Detalhe da pesquisa
1.
Somatic Evolution in Non-neoplastic IBD-Affected Colon.
Cell
; 182(3): 672-684.e11, 2020 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32697969
2.
CIAO1 and MMS19 deficiency: A lethal neurodegenerative phenotype caused by cytosolic Fe-S cluster protein assembly disorders.
Genet Med
; 26(6): 101104, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38411040
3.
Reduced nicotinamide mononucleotide is a new and potent NAD+ precursor in mammalian cells and mice.
FASEB J
; 35(4): e21456, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33724555
4.
A community-based trial of a psychosocial eHealth intervention for parents of children with cancer.
Pediatr Blood Cancer
; 69(1): e29352, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34532970
5.
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion.
PLoS Genet
; 15(3): e1007633, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30845140
6.
Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research.
Gut
; 73(2): 379-383, 2024 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754608
7.
Cutting through dogma: a novel tool to dissect lactate biology.
J Physiol
; 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38739005
8.
Mouse genomic variation and its effect on phenotypes and gene regulation.
Nature
; 477(7364): 289-94, 2011 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21921910
9.
Mouse models of colorectal cancer as preclinical models.
Bioessays
; 37(8): 909-20, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26115037
10.
Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.
EMBO J
; 31(11): 2486-97, 2012 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22510880
11.
Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.
PLoS Genet
; 8(11): e1003022, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23166506
12.
Akt and mTORC1 have different roles during liver tumorigenesis in mice.
Gastroenterology
; 144(5): 1055-65, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23376645
13.
The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation.
Blood
; 119(6): 1370-9, 2012 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-22184403
14.
The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function - Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation.
Biochim Biophys Acta Mol Basis Dis
; 1870(2): 166978, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38061598
15.
Low-dose naltrexone extends healthspan and lifespan in C. elegans via SKN-1 activation.
iScience
; 27(6): 109949, 2024 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38799567
16.
Defining predictors of responsiveness to advanced therapies in Crohn's disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine.
BMJ Open
; 14(4): e073639, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38631839
17.
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.
Proc Natl Acad Sci U S A
; 107(34): 15145-50, 2010 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20696900
18.
Repurposing nucleoside reverse transcriptase inhibitors (NRTIs) to slow aging.
Ageing Res Rev
; 92: 102132, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37984625
19.
Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4.
Cell Rep
; 42(1): 111928, 2023 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36640360
20.
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models.
Nat Commun
; 14(1): 2779, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188705