Detalhe da pesquisa
1.
Direct activation of a bacterial innate immune system by a viral capsid protein.
Nature
; 612(7938): 132-140, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36385533
2.
Linking function to global and local dynamics in an elevator-type transporter.
Proc Natl Acad Sci U S A
; 118(49)2021 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34873050
3.
A topological switch in CFTR modulates channel activity and sensitivity to unfolding.
Nat Chem Biol
; 17(9): 989-997, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34341587
4.
Assessing the Role of Lipids in the Molecular Mechanism of Membrane Proteins.
Int J Mol Sci
; 22(14)2021 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298884
5.
Deuteros: software for rapid analysis and visualization of data from differential hydrogen deuterium exchange-mass spectrometry.
Bioinformatics
; 35(17): 3171-3173, 2019 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30649183
6.
Interrogating Membrane Protein Conformational Dynamics within Native Lipid Compositions.
Angew Chem Int Ed Engl
; 56(49): 15654-15657, 2017 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29049865
7.
Protonation drives the conformational switch in the multidrug transporter LmrP.
Nat Chem Biol
; 10(2): 149-55, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316739
8.
Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems.
Cell Host Microbe
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38821063
9.
Hydrogen-deuterium exchange coupled to mass spectrometry: A multifaceted tool to decipher the molecular mechanism of transporters.
Biochimie
; 205: 95-101, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36037883
10.
A polyamine acetyltransferase regulates the motility and biofilm formation of Acinetobacter baumannii.
Nat Commun
; 14(1): 3531, 2023 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37316480
11.
The structure of DarB in complex with RelNTD reveals nonribosomal activation of Rel stringent factors.
Sci Adv
; 9(3): eade4077, 2023 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36652515
12.
Membrane Protein Production in Lactococcus lactis for Structural Studies.
Methods Mol Biol
; 2127: 29-45, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32112313
13.
A glimpse into the molecular mechanism of integral membrane proteins through hydrogen-deuterium exchange mass spectrometry.
Protein Sci
; 29(6): 1285-1301, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32170968
14.
An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity.
Nat Struct Mol Biol
; 27(9): 829-835, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32719456
15.
Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter.
Nat Commun
; 11(1): 6162, 2020 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33268777
16.
Integrating hydrogen-deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins.
Nat Protoc
; 14(11): 3183-3204, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31605097
17.
Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun
; 10(1): 3814, 2019 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31444342
18.
Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry.
J Vis Exp
; (140)2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30371663
19.
Direct protein-lipid interactions shape the conformational landscape of secondary transporters.
Nat Commun
; 9(1): 4151, 2018 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30297844
20.
Lipids modulate the conformational dynamics of a secondary multidrug transporter.
Nat Struct Mol Biol
; 23(8): 744-51, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27399258