Detalhe da pesquisa
1.
Pharmacological targeting of netrin-1 inhibits EMT in cancer.
Nature
; 620(7973): 402-408, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37532929
2.
Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer.
Nature
; 620(7973): 409-416, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37532934
3.
The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving as a Dependence Receptor.
Mol Cell
; 72(3): 413-425.e5, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30293784
4.
Netrin-1 and its receptor DCC modulate survival and death of dopamine neurons and Parkinson's disease features.
EMBO J
; 40(3): e105537, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33351190
5.
Metastatic Infiltration of Nervous Tissue and Periosteal Nerve Sprouting in Multiple Myeloma-Induced Bone Pain in Mice and Human.
J Neurosci
; 43(29): 5414-5430, 2023 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37286351
6.
Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity.
Proc Natl Acad Sci U S A
; 118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34470826
7.
Hepatic inflammation elicits production of proinflammatory netrin-1 through exclusive activation of translation.
Hepatology
; 76(5): 1345-1359, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35253915
8.
Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.
Nature
; 545(7654): 350-354, 2017 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28445456
9.
Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1.
Development
; 145(2)2018 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29343638
10.
Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth.
PLoS Biol
; 16(5): e2002912, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29750782
11.
The dependence receptor TrkC triggers mitochondria-dependent apoptosis upon Cobra-1 recruitment.
Mol Cell
; 51(5): 632-46, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24034695
12.
p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis.
PLoS Genet
; 13(9): e1007024, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28945745
13.
The dependence receptor TrkC regulates the number of sensory neurons during DRG development.
Dev Biol
; 442(2): 249-261, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30071216
14.
Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus.
PLoS Biol
; 14(3): e1002421, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27031829
15.
Hepatocellular carcinoma-associated depletion of the netrin-1 receptor Uncoordinated Phenotype-5A (UNC5A) skews the hepatic unfolded protein response towards prosurvival outcomes.
Biochem Biophys Res Commun
; 495(4): 2425-2431, 2018 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29277614
16.
The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase.
Mol Cell
; 40(6): 863-76, 2010 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21172653
17.
Molecular characterization of Netrin-1 and APP receptor binding: New leads to block the progression of senile plaques in Alzheimer's disease.
Biochem Biophys Res Commun
; 488(3): 466-470, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28501620
18.
Netrin-4 regulates stiffness and metastasis.
Nat Mater
; 20(6): 722-723, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34045700
19.
DCC constrains tumour progression via its dependence receptor activity.
Nature
; 482(7386): 534-7, 2011 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22158121
20.
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells.
Nucleic Acids Res
; 43(12): 5838-54, 2015 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26007656