Detalhe da pesquisa
1.
Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors.
Bioorg Med Chem Lett
; 22(13): 4377-85, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22632936
2.
Triterpene based compounds with potent anti-maturation activity against HIV-1.
Bioorg Med Chem Lett
; 18(24): 6377-80, 2008 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18996008
3.
Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets.
Protein Sci
; 24(4): 446-63, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25287718
4.
Discovery of (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor.
J Med Chem
; 55(17): 7480-501, 2012 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22913511
5.
Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1.
Mol Cancer Ther
; 10(12): 2267-75, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21980130
6.
Chemical proteomics identifies Nampt as the target of CB30865, an orphan cytotoxic compound.
Chem Biol
; 17(6): 659-64, 2010 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20609415
7.
Analogues of 4-[(7-Bromo-2-methyl-4-oxo-3H-quinazolin-6-yl)methylprop-2-ynylamino]-N-(3-pyridylmethyl)benzamide (CB-30865) as potent inhibitors of nicotinamide phosphoribosyltransferase (Nampt).
J Med Chem
; 53(24): 8734-46, 2010 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21080724
8.
The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding.
J Biol Chem
; 279(34): 36059-71, 2004 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15218037