Detalhe da pesquisa
1.
Intracellular calcium leak as a therapeutic target for RYR1-related myopathies.
Acta Neuropathol
; 139(6): 1089-1104, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32236737
2.
The Activation of Protein Kinase A by the Calcium-Binding Protein S100A1 Is Independent of Cyclic AMP.
Biochemistry
; 56(17): 2328-2337, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28409622
3.
Investigating gating mechanisms of ion channels using temperature-resolved cryoEM.
Microsc Microanal
; 27(Suppl 1): 1690-1694, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37644957
4.
High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor.
Structure
; 30(1): 172-180.e3, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34469755
5.
A drug and ATP binding site in type 1 ryanodine receptor.
Structure
; 30(7): 1025-1034.e4, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35580609
6.
Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv
; 8(29): eabo1272, 2022 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35857850
7.
RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation.
Acta Neuropathol Commun
; 9(1): 186, 2021 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34809703
8.
Intracellular calcium leak in heart failure and atrial fibrillation: a unifying mechanism and therapeutic target.
Nat Rev Cardiol
; 17(11): 732-747, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32555383
9.
Ssd1 and the cell wall integrity pathway promote entry, maintenance, and recovery from quiescence in budding yeast.
Mol Biol Cell
; 30(17): 2205-2217, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31141453
10.
Loss of S100A1 expression leads to Ca2+ release potentiation in mutant mice with disrupted CaM and S100A1 binding to CaMBD2 of RyR1.
Physiol Rep
; 6(15): e13822, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30101473
11.
X-ray crystal structure of human calcium-bound S100A1.
Acta Crystallogr F Struct Biol Commun
; 73(Pt 4): 215-221, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28368280
12.
Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif.
Acta Crystallogr F Struct Biol Commun
; 73(Pt 4): 209-214, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28368279
13.
Novel protein-inhibitor interactions in site 3 of Ca(2+)-bound S100B as discovered by X-ray crystallography.
Acta Crystallogr D Struct Biol
; 72(Pt 6): 753-60, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27303795
14.
Reply to 'Mechanisms of ryanodine receptor 2 dysfunction in heart failure'.
Nat Rev Cardiol
; 17(11): 749-750, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32901149
15.
Key events during the transition from rapid growth to quiescence in budding yeast require posttranscriptional regulators.
Mol Biol Cell
; 24(23): 3697-709, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24088570