Detalhe da pesquisa
1.
Layered immunity and layered leukemogenicity: Developmentally restricted mechanisms of pediatric leukemia initiation.
Immunol Rev
; 315(1): 197-215, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36588481
2.
Disruption of polyunsaturated fatty acid biosynthesis drives STING-dependent acute myeloid leukemia cell maturation and death.
J Biol Chem
; 300(5): 107214, 2024 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38522521
3.
FLT3ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation.
Blood
; 141(12): 1442-1456, 2023 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36395068
4.
Macrophage NOX2 NADPH oxidase maintains alveolar homeostasis in mice.
Blood
; 139(19): 2855-2870, 2022 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35357446
5.
Haematopoietic stem cells require a highly regulated protein synthesis rate.
Nature
; 509(7498): 49-54, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24670665
6.
Sleepwalking stem cells.
Blood
; 129(14): 1887-1888, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28385766
7.
Basal type I interferon signaling has only modest effects on neonatal and juvenile hematopoiesis.
Blood Adv
; 7(11): 2609-2621, 2023 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724510
8.
Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.
Clin Cancer Res
; 29(22): 4613-4626, 2023 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37725576
9.
Comment on: Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia.
Br J Haematol
; 176(1): 5-6, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27766614
10.
Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation.
Cancer Cell
; 3(3): 273-83, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12676585
11.
Single-cell RNA transcriptome analysis of CNS immune cells reveals CXCL16/CXCR6 as maintenance factors for tissue-resident T cells that drive synapse elimination.
Genome Med
; 14(1): 108, 2022 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36153630
12.
A somatic mutation in moesin drives progression into acute myeloid leukemia.
Sci Adv
; 8(16): eabm9987, 2022 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35442741
13.
Transcriptional reprogramming in neonatal hematopoietic stem and progenitor cells.
Exp Hematol
; 101-102: 25-33, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34303776
14.
Developmental Stage-Specific Changes in Protein Synthesis Differentially Sensitize Hematopoietic Stem Cells and Erythroid Progenitors to Impaired Ribosome Biogenesis.
Stem Cell Reports
; 16(1): 20-28, 2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33440178
15.
Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy.
Cell Rep
; 34(7): 108751, 2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33596429
16.
Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium.
Cancer Discov
; 11(6): 1424-1439, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33563661
17.
Single-Cell Analysis of Neonatal HSC Ontogeny Reveals Gradual and Uncoordinated Transcriptional Reprogramming that Begins before Birth.
Cell Stem Cell
; 27(5): 732-747.e7, 2020 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32822583
18.
TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS.
Exp Hematol
; 88: 42-55, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32652111
19.
LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression.
Leukemia
; 38(3): 648-651, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38321106
20.
The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development.
Blood Adv
; 3(15): 2388-2399, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31405949