Psychosocial development measures modification for adolescents with intellectual and developmental disabilities.

BACKGROUND: Although diagnosis and identification of IDD is improving, adolescents with IDD receive limited attention in research, particularly concerning their psychosocial development. Measures developed and normed with typically developing populations may not be appropriate for IDD populations and may result in biased assessment. AIM: This study aimed to develop and validate modified psychosocial development assessments for adolescents with intellectual and developmental disabilities (IDD), addressing the absence of such assessments. METHOD: It involved two phases: modifying existing instruments and validating the revised versions. Four stakeholder groups participated: adolescents with IDD, parents, and scholars in adolescent developmental and disabilities. Validation included two groups: neurotypical adolescents completing both measures and IDD adolescents completing modified measures. RESULTS: Confirmatory factor analyses identified the need to adjust or eliminate scales for better understanding by individuals with IDD. The modified instruments provided suitable measures for assessing psychosocial development in adolescents with IDD. DISCUSSION: All the scales allowed for accommodation toward comprehension for those with IDD except for identity formation. Further work is needed to understand the challenges associated with assessing identity formation in adolescents with IDD. The active involvement of and participation from adolescents with IDD and their parents in this research was paramount to understanding their comprehension and needs. CONCLUSION: This study highlights the importance of tailored assessments for accurate measurement of IDD individuals' development, benefiting the assessment of all adolescents.

A Lack of GD3 Synthase Leads to Impaired Renal Expression of Connexins and Pannexin1 in St8sia1 Knockout Mice.

The aim of this study was to determine the effects of altered ganglioside composition on the expression of Cx37, Cx40, Cx43, Cx45, and Panx1 in different kidney regions of St8sia1 gene knockout mice (St8sia1 KO) lacking the GD3 synthase enzyme. Experiments were performed in twelve male 6-month-old mice: four wild-type (C57BL/6-type, WT) and eight St8sia1 KO mice. After euthanasia, kidney tissue was harvested, embedded in paraffin wax, and processed for immunohistochemistry. The expression of connexins and Panx1 was determined in different regions of the kidney: cortex (CTX.), outer stripe of outer medulla (O.S.), inner stripe of outer medulla (IN.S.), and inner medulla (IN.MED.). We determined significantly lower expression of Cx37, Cx40, Cx45, and Panx1 in different parts of the kidneys of St8sia1 KO mice compared with WT. The most consistent decrease was found in the O.S. where all markers (Cx 37, 40, 45 and Panx1) were disrupted in St8si1 KO mice. In the CTX. region, we observed decrease in the expression of Cx37, Cx45, and Panx1, while reduced expression of Cx37 and Panx1 was more specific to IN.S. The results of the present study suggest that deficiency of GD3 synthase in St8sia1 KO mice leads to disruption of renal Cx expression, which is probably related to alteration of ganglioside composition.

How Adolescents Use Text Messaging Through their High School Years.

Co-construction theory suggests adolescents use digital communication to address developmental challenges. For a sample of 214 ethnically diverse adolescents, this research used direct observation to investigate the frequency, content, and timing of texting with parents, peers, and romantic partners through grades 9-12. Analyses showed that texting frequency follows a curvilinear trajectory, peaking in eleventh grade. Adolescents discussed a range of topics, predominantly with peers. Communication with parents was less frequent, but consistent over time. Approximately 45-65% of adolescents communicated with romantic partners, texting heavily and about topics similar to those discussed with peers. Texting may help adolescents navigate key developmental challenges of adolescence-the establishment of autonomy, intimate peer relationships, romantic relationships, and self-identity.

Adolescents' externalizing behaviors and antisocial text messaging across the broader peer network: Implications for socialization and selection effects.

