Detalhe da pesquisa
1.
Nucleic Acid Sensors as Therapeutic Targets for Human Disease.
Immunity
; 53(1): 78-97, 2020 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32668230
2.
Activation of human STING by a molecular glue-like compound.
Nat Chem Biol
; 20(3): 365-372, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37828400
3.
Author Correction: SLC19A1 transports immunoreactive cyclic dinucleotides.
Nature
; 579(7800): E12, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144410
4.
SLC19A1 transports immunoreactive cyclic dinucleotides.
Nature
; 573(7774): 434-438, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511694
5.
Synergy of a STING agonist and an IL-2 superkine in cancer immunotherapy against MHC I-deficient and MHC I+ tumors.
Proc Natl Acad Sci U S A
; 119(22): e2200568119, 2022 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35588144
6.
Mucosal Vaccination with Cyclic Dinucleotide Adjuvants Induces Effective T Cell Homing and IL-17-Dependent Protection against Mycobacterium tuberculosis Infection.
J Immunol
; 208(2): 407-419, 2022 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34965963
7.
Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA.
J Immunol
; 196(7): 3191-8, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26927800
8.
Comment on "The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele".
J Immunol
; 198(11): 4183-4185, 2017 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28533276
9.
Modulation of Kinase Activities In Vitro by Hepatitis C Virus Protease NS3/NS4A Mediated-Cleavage of Key Immune Modulator Kinases.
Cells
; 12(3)2023 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36766748
10.
Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study.
Clin Cancer Res
; 29(1): 110-121, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36282874
11.
Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas.
Clin Cancer Res
; 28(4): 677-688, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34716197
12.
Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila.
PLoS Pathog
; 5(11): e1000665, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19936053
13.
Induction of type I interferons by bacteria.
Cell Microbiol
; 12(7): 881-90, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20482555
14.
NK cells mediate clearance of CD8+ T cell-resistant tumors in response to STING agonists.
Sci Immunol
; 5(45)2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32198222
15.
Combining STING-based neoantigen-targeted vaccine with checkpoint modulators enhances antitumor immunity in murine pancreatic cancer.
JCI Insight
; 3(20)2018 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333318
16.
STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection.
Cell Rep
; 23(5): 1435-1447, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29719256
17.
TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors.
Cancer Immunol Res
; 6(4): 422-433, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29472271
18.
Correction: Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas.
Clin Cancer Res
; 29(12): 2336, 2023 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37309603
19.
Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity.
Cell Rep
; 25(11): 3074-3085.e5, 2018 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30540940
20.
The host STING pathway at the interface of cancer and immunity.
J Clin Invest
; 126(7): 2404-11, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27367184