Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

WIPIng the Brakes off Autophagy Induction.

Marsh, Timothy; Debnath, Jayanta.

Mol Cell ; 72(2): 203-204, 2018 10 18.

Artigo em Inglês | MEDLINE | ID: mdl-30340019

2.

Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival.

Yang, Yang; Gomez, Maria; Marsh, Timothy; Poillet-Perez, Laura; Sawant, Akshada; Chen, Lei; Park, Noel R; Jackson, S RaElle; Hu, Zhixian; Alon, Noa; Liu, Chen; Debnath, Jayanta; Guan, Jun-Lin; Davidson, Shawn; Verzi, Michael; White, Eileen.

Proc Natl Acad Sci U S A ; 119(21): e2202016119, 2022 05 24.

Artigo em Inglês | MEDLINE | ID: mdl-35537042

3.

The pleiotropic functions of autophagy in metastasis.

Marsh, Timothy; Tolani, Bhairavi; Debnath, Jayanta.

J Cell Sci ; 134(2)2021 01 22.

Artigo em Inglês | MEDLINE | ID: mdl-33483365

4.

Fibroblasts as architects of cancer pathogenesis.

Marsh, Timothy; Pietras, Kristian; McAllister, Sandra S.

Biochim Biophys Acta ; 1832(7): 1070-8, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23123598

5.

Secretory autophagy maintains proteostasis upon lysosome inhibition.

Solvik, Tina A; Nguyen, Tan A; Tony Lin, Yu-Hsiu; Marsh, Timothy; Huang, Eric J; Wiita, Arun P; Debnath, Jayanta; Leidal, Andrew M.

J Cell Biol ; 221(6)2022 06 06.

Artigo em Inglês | MEDLINE | ID: mdl-35446347

6.

Homonegativity and its relationship to religiosity, nationalism and attachment style.

Marsh, Timothy; Brown, Jac.

J Relig Health ; 50(3): 575-91, 2011 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-19830564

7.

Autophagy suppresses breast cancer metastasis by degrading NBR1.

Marsh, Timothy; Debnath, Jayanta.

Autophagy ; 16(6): 1164-1165, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32267786

8.

Ribosome profiling reveals a functional role for autophagy in mRNA translational control.

Goldsmith, Juliet; Marsh, Timothy; Asthana, Saurabh; Leidal, Andrew M; Suresh, Deepthisri; Olshen, Adam; Debnath, Jayanta.

Commun Biol ; 3(1): 388, 2020 07 17.

Artigo em Inglês | MEDLINE | ID: mdl-32681145

9.

Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.

Marsh, Timothy; Kenific, Candia M; Suresh, Deepthisri; Gonzalez, Hugo; Shamir, Eliah R; Mei, Wenbin; Tankka, Alexandra; Leidal, Andrew M; Kalavacherla, Sandhya; Woo, Kimberly; Werb, Zena; Debnath, Jayanta.

Dev Cell ; 52(5): 591-604.e6, 2020 03 09.

Artigo em Inglês | MEDLINE | ID: mdl-32084360

10.

The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles.

Leidal, Andrew M; Huang, Hector H; Marsh, Timothy; Solvik, Tina; Zhang, Dachuan; Ye, Jordan; Kai, FuiBoon; Goldsmith, Juliet; Liu, Jennifer Y; Huang, Yu-Hsin; Monkkonen, Teresa; Vlahakis, Ariadne; Huang, Eric J; Goodarzi, Hani; Yu, Li; Wiita, Arun P; Debnath, Jayanta.

Nat Cell Biol ; 22(2): 187-199, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31932738

11.

Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer.

Adams, Christina R; Htwe, Htet Htwe; Marsh, Timothy; Wang, Aprilgate L; Montoya, Megan L; Subbaraj, Lakshmipriya; Tward, Aaron D; Bardeesy, Nabeel; Perera, Rushika M.

Elife ; 82019 05 28.

Artigo em Inglês | MEDLINE | ID: mdl-31134896

12.

Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression.

Marsh, Timothy; Wong, Irene; Sceneay, Jaclyn; Barakat, Amey; Qin, Yuanbo; Sjödin, Andreas; Alspach, Elise; Nilsson, Björn; Stewart, Sheila A; McAllister, Sandra S.

Cancer Res ; 76(10): 2932-43, 2016 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-27197230

13.

Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment.

Starobinets, Hanna; Ye, Jordan; Broz, Miranda; Barry, Kevin; Goldsmith, Juliet; Marsh, Timothy; Rostker, Fanya; Krummel, Matthew; Debnath, Jayanta.

J Clin Invest ; 126(12): 4417-4429, 2016 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-27775547

14.

Ironing out VPS34 inhibition.

Marsh, Timothy; Debnath, Jayanta.

Nat Cell Biol ; 17(1): 1-3, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25679028

15.

p38MAPK plays a crucial role in stromal-mediated tumorigenesis.

Alspach, Elise; Flanagan, Kevin C; Luo, Xianmin; Ruhland, Megan K; Huang, Hui; Pazolli, Ermira; Donlin, Maureen J; Marsh, Timothy; Piwnica-Worms, David; Monahan, Joseph; Novack, Deborah V; McAllister, Sandra S; Stewart, Sheila A.

Cancer Discov ; 4(6): 716-29, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24670723

16.

Stromal EGF and igf-I together modulate plasticity of disseminated triple-negative breast tumors.

Castaño, Zafira; Marsh, Timothy; Tadipatri, Ramya; Kuznetsov, Hanna S; Al-Shahrour, Fatima; Paktinat, Mahnaz; Greene-Colozzi, April; Nilsson, Björn; Richardson, Andrea L; McAllister, Sandra S.

Cancer Discov ; 3(8): 922-35, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23689072

17.

Identification of luminal breast cancers that establish a tumor-supportive macroenvironment defined by proangiogenic platelets and bone marrow-derived cells.

Kuznetsov, Hanna S; Marsh, Timothy; Markens, Beth A; Castaño, Zafira; Greene-Colozzi, April; Hay, Samantha A; Brown, Victoria E; Richardson, Andrea L; Signoretti, Sabina; Battinelli, Elisabeth M; McAllister, Sandra S.

Cancer Discov ; 2(12): 1150-65, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22896036

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WIPIng the Brakes off Autophagy Induction.

Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival.

The pleiotropic functions of autophagy in metastasis.

Fibroblasts as architects of cancer pathogenesis.

Secretory autophagy maintains proteostasis upon lysosome inhibition.

Homonegativity and its relationship to religiosity, nationalism and attachment style.

Autophagy suppresses breast cancer metastasis by degrading NBR1.

Ribosome profiling reveals a functional role for autophagy in mRNA translational control.

Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression.

The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles.

Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer.

Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression.

Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment.

Ironing out VPS34 inhibition.

p38MAPK plays a crucial role in stromal-mediated tumorigenesis.

Stromal EGF and igf-I together modulate plasticity of disseminated triple-negative breast tumors.

Identification of luminal breast cancers that establish a tumor-supportive macroenvironment defined by proangiogenic platelets and bone marrow-derived cells.