Detalhe da pesquisa
1.
Acetate is a bioenergetic substrate for human glioblastoma and brain metastases.
Cell
; 159(7): 1603-14, 2014 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25525878
2.
ASCL1 regulates neurodevelopmental transcription factors and cell cycle genes in brain tumors of glioma mouse models.
Glia
; 68(12): 2613-2630, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32573857
3.
In vivo MRS measurement of 2-hydroxyglutarate in patient-derived IDH-mutant xenograft mouse models versus glioma patients.
Magn Reson Med
; 84(3): 1152-1160, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32003035
4.
In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma.
Proc Natl Acad Sci U S A
; 111(12): 4542-7, 2014 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24616497
5.
¹H MRS characterization of neurochemical profiles in orthotopic mouse models of human brain tumors.
NMR Biomed
; 28(1): 108-15, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25394324
6.
Conditions for (13)C NMR detection of 2-hydroxyglutarate in tissue extracts from isocitrate dehydrogenase-mutated gliomas.
Anal Biochem
; 481: 4-6, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25908561
7.
Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression.
Nat Med
; 12(8): 933-8, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16862154
8.
Metabolism of [U-13 C]glucose in human brain tumors in vivo.
NMR Biomed
; 25(11): 1234-44, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22419606
9.
Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.
NMR Biomed
; 25(10): 1177-86, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22383401
10.
Synaptotagmin-1, -2, and -9: Ca(2+) sensors for fast release that specify distinct presynaptic properties in subsets of neurons.
Neuron
; 54(4): 567-81, 2007 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-17521570
11.
Gliomas Interact with Non-glioma Brain Cells via Extracellular Vesicles.
Cell Rep
; 30(8): 2489-2500.e5, 2020 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32101730
12.
IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma.
Nat Cell Biol
; 21(8): 1003-1014, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371825
13.
N-glycosylation is essential for vesicular targeting of synaptotagmin 1.
Neuron
; 41(1): 85-99, 2004 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-14715137
14.
Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo.
Cell Metab
; 28(5): 793-800.e2, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30146487
15.
Measurement of 13 C turnover into glutamate and glutamine pools in brain tumor patients.
FEBS Lett
; 591(21): 3548-3554, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28963851
16.
Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma.
Cell Rep
; 18(4): 961-976, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28122245
17.
Hepatic gluconeogenesis influences (13)C enrichment in lactate in human brain tumors during metabolism of [1,2-(13)C]acetate.
Neurochem Int
; 97: 133-6, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27020407
18.
Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma.
J Clin Oncol
; 34(33): 4030-4039, 2016 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28248126
19.
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas.
Nat Med
; 18(4): 624-9, 2012 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22281806
20.
Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.
Cell Metab
; 15(6): 827-37, 2012 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22682223