Detalhe da pesquisa
1.
Morphological, behavioral and cellular analyses revealed different phenotypes in Wolfram syndrome wfs1a and wfs1b zebrafish mutant lines.
Hum Mol Genet
; 31(16): 2711-2727, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35325133
2.
Microglial P2X4 receptors promote ApoE degradation and contribute to memory deficits in Alzheimer's disease.
Cell Mol Life Sci
; 80(5): 138, 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37145189
3.
Convolamine, a tropane alkaloid extracted from Convolvulus plauricalis, is a potent sigma-1 receptor-positive modulator with cognitive and neuroprotective properties.
Phytother Res
; 38(2): 694-712, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38011416
4.
Targeting N-Methyl-d-Aspartate Receptors in Neurodegenerative Diseases.
Int J Mol Sci
; 25(7)2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38612544
5.
Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss.
Hum Mol Genet
; 30(19): 1785-1796, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34059922
6.
The Intriguing Sigma-1 and Sigma-2 Receptors and Their Potential Therapeutic Roles 2.0.
Int J Mol Sci
; 24(21)2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37958850
7.
Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer's Disease Mouse Model upon Irradiation.
J Am Chem Soc
; 144(7): 3279-3284, 2022 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35138833
8.
Sigma-1 receptor is a key genetic modulator in amyotrophic lateral sclerosis.
Hum Mol Genet
; 29(4): 529-540, 2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31696229
9.
Synthesis and Biological Evaluation of Flavonoid-Cinnamic Acid Amide Hybrids with Distinct Activity against Neurodegeneration in Vitro and in Vivo.
Chemistry
; 28(39): e202200786, 2022 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35621167
10.
Restoring glutamate receptosome dynamics at synapses rescues autism-like deficits in Shank3-deficient mice.
Mol Psychiatry
; 26(12): 7596-7609, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34331007
11.
Fenfluramine modulates the anti-amnesic effects induced by sigma-1 receptor agonists and neuro(active)steroids in vivo.
Epilepsy Behav
; 127: 108526, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007961
12.
Defective tubulin detyrosination causes structural brain abnormalities with cognitive deficiency in humans and mice.
Hum Mol Genet
; 28(20): 3391-3405, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31363758
13.
Anti-Amnesic and Neuroprotective Effects of Fluoroethylnormemantine in a Pharmacological Mouse Model of Alzheimer's Disease.
Int J Neuropsychopharmacol
; 24(2): 142-157, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32977336
14.
Analysis of CX3CR1 haplodeficiency in male and female APPswe/PSEN1dE9 mice along Alzheimer disease progression.
Brain Behav Immun
; 91: 404-417, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33190798
15.
Amyloid Beta Peptide Is an Endogenous Negative Allosteric Modulator of Leptin Receptor.
Neuroendocrinology
; 111(4): 370-387, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-32335558
16.
Zebrafish Models to Study New Pathways in Tauopathies.
Int J Mol Sci
; 22(9)2021 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33924882
17.
Use of Zebrafish Models to Boost Research in Rare Genetic Diseases.
Int J Mol Sci
; 22(24)2021 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34948153
18.
Sigma-1 Receptor Is Critical for Mitochondrial Activity and Unfolded Protein Response in Larval Zebrafish.
Int J Mol Sci
; 22(20)2021 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681705
19.
Improvement of BDNF signalling by P42 peptide in Huntington's disease.
Hum Mol Genet
; 27(17): 3012-3028, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29860423
20.
Sterubin: Enantioresolution and Configurational Stability, Enantiomeric Purity in Nature, and Neuroprotective Activity in Vitro and in Vivo.
Chemistry
; 26(32): 7299-7308, 2020 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32358806