Detalhe da pesquisa
1.
A systematic review on disease-drug-drug interactions with immunomodulating drugs: A critical appraisal of risk assessment and drug labelling.
Br J Clin Pharmacol
; 88(10): 4387-4402, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484780
2.
IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways.
J Allergy Clin Immunol
; 145(3): 808-817.e2, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31805312
3.
Mannitol triggers mast cell-dependent contractions of human small bronchi and prostacyclin bronchoprotection.
J Allergy Clin Immunol
; 144(4): 984-992, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31207273
4.
Long-Acting ß2-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)-Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR.
Mol Pharmacol
; 94(3): 1031-1046, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29959223
5.
Human lung natural killer cells are predominantly comprised of highly differentiated hypofunctional CD69-CD56dim cells.
J Allergy Clin Immunol
; 139(4): 1321-1330.e4, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27670241
6.
The TLR7 agonist imiquimod induces bronchodilation via a nonneuronal TLR7-independent mechanism: a possible role for quinoline in airway dilation.
Am J Physiol Lung Cell Mol Physiol
; 310(11): L1121-9, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27084847
7.
Prostaglandin E2 inhibits mast cell-dependent bronchoconstriction in human small airways through the E prostanoid subtype 2 receptor.
J Allergy Clin Immunol
; 136(5): 1232-9.e1, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25962903
8.
CNS Viral Infections-What to Consider for Improving Drug Treatment: A Plea for Using Mathematical Modeling Approaches.
CNS Drugs
; 38(5): 349-373, 2024 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38580795
9.
Unraveling the Effects of Acute Inflammation on Pharmacokinetics: A Model-Based Analysis Focusing on Renal Glomerular Filtration Rate and Cytochrome P450 3A4-Mediated Metabolism.
Eur J Drug Metab Pharmacokinet
; 48(6): 623-631, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37715056
10.
The impact of CYP2C19 genotype on phenoconversion by concomitant medication.
Front Pharmacol
; 14: 1201906, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37361233
11.
The bitter taste receptor (TAS2R) agonists denatonium and chloroquine display distinct patterns of relaxation of the guinea pig trachea.
Am J Physiol Lung Cell Mol Physiol
; 303(11): L956-66, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22962016
12.
PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice.
Sci Rep
; 12(1): 483, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013582
13.
The bronchodilatory capacity of imiquimod: the existence of two mechanisms.
Am J Physiol Lung Cell Mol Physiol
; 311(1): L178-9, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27407080
14.
Distinct Effects of Inflammation on Cytochrome P450 Regulation and Drug Metabolism: Lessons from Experimental Models and a Potential Role for Pharmacogenetics.
Genes (Basel)
; 11(12)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33339226
15.
Phenoconversion of Cytochrome P450 Metabolism: A Systematic Review.
J Clin Med
; 9(9)2020 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32906709
16.
Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle.
Eur J Pharmacol
; 740: 302-11, 2014 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25036266
17.
[Demethylating medication in myelodysplastic syndrome]. / Demethylerende medicatie bij myelodysplastisch syndroom: epigenetica als target voor therapie.
Ned Tijdschr Geneeskd
; 156(4): A3167, 2012.
Artigo
em Holandês
| MEDLINE | ID: mdl-22278034