Adolescents' peer networks provide an important context that can contribute to increases in antisocial behavior. By a process called deviancy training, peers can both model and reinforce these behaviors, thereby conveying group norms about the acceptability of such behaviors. This research examined the relationship between the proportion of adolescents' peers who exchanged antisocial text messages and externalizing behaviors during high school. In Study 1, parent-, teacher-, and self-reports of rule-breaking and aggression were collected for a sample of adolescents (n = 167, 80 girls; 22.2% Black, 51.5% Caucasian, 18.7% Hispanic) during the summers before and after 9th grade. Total text frequency, frequency of antisocial texts, and the proportion of the peer network who exchanged antisocial messages were examined as predictors of antisocial behavior. The proportion of peers who exchanged antisocial texts significantly predicted rule-breaking, but not aggression. Study 2 examined the direction of the relationship documented in Study 1 more thoroughly. Externalizing behaviors at 9th, 10th, and 11th grade were evaluated as predictors of the proportion of the peer network that exchanged texts about antisocial topics (n = 205, 98 girls; 22.4% Black, 53.7% Caucasian, 16.9% Hispanic). Externalizing behaviors predicted the proportion of adolescents' peer network that exchanged antisocial texts in each of the subsequent years, but this proportion of the peer network exchanging antisocial communication did not predict subsequent externalizing behaviors. The findings suggest that the extent to which antisocial communication permeates the peer group is a selection effect.

Older Adolescents' Understanding of Participant Rights in the BlackBerry Project, a Longitudinal Ambulatory Assessment Study.

For a long-term, longitudinal study that used BlackBerry smartphones for passive ambulatory assessment among older adolescents, this study focused on three areas of ethical concern: (1) adolescents' competence to give assent; (2) understanding of confidentiality, the protection of information, and project goals; and (3) awareness of procedures and benefits, and comfort with the research design. One hundred and seventy-eight participants were 17 and 18 years old (84 girls). Results suggested that participants freely gave consent and understood most, but not all of the informed consent information. Participants reported a high level of satisfaction. Participants showed less understanding of when their confidentiality would be broken and how data would be protected.

Brief report: Identifying defenders of peer victimization.

Betweenness centrality quantifies the amount of network flow that a network member controls as hypothetical traffic passes between network members. Those with high betweenness centrality within the peer social network based on nominations of liking may be especially important connectors between individuals who do not like each other. This study tested the hypothesis that individuals' betweenness centrality would predict their defending of victimized peers. After controlling for popularity, perception of being liked, and defenders' victimization, betweenness centrality predicted defending. Those found to be connectors within the peer group were more likely to be those who defend peer victims. This investigation showed that analysis of betweenness centrality is a viable way to identify potential defenders in research and also those who could potentially act as mediators.

Perceptions of intimacy and friendship reciprocity moderate peer influence on aggression.

Previous research has shown that close friends' influence can exacerbate adolescents' aggressive behavior, but results of studies which examine whether friendships of greater or lesser qualities moderate peer influence effects are inconsistent. The present study tested whether the perception of the positive friendship quality of intimate exchange and friendship reciprocity moderated best friend influence on participant aggression over time. The 243 participants were approximately 12 years old and ethnically diverse. Neither intimate exchange nor reciprocity significantly moderated friend influence on aggression in a simple way, but the interaction of intimate exchange and friendship reciprocity predicted peer influence on participants' aggression over time. Specifically, highly intimate, nonreciprocal best friendships and less intimate, reciprocal best friendships showed greatest influence when friends' proportion of peer nominations for aggression was high. Reciprocity and intimacy should be considered when predicting peer influence on aggression.

Left Atrial Myxoma and Antiphospholipid Syndrome-A Case Report.

Cardiac myxoma (CM) is the most frequent type of primary cardiac neoplasm and is responsible for 58 to 80% of primary cardiac tumors. The antiphospholipid syndrome (APS) occurs most commonly in the systemic lupus erythematosus but it can be also found in other conditions. The coexistence of CM and APS is rarely described in the literature. We report an unusual case of the left atrial myxoma and concomitant APS in a female patient who presented with right-sided hemiplegia. Although rare, we must think about the CM in patients with a newly diagnosed APS and left atrial mass. Nevertheless, we must make a distinction from other possible cardiac structures, especially atrial thrombus. Transthoracic echocardiography is the most frequently used initial imaging modality to detect CM. The aim of this case report was to emphasize that additional imaging modalities and multidisciplinary approach are mandatory in making a proper diagnosis and to choose a further treatment strategy.

Prospective associations between peer support, academic competence, and anxiety in college students.

