Detalhe da pesquisa
1.
Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation.
N Engl J Med
; 376(6): 536-547, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28177873
2.
The relative utilities of genome-wide, gene panel, and individual gene sequencing in clinical practice.
Blood
; 130(4): 433-439, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28600338
3.
The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia.
Blood
; 129(4): 497-508, 2017 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27756750
4.
SETD2 alterations impair DNA damage recognition and lead to resistance to chemotherapy in leukemia.
Blood
; 130(24): 2631-2641, 2017 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29018079
5.
Age-related clonal hematopoiesis associated with adverse outcomes.
N Engl J Med
; 371(26): 2488-98, 2014 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25426837
6.
Acute myeloid leukemia ontogeny is defined by distinct somatic mutations.
Blood
; 125(9): 1367-76, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25550361
7.
CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.
Nature
; 459(7249): 1000-4, 2009 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19536265
8.
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Cancer Discov
; 14(2): 240-257, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37916956
9.
Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.
Clin Cancer Res
; 29(22): 4613-4626, 2023 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37725576
10.
Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial.
Nat Med
; 27(12): 2183-2191, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34873347
11.
Efficacy and safety of avapritinib in advanced systemic mastocytosis: interim analysis of the phase 2 PATHFINDER trial.
Nat Med
; 27(12): 2192-2199, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34873345
12.
Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.
J Clin Oncol
; 35(14): 1598-1605, 2017 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28068180
13.
Membrane-associated and secreted genes in breast cancer.
Cancer Res
; 64(23): 8682-7, 2004 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15574777
14.
Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia.
J Clin Invest
; 126(10): 3827-3836, 2016 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27599292
15.
Somatic mutations predict poor outcome in patients with myelodysplastic syndrome after hematopoietic stem-cell transplantation.
J Clin Oncol
; 32(25): 2691-8, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092778
16.
Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia.
Nat Commun
; 5: 3469, 2014 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24662245
17.
Self-renewal related signaling in myeloid leukemia stem cells.
Int J Hematol
; 94(2): 109-117, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21800073
18.
Novel transcription factors in human CD34 antigen-positive hematopoietic cells.
Blood
; 100(1): 107-19, 2002 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12070015