Detalhe da pesquisa
1.
Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction.
Mol Ther
; 28(7): 1684-1695, 2020 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32402246
2.
Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets.
Mol Ther
; 27(4): 866-877, 2019 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30902585
3.
Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells.
Blood
; 125(17): 2597-604, 2015 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733580
4.
Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.
Mol Ther
; 23(8): 1380-1390, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25939491
5.
Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures.
Nat Methods
; 8(1): 74-9, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21131970
6.
Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency.
Hepatol Commun
; 7(3): e0070, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36848094
7.
Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma.
Neuro Oncol
; 24(8): 1318-1330, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35100373
8.
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.
Nat Med
; 25(7): 1131-1142, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31263285
9.
Delivery of Genome Editing Reagents to Hematopoietic Stem/Progenitor Cells.
Curr Protoc Stem Cell Biol
; 36: 5B.4.1-5B.4.10, 2016 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26840227
10.
Isogenic human cell lines for drug discovery: regulation of target gene expression by engineered zinc-finger protein transcription factors.
J Biomol Screen
; 10(4): 304-13, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15964931
11.
Pharmacological analysis of CCK2 receptors up-regulated using engineered transcription factors.
Regul Pept
; 129(1-3): 227-32, 2005 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15927720
12.
Cell lines for drug discovery: elevating target-protein levels using engineered transcription factors.
J Biomol Screen
; 9(1): 44-51, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15006148