Detalhe da pesquisa
1.
Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T-cell lymphoma.
Blood
; 140(23): 2463-2476, 2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35960849
2.
TAL1 cooperates with PI3K/AKT pathway activation in T-cell acute lymphoblastic leukemia.
Haematologica
; 107(10): 2304-2317, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35354248
3.
Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.
Blood
; 134(16): 1323-1336, 2019 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31492675
4.
Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene.
Haematologica
; 102(9): 1605-1616, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28659337
5.
JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.
Blood
; 124(20): 3092-100, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193870
6.
Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia.
PLoS Genet
; 9(12): e1003997, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24367274
7.
Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.
Nat Genet
; 39(5): 593-5, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17435759
8.
NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins.
Haematologica
; 99(1): 85-93, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23872305
9.
PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia.
Blood
; 117(26): 7090-8, 2011 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21551237
10.
MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context.
Haematologica
; 96(5): 779-83, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21193420
11.
Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified.
Nat Commun
; 12(1): 3705, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140493
12.
The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia.
Clin Cancer Res
; 26(21): 5747-5758, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32826328
13.
In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.
Haematologica
; 93(4): 533-42, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18322257
14.
Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion.
Haematologica
; 93(1): 49-56, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18166785
15.
EML1-ABL1 Is Activated by Coiled-Coil-Mediated Oligomerization and Induces T-Cell Acute Lymphoblastic Leukemia or Myeloproliferative Disease in a Mouse Bone Marrow Transplant Model.
Hemasphere
; 2(2): e32, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-31723760
16.
Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.
Cancer Cell
; 34(2): 271-285.e7, 2018 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30107177
17.
The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitors.
Haematologica
; 92(1): 27-34, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17229632
18.
Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate.
Clin Cancer Res
; 12(8): 2622-7, 2006 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16638875
19.
Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia.
Cancer Res
; 64(18): 6385-9, 2004 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15374944
20.
Oncogenic Cooperation Between IL7R-JAK-STAT Pathway Mutations.
Hemasphere
; 5(9): e637, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34476346