rapid Liquid Chromatography-Tandem Mass Spectrometric Method Using a Basic Mobile Phase Additive to Determine the Characteristics of the Urinary Metabolites for Niemann-Pick Disease Type C.
Biol Pharm Bull
; 45(9): 1259-1268, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36047194
13.
Cutting-edge LC-MS/MS applications in clinical mass spectrometry: Focusing on analysis of drugs and metabolites.
Biomed Chromatogr
; 36(5): e5347, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35073598
14.
Prolonged high-intensity exercise induces fluctuating immune responses to herpes simplex virus infection via glucocorticoids.
J Allergy Clin Immunol
; 148(6): 1575-1588.e7, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33965431
15.
Bile Acid-Drug Interaction via Organic Anion-Transporting Polypeptide 4C1 Is a Potential Mechanism of Altered Pharmacokinetics of Renally Excreted Drugs.
Int J Mol Sci
; 23(15)2022 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35955643
16.
Metabolic Alteration Analysis of Steroid Hormones in Niemann-Pick Disease Type C Model Cell Using Liquid Chromatography/Tandem Mass Spectrometry.
Int J Mol Sci
; 23(8)2022 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35457276
17.
Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6ß-Hydroxylation.
Drug Metab Dispos
; 49(3): 212-220, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33384383
18.
Role of OATP4C1 in Renal Handling of Remdesivir and its Nucleoside Analog GS-441524: The First Approved Drug for Patients with COVID-19.
J Pharm Pharm Sci
; 24: 227-236, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34048668
19.
High-throughput liquid chromatography/electrospray ionization-tandem mass spectrometry method using in-source collision-induced dissociation for simultaneous quantification of imatinib, dasatinib, bosutinib, nilotinib, and ibrutinib in human plasma.
Biomed Chromatogr
; 35(8): e5124, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33772839
20.
Simultaneous analysis of drugs administered to lung-transplanted patients using liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring.
Biomed Chromatogr
; 35(6): e5067, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33450064