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J Virol Methods ; 165(1): 105-7, 2010 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-20043952

RESUMO

UNLABELLED: We evaluated the sensitivity for the anti-HIV antibody detection of the 8 rapid disposable tests (RDTs) EC approved in 2008. METHODS: A panel of 100 native serum samples collected from HIV-1 subtype B or non-B, HIV-1 group O or HIV-2-infected patient and 3 commercial seroconversion panels were tested. 50 sera from HIV-negative patients were included to blind reading and RDT specificity. RESULTS: All native samples HIV-1 subtype B were reactive; an HIV-1 non-B subtype gave false-negative results with 3 of the 8 tests. False-negative results on HIV-1 group O samples were observed with one RDT. All the HIV-2 samples were detected. Seroconversion sample reactivity ranged from 60 to 86.7% according to the tests. CONCLUSION: Despite their lower performances relative to ELISA tests during the HIV seroconversion period, RDT may be of interest in case of chronic infection.


Assuntos
Técnicas de Laboratório Clínico/métodos , Anticorpos Anti-HIV/sangue , Infecções por HIV/diagnóstico , HIV-1/imunologia , HIV-2/imunologia , União Europeia , Reações Falso-Negativas , Soropositividade para HIV , Humanos , Imunoensaio/métodos , Sensibilidade e Especificidade
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