Detalhe da pesquisa
1.
Development of BET inhibitors as potential treatments for cancer: A search for structural diversity.
Bioorg Med Chem Lett
; 44: 128108, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33991625
2.
BMS-871: a novel orally active pan-Notch inhibitor as an anticancer agent.
Bioorg Med Chem Lett
; 25(9): 1905-9, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25857941
3.
Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors.
Bioorg Med Chem
; 20(6): 1961-72, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22137930
4.
Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties.
ACS Med Chem Lett
; 13(7): 1165-1171, 2022 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35859878
5.
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.
J Med Chem
; 64(19): 14247-14265, 2021 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34543572
6.
Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors: SAR of a series of 3-[6-(4-substituted-piperazin-1-yl)-4-methyl-1H-benzimidazol-2-yl]-1H-pyridine-2-one.
Bioorg Med Chem Lett
; 20(10): 3182-5, 2010 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20399649
7.
Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy.
Sci Adv
; 5(2): eaav2437, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30801016
8.
Tissue distribution and tumor uptake of folate receptor-targeted epothilone folate conjugate, BMS-753493, in CD2F1 mice after systemic administration.
Acta Pharm Sin B
; 6(5): 460-467, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27709015
9.
Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors.
ACS Med Chem Lett
; 6(5): 523-7, 2015 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26005526
10.
Preclinical efficacy spectrum and pharmacokinetics of ixabepilone.
Cancer Chemother Pharmacol
; 63(2): 201-12, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18350296
11.
BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR.
Mol Cancer Ther
; 8(12): 3341-9, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19996272
12.
Discovery of a 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitor (BMS-754807) of insulin-like growth factor receptor (IGF-1R) kinase in clinical development.
J Med Chem
; 52(23): 7360-3, 2009 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19778024