Detalhe da pesquisa
1.
Conformational fingerprinting with Raman spectroscopy reveals protein structure as a translational biomarker of muscle pathology.
Analyst
; 149(9): 2738-2746, 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38533726
2.
Combining electromyography and Raman spectroscopy: optical EMG.
Muscle Nerve
; 68(4): 464-470, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37477391
3.
Assessment of the Precision in Measuring Glutathione at 3 T With a MEGA-PRESS Sequence in Primary Motor Cortex and Occipital Cortex.
J Magn Reson Imaging
; 55(2): 435-442, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34322948
4.
Fiber optic Raman spectroscopy for the evaluation of disease state in Duchenne muscular dystrophy: An assessment using the mdx model and human muscle.
Muscle Nerve
; 66(3): 362-369, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35762576
5.
Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation.
Nat Rev Drug Discov
; 22(3): 185-212, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543887
6.
Janus kinase inhibitors are potential therapeutics for amyotrophic lateral sclerosis.
Transl Neurodegener
; 12(1): 47, 2023 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37828541
7.
Non-negative matrix factorisation of Raman spectra finds common patterns relating to neuromuscular disease across differing equipment configurations, preclinical models and human tissue.
J Raman Spectrosc
; 54(3): 258-268, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38505661
8.
Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP.
Brain Pathol
; 33(1): e13104, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35871544
9.
A Y374X TDP43 truncation leads to an altered metabolic profile in amyotrophic lateral sclerosis fibroblasts driven by pyruvate and TCA cycle intermediate alterations.
Front Aging Neurosci
; 15: 1151848, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37251807
10.
A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins.
Sci Transl Med
; 15(685): eabo3823, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36857431
11.
Caudal-Rostral Progression of Alpha Motoneuron Degeneration in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis.
Antioxidants (Basel)
; 11(5)2022 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35624847
12.
Extensive phenotypic characterisation of a human TDP-43Q331K transgenic mouse model of amyotrophic lateral sclerosis (ALS).
Sci Rep
; 11(1): 16659, 2021 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34404845
13.
Proteomic Approaches to Study Cysteine Oxidation: Applications in Neurodegenerative Diseases.
Front Mol Neurosci
; 14: 678837, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34177463
14.
The GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1G93A and TDP-43Q331K transgenic mouse models of ALS.
Sci Rep
; 11(1): 17027, 2021 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426623
15.
Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS.
Mol Ther Methods Clin Dev
; 21: 413-433, 2021 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33869658
16.
In Vivo Fiber Optic Raman Spectroscopy of Muscle in Preclinical Models of Amyotrophic Lateral Sclerosis and Duchenne Muscular Dystrophy.
ACS Chem Neurosci
; 12(10): 1768-1776, 2021 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33950665
17.
Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin.
Biomolecules
; 11(10)2021 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34680132
18.
Guidelines for preclinical animal research in ALS/MND: A consensus meeting.
Amyotroph Lateral Scler
; 11(1-2): 38-45, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20184514
19.
Female sex mitigates motor and behavioural phenotypes in TDP-43Q331K knock-in mice.
Sci Rep
; 10(1): 19220, 2020 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33154447
20.
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases.
Nat Rev Neurol
; 16(8): 440-456, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669685