Detalhe da pesquisa
1.
Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function.
Proc Natl Acad Sci U S A
; 121(12): e2310866121, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38483996
2.
Photosynthetic reaction center variants made via genetic code expansion show Tyr at M210 tunes the initial electron transfer mechanism.
Proc Natl Acad Sci U S A
; 118(51)2021 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34907018
3.
Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase.
Biochemistry
; 62(11): 1589-1593, 2023 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37184546
4.
Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants.
J Biol Chem
; 298(3): 101610, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35065072
5.
Structure-Based Prototyping of Allosteric Inhibitors of Human Uridine/Cytidine Kinase 2 (UCK2).
Biochemistry
; 61(21): 2261-2266, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36190114
6.
Energetic Basis and Design of Enzyme Function Demonstrated Using GFP, an Excited-State Enzyme.
J Am Chem Soc
; 144(9): 3968-3978, 2022 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35200017
7.
Protein Electric Fields Enable Faster and Longer-Lasting Covalent Inhibition of ß-Lactamases.
J Am Chem Soc
; 144(45): 20947-20954, 2022 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36324090
8.
Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction.
J Am Chem Soc
; 142(35): 14933-14939, 2020 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32786753
9.
Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins.
J Am Chem Soc
; 141(38): 15250-15265, 2019 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31450887
10.
Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase.
Biochemistry
; 57(43): 6201-6208, 2018 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30289692
11.
Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module.
J Am Chem Soc
; 140(21): 6518-6521, 2018 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29762030
12.
Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis.
Nature
; 483(7389): 355-8, 2012 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22388816
13.
The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.
Biochemistry
; 56(36): 4751-4756, 2017 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28832129
14.
Cell fate regulation governed by a repurposed bacterial histidine kinase.
PLoS Biol
; 12(10): e1001979, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25349992
15.
Use of transmission electron microscopy to identify nanocrystals of challenging protein targets.
Proc Natl Acad Sci U S A
; 111(23): 8470-5, 2014 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24872454
16.
Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Proc Natl Acad Sci U S A
; 111(48): 17122-7, 2014 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25362050
17.
An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.
Nat Chem Biol
; 10(11): 977-83, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25242553
18.
X-ray absorption spectroscopic investigation of the electronic structure differences in solution and crystalline oxyhemoglobin.
Proc Natl Acad Sci U S A
; 110(41): 16333-8, 2013 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24062465
19.
An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene.
Nature
; 458(7240): 919-23, 2009 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19370033
20.
Folate binding site of flavin-dependent thymidylate synthase.
Proc Natl Acad Sci U S A
; 109(39): 15722-7, 2012 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23019356