Previous literature has demonstrated that peer support is instrumental for the promotion of adaptive academic and mental health outcomes; however, limited research has examined prospective directional associations between peer support and adjustment within college settings. The purpose of this study was to investigate the longitudinal associations between peer support, academic competence, and anxiety among U.S. college students. U.S. students from a diverse 4-year university (N = 251, 75% women, 24% men, and < 1% a different gender) reported on peer support, academic competence, and anxiety using validated questionnaires at two time points (Fall term of sophomore year and Spring term of senior year). Results showed that peer support was positively associated with academic competence over time but was not significantly related to future anxiety. Academic competence did not significantly predict peer support or anxiety over time, but anxiety was associated with lower future academic competence. These findings offer insight into how types of social relationships link with academic motivation and anxiety over time within educational settings.

The Association of Military Sexual Harassment/Assault With Suicide Ideation, Plans, Attempts, and Mortality Among US Service Members/Veterans: A Meta-Analysis.

Suicide rates continue to increase among service members/veterans. Military sexual harassment/assault (MSH/A) may increase risk of suicide, but little is known about the collective magnitude of associations between MSH/A and suicide outcomes, including ideation, plan, attempt, and mortality. The current meta-analysis addressed this literature gap while testing potential moderators of gender, marital status, discharge status, and military branch. PsycINFO, PubMed, Dissertations/Theses, relevant citation lists, and conference brochures were reviewed for papers that included quantitative analyses in English, U.S. military samples, and measures of MSH/A and suicide ideation/plan/attempt/mortality. The search resulted in 22 studies (N = 10,898,875) measuring the association of MSH/A with suicide ideation (k = 15), plans (k = 1), attempts (k = 14), and mortality (k = 2), with papers published from 2007-2021. MSH/A was associated with suicide ideation (r ¯ = .14) and attempts (r ¯ = .11, ps < .05). The association of MSH/A and suicide ideation and attempts was higher among women relative to men, those identifying as married versus not married, those actively serving compared to discharged, and those reporting service in the Air Force relative to all other branches. The association of MSH/A with suicide plans and mortality was not calculated due to the small number of studies reporting those effect sizes (ks = 1-2). The effect sizes observed suggest MSH/A is part of a larger network of risk factors for suicide. Moderators indicate that suicide risk is higher among specific groups, and prevention strategies would be most effective if they targeted these individuals. This research area would be strengthened by additional studies of plans and mortality.

Child development in real time: The power of ambulatory assessment for investigating dynamic developmental processes and behavior longitudinally.

Ambulatory assessment methods used to capture "real-world" microprocesses through self-report or passive data collection are used to assess child and adolescent behavior in context. This chapter begins by introducing the researcher to ambulatory assessment methods and describes these methods for use in child and adolescent developmental and behavioral research. Next, the importance of attention to timing is discussed. We then suggest appropriate analytic methods for putting ambulatory assessment data to best use to answer developmental research questions. We end with comments on the ethics of ambulatory assessment data and some concluding remarks for researchers wanting to use these methods in their own work.

Peer Communication about Antisocial Activities as a Mediator of Interparental Conflict in Mid-Adolescence and Externalizing Problems in Late Adolescence.

The current study investigated whether adolescent peer communication about antisocial activities mediates the association between interparental conflict within the family system in mid-adolescence and externalizing problems in late adolescence. Participants were 115 families in which an adolescent and caregiver participated in a longitudinal study. Adolescents (53 girls, 62 boys) completed measures of interparental conflict and externalizing problems in 8th grade (age 14). Afterward, adolescents received a BlackBerry device configured to capture all text messages sent and received. During the 9th grade, four days of text messages were coded for peer communication about antisocial topics. Adolescents again completed a measure of externalizing problems in 11th grade (age 17). Results indicated that interparental conflict in 8th grade correlated positively with adolescents' externalizing problems in 11th grade, but only for girls. In addition, the frequency of communication about antisocial activities mediated the link between interparental conflict and girls' externalizing problems. The findings support the idea that adolescent girls' communications about antisocial activities with their peers may contribute to the link between interparental conflict and girls' externalizing problems.

The antidepressant and anxiolytic effects of cannabinoids in chronic unpredictable stress: a preclinical systematic review and meta-analysis.

