Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

The Role of Endoplasmic Reticulum in Lipotoxicity during Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Pathogenesis.

Venkatesan, Nanditha; Doskey, Luke C; Malhi, Harmeet.

Am J Pathol ; 193(12): 1887-1899, 2023 12.

Artigo em Inglês | MEDLINE | ID: mdl-37689385

2.

Emerging targets for therapy in ALD: Lessons from NASH.

Singal, Ashwani K; Shah, Vijay H; Malhi, Harmeet.

Hepatology ; 2023 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-36938877

3.

Endoplasmic reticulum stress in liver diseases.

Ajoolabady, Amir; Kaplowitz, Neil; Lebeaupin, Cynthia; Kroemer, Guido; Kaufman, Randal J; Malhi, Harmeet; Ren, Jun.

Hepatology ; 77(2): 619-639, 2023 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-35524448

4.

Adding Inflammatory Markers and Refining National Institute on Alcohol Abuse and Alcoholism Criteria Improve Diagnostic Accuracy for Alcohol-associated Hepatitis.

Avitabile, Emma; Díaz, Alba; Montironi, Carla; Pérez-Guasch, Martina; Gratacós-Ginès, Jordi; Hernández-Évole, Helena; Moreira, Roger K; Sehrawat, Tejasav S; Malhi, Harmeet; Olivas, Pol; Hernández-Gea, Virginia; Bataller, Ramón; Shah, Vijay H; Kamath, Patrick S; Ginès, Pere; Pose, Elisa.

Clin Gastroenterol Hepatol ; 21(12): 3080-3088.e9, 2023 11.

Artigo em Inglês | MEDLINE | ID: mdl-37004974

5.

Circulating Extracellular Vesicles Carrying Sphingolipid Cargo for the Diagnosis and Dynamic Risk Profiling of Alcoholic Hepatitis.

Sehrawat, Tejasav S; Arab, Juan P; Liu, Mengfei; Amrollahi, Pouya; Wan, Meihua; Fan, Jia; Nakao, Yasuhiko; Pose, Elisa; Navarro-Corcuera, Amaia; Dasgupta, Debanjali; Liao, Chieh-Yu; He, Li; Mauer, Amy S; Avitabile, Emma; Ventura-Cots, Meritxell; Bataller, Ramon A; Sanyal, Arun J; Chalasani, Naga P; Heimbach, Julie K; Watt, Kymberly D; Gores, Gregory J; Gines, Pere; Kamath, Patrick S; Simonetto, Douglas A; Hu, Tony Y; Shah, Vijay H; Malhi, Harmeet.

Hepatology ; 73(2): 571-585, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-32246544

6.

Evaluation of a PEGylated Fibroblast Growth Factor 21 Variant Using Novel Preclinical Magnetic Resonance Imaging and Magnetic Resonance Elastography in a Mouse Model of Nonalcoholic Steatohepatitis.

Tang, Haiying; Li, Jiahui; Zinker, Bradley; Boehm, Stephanie; Mauer, Amy; Rex-Rabe, Sandra; Glaser, Kevin J; Fronheiser, Matthew; Bradstreet, Thomas; Nakao, Yasuhiko; Petrone, Thomas; Pena, Adrienne; Villano, MacKenzie; Chow, Patrick; Malhi, Harmeet; Charles, Edgar D; Hayes, Wendy; Ehman, Richard L; Du, Shuyan; Yin, Meng.

J Magn Reson Imaging ; 56(3): 712-724, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35092323

7.

Coordinated signaling of activating transcription factor 6α and inositol-requiring enzyme 1α regulates hepatic stellate cell-mediated fibrogenesis in mice.

Xue, Fei; Lu, Jianwen; Buchl, Samuel C; Sun, Liankang; Shah, Vijay H; Malhi, Harmeet; Maiers, Jessica L.

Am J Physiol Gastrointest Liver Physiol ; 320(5): G864-G879, 2021 05 01.

Artigo em Inglês | MEDLINE | ID: mdl-33728997

8.

IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis.

Dasgupta, Debanjali; Nakao, Yasuhiko; Mauer, Amy S; Thompson, Jill M; Sehrawat, Tejasav S; Liao, Chieh-Yu; Krishnan, Anuradha; Lucien, Fabrice; Guo, Qianqian; Liu, Mengfei; Xue, Fei; Fukushima, Masanori; Katsumi, Tomohiro; Bansal, Aditya; Pandey, Mukesh K; Maiers, Jessica L; DeGrado, Timothy; Ibrahim, Samar H; Revzin, Alexander; Pavelko, Kevin D; Barry, Michael A; Kaufman, Randal J; Malhi, Harmeet.

Gastroenterology ; 159(4): 1487-1503.e17, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32574624

9.

Efficacy and Safety of Endoscopic Balloon Placement for Weight Loss in Patients With Cirrhosis Awaiting Liver Transplantation.

Watt, Kymberly D; Heimbach, Julie K; Rizk, Monika; Jaruvongvanich, Pete; Sanchez, William; Port, John; Venkatesh, Sudhakar K; Bamlet, Heather; Tiedtke, Kathryn; Malhi, Harmeet; Acosta Cardenas, Andres; Grothe, Karen; Clark, Matthew; Mundi, Manpreet S; Abu Dayyeh, Barham K.

Liver Transpl ; 27(9): 1239-1247, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-33866660

10.

An Open-Label, Dose-Escalation Study to Assess the Safety and Efficacy of IL-22 Agonist F-652 in Patients With Alcohol-associated Hepatitis.

Arab, Juan P; Sehrawat, Tejasav S; Simonetto, Douglas A; Verma, Vikas K; Feng, Dechun; Tang, Tom; Dreyer, Kevin; Yan, Xiaoqiang; Daley, William L; Sanyal, Arun; Chalasani, Naga; Radaeva, Svetlana; Yang, Liu; Vargas, Hugo; Ibacache, Mauricio; Gao, Bin; Gores, Gregory J; Malhi, Harmeet; Kamath, Patrick S; Shah, Vijay H.

Hepatology ; 72(2): 441-453, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-31774566

11.

Circulating extracellular vesicles are a biomarker for NAFLD resolution and response to weight loss surgery.

Nakao, Yasuhiko; Amrollahi, Pouya; Parthasarathy, Gopanandan; Mauer, Amy S; Sehrawat, Tejasav S; Vanderboom, Patrick; Nair, K Sreekumaran; Nakao, Kazuhiko; Allen, Alina M; Hu, Tony Y; Malhi, Harmeet.

Nanomedicine ; 36: 102430, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34174416

12.

Nonalcoholic Steatohepatitis Promoting Kinases.

Ibrahim, Samar H; Hirsova, Petra; Malhi, Harmeet; Gores, Gregory J.

Semin Liver Dis ; 40(4): 346-357, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32526787

13.

Transforming growth factor ß (TGFß) cross-talk with the unfolded protein response is critical for hepatic stellate cell activation.

Liu, Zhikui; Li, Chao; Kang, Ningling; Malhi, Harmeet; Shah, Vijay H; Maiers, Jessica L.

J Biol Chem ; 294(9): 3137-3151, 2019 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-30610118

14.

Manuscript best practices: Takeaways from a community conversation.

Wong, Carmen Chak-Lui; Tapper, Elliot B; Malhi, Harmeet; Gores, Gregory J.

Hepatology ; 79(6): 1243-1245, 2024 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-38466823

15.

Endoplasmic Reticulum Stress in Metabolic Liver Diseases and Hepatic Fibrosis.

Maiers, Jessica L; Malhi, Harmeet.

Semin Liver Dis ; 39(2): 235-248, 2019 May.

Artigo em Inglês | MEDLINE | ID: mdl-30912096

16.

StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis.

Fukushima, Masanori; Dasgupta, Debanjali; Mauer, Amy S; Kakazu, Eiji; Nakao, Kazuhiko; Malhi, Harmeet.

J Biol Chem ; 293(39): 15277-15289, 2018 09 28.

Artigo em Inglês | MEDLINE | ID: mdl-30139741

17.

Emerging role of extracellular vesicles in liver diseases.

Malhi, Harmeet.

Am J Physiol Gastrointest Liver Physiol ; 317(5): G739-G749, 2019 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-31545919

18.

Detection of DNA damage response in nonalcoholic fatty liver disease via p53-binding protein 1 nuclear expression.

Akazawa, Yuko; Nakashima, Ryoma; Matsuda, Katsuya; Okamaoto, Koji; Hirano, Ran; Kawasaki, Hiroko; Miuma, Satoshi; Miyaaki, Hisamitsu; Malhi, Harmeet; Abiru, Seigo; Itoh, Masahiro; Kondo, Hisayohi; Fukuoka, Junya; Nakao, Kazuhiko; Nakashima, Masahiro.

Mod Pathol ; 32(7): 997-1007, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30809000

19.

What is Hepatology looking for version 2.0?

Malhi, Harmeet; Gores, Gregory J.

Hepatology ; 77(3): 707-708, 2023 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-35753067

20.

Letters to the Editor: defining utility and pertinence.