Detalhe da pesquisa
1.
Assessment of tumor necrotic fraction by dynamic contrast-enhanced MRI: a preclinical study of human tumor xenografts with histopathologic correlation.
NMR Biomed
; 27(4): 486-94, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24535773
2.
Preparation of [18F]-N-(2-fluoro-ethyl)-N-methylamine as a building block for PET radiopharmaceuticals.
J Labelled Comp Radiopharm
; 57(13): 715-20, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25347957
3.
Cinpanemab in Early Parkinson Disease: Evaluation of Biomarker Results From the Phase 2 SPARK Clinical Trial.
Neurology
; 102(5): e209137, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38315945
4.
Development of a Novel [11C]CO-Labeled Positron Emission Tomography Radioligand [11C]BIO-1819578 for the Detection of O-GlcNAcase Enzyme Activity.
ACS Chem Neurosci
; 14(14): 2560-2568, 2023 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37377046
5.
A Visual Interpretation Algorithm for Assessing Brain Tauopathy with 18F-MK-6240 PET.
J Nucl Med
; 64(3): 444-451, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36175137
6.
Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain.
J Nucl Med
; 64(10): 1588-1593, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37934021
7.
Exploratory Tau Biomarker Results From a Multiple Ascending-Dose Study of BIIB080 in Alzheimer Disease: A Randomized Clinical Trial.
JAMA Neurol
; 80(12): 1344-1352, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37902726
8.
Non-invasive Imaging of Antisense Oligonucleotides in the Brain via In Vivo Click Chemistry.
Mol Imaging Biol
; 24(6): 940-949, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35655109
9.
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease.
Sci Transl Med
; 14(658): eabk1051, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35976998
10.
Microfluidic reactions using [11C]carbon monoxide solutions for the synthesis of a positron emission tomography radiotracer.
Org Biomol Chem
; 9(9): 3313-9, 2011 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21437342
11.
Test-retest characteristic of [18F]MK-6240 quantitative outcomes in cognitively normal adults and subjects with Alzheimer's disease.
J Cereb Blood Flow Metab
; 40(11): 2179-2187, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31711342
12.
Copper(I) scorpionate complexes and their application in palladium-mediated [(11)C]carbonylation reactions.
Chem Commun (Camb)
; (25): 3696-8, 2009 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19557252
13.
Structural Basis for Achieving GSK-3ß Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery.
J Med Chem
; 62(21): 9600-9617, 2019 11 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31535859
14.
Molecular imaging in oncology drug development.
Drug Discov Today
; 22(1): 140-147, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693713
15.
Fluorinase mediated C-(18)F bond formation, an enzymatic tool for PET labelling.
Chem Commun (Camb)
; (6): 652-4, 2006 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16446840
16.
Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 (N-fluoroalkyl) labeled 2beta-carbomethoxy-3beta-(4'-(3-furyl)phenyl)tropanes and -nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography.
J Med Chem
; 48(22): 7080-3, 2005 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16250668
17.
Intravoxel incoherent imaging of renal fibrosis induced in a murine model of unilateral ureteral obstruction.
Magn Reson Imaging
; 33(10): 1324-1328, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26248270
18.
Human Kinetic Modeling of the 5HT6 PET Radioligand 11C-GSK215083 and Its Utility for Determining Occupancy at Both 5HT6 and 5HT2A Receptors by SB742457 as a Potential Therapeutic Mechanism of Action in Alzheimer Disease.
J Nucl Med
; 56(12): 1901-9, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26383152
19.
Radiolabeled amino acids for tumor imaging with PET: radiosynthesis and biological evaluation of 2-amino-3-[18F]fluoro-2-methylpropanoic acid and 3-[18F]fluoro-2-methyl-2-(methylamino)propanoic acid.
J Med Chem
; 45(11): 2240-9, 2002 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12014962
20.
Synthesis of syn- and anti-1-amino-3-[18F]fluoromethyl-cyclobutane-1-carboxylic acid (FMACBC), potential PET ligands for tumor detection.
J Med Chem
; 45(11): 2250-9, 2002 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-12014963