Neuroscience research presents contradictory evidence in support of both the protective and destructive effects of cannabinoids in depression. Therefore, this systematic review and meta-analysis summarizes the existing preclinical literature on the effects of cannabinoid administration in the chronic unpredictable stress model of depression in order to evaluate the effects of cannabinoids and identify gaps in the literature. After protocol registration (PROSPERO #CRD42020219986), we systematically searched Scopus, Embase, Psychology & Behavioral Sciences Collection, APA PsychINFO, PubMed, CINAHL Complete, and ProQuest Dissertations & Theses Global from the earliest record of the databases, February 1964, to November 2020 for articles that met inclusion criteria (e.g., rodent subjects and administration of a cannabinoid. A total of 26 articles were included representing a sample size estimate of 1132 rodents with the majority of articles administering daily intraperitoneal injections during chronic unpredictable stress. These articles were evaluated using a modified SYRCLE's risk-of-bias tool. For each continuous behavioral measure, the standardized mean difference was calculated between cannabinoid and vehicle groups in rodents subjected to chronic unpredictable stress. The effects of cannabinoids on depressive-like behavior was evaluated using a multilevel mixed-effects model with effect size weights nested within control groups. Cannabinoid administration moderately improved the pooled negative effects of chronic unpredictable stress on anhedonia, learned helplessness, novelty suppressed feeding, time in the anxiogenic context, and entries into the anxiogenic context. Although the interpretations are limited, these findings suggest that with further investigation, cannabinoids may be a viable long-term treatment for stress-related psychopathologies such as depression.

Acute respiratory failure on a low dose of amiodarone - is it an underdiagnosed and undertreated condition?

Amiodarone-induced pulmonary toxicity (AIPT) has a variety of presentations. Amiodarone use has been rarely associated with the development of acute respiratory failure. We present a patient with a history of paroxysmal atrial fibrillation who developed acute respiratory distress syndrome despite taking a low dose of amiodarone and having no risk or precipitating factors. The diagnosis of AIPT was made after drug discontinuation and exclusion of other potential causes. The development of acute respiratory failure due to AIPT is often underdiagnosed and undertreated. Better identification of risk factors and developing appropriate diagnostic tools for risk stratification of patients receiving amiodarone is mandatory.

Listening In: How Parent-Child Communication Relates to Social and Physical Aggression.

In this study, we investigated the relations between features of parent-child conversations (neutral talk, positive and negative in-dyad and out-dyad talk) and children's social and physical aggression from ages 9-18. Participants were 297 youth (52% girls) of about 9 years old at Time 1 and their parent. Fifty-two percent of this United States sample identified as White, 20% Black, 20% Hispanic, 8% other races/ethnicities. One hundred eighty-seven parents participated in the parent-child observation task. Ninety four percent of parent participants were mothers. Parent-child conversations were observed in the laboratory during preadolescence, and teachers reported child's aggression. Using multinomial logit analyses, we found that coded observations of communication features predicted membership in linear trajectories of social and physical aggression across nine years of adolescence; trajectories were derived via mixture modeling. Parent and child communication characteristics were related to trajectories of aggression that spanned preadolescence and adolescence; however, not all predicted associations were significant. Children's talk about neutral topics predicted being on a lower social aggression trajectory. Positive out-dyad talk from children was related to being on a lower physical aggression trajectory, as was parent in-dyad positive talk. After controlling for other factors, neither parent nor child in- or out-dyad negative talk was associated with social or physical aggression. These findings highlight the importance of positive communication by youth and toward youth in association with long-term social adjustment.

Self-Absorbed and Socially (Network) Engaged: Narcissistic Traits and Social Networking Site Use.

Across two studies, the current research investigated how different dimensions of narcissism (grandiosity/agentic extraversion, entitlement/self-centered antagonism, vulnerability/narcissistic neuroticism) relate to social networking site (SNS) use and behaviors. Study 1 employed a community sample of young adults, whereas Study 2 examined college students. Participants completed assessments of narcissism and SNS use through an online survey. Grandiosity/agentic extraversion was generally associated with greater levels of downward social comparison relative to the other two dimensions. Entitlement/self-centered antagonism generally showed weak correlations with SNS outcomes. Vulnerability/narcissistic neuroticism was generally associated with