Detalhe da pesquisa
1.
Another One Fights the Dust: Targeting the NLRP3 Inflammasome for the Treatment of Silicosis.
Am J Respir Cell Mol Biol
; 66(6): 601-611, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35290170
2.
Interleukin-1ß exacerbates disease and is a potential therapeutic target to reduce pulmonary inflammation during severe influenza A virus infection.
Immunol Cell Biol
; 99(7): 737-748, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33834544
3.
The Single Nucleotide Polymorphism Mal-D96N Mice Provide New Insights into Functionality of Mal in TLR Immune Responses.
J Immunol
; 202(8): 2384-2396, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30787108
4.
Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling.
Proc Natl Acad Sci U S A
; 114(32): E6480-E6489, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28739909
5.
A type III effector antagonizes death receptor signalling during bacterial gut infection.
Nature
; 501(7466): 247-51, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24025841
6.
PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome.
J Biol Chem
; 292(3): 826-836, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913620
7.
Membrane vesicles from Pseudomonas aeruginosa activate the noncanonical inflammasome through caspase-5 in human monocytes.
Immunol Cell Biol
; 96(10): 1120-1130, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30003588
8.
Sculpting the immune response to infection.
Nat Immunol
; 12(7): 579-82, 2011 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21685948
9.
The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages.
FASEB J
; 31(1): 85-95, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27682204
10.
BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs.
Proc Natl Acad Sci U S A
; 112(5): 1535-40, 2015 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605927
11.
Porphyromonas gulae Activates Unprimed and Gamma Interferon-Primed Macrophages via the Pattern Recognition Receptors Toll-Like Receptor 2 (TLR2), TLR4, and NOD2.
Infect Immun
; 85(9)2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28630066
12.
Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension.
Pharmacol Res
; 116: 77-86, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27986554
13.
Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses.
Proc Natl Acad Sci U S A
; 111(7): 2650-5, 2014 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24481253
14.
Induction of memory cytotoxic T cells to influenza A virus and subsequent viral clearance is not modulated by PB1-F2-dependent inflammasome activation.
Immunol Cell Biol
; 94(5): 439-46, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26667784
15.
HIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1.
J Virol
; 89(13): 6575-84, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25855743
16.
Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB.
J Biol Chem
; 289(2): 654-68, 2014 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24265315
17.
Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
J Biol Chem
; 289(10): 6429-6437, 2014 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24407287
18.
Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease.
PLoS Pathog
; 9(5): e1003392, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23737748
19.
Innate IL-17A-producing leukocytes promote acute kidney injury via inflammasome and Toll-like receptor activation.
Am J Pathol
; 184(5): 1411-8, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24631024
20.
Recombinant production of functional full-length and truncated human TRAM/TICAM-2 adaptor protein involved in Toll-like receptor and interferon signaling.
Protein Expr Purif
; 106: 31-40, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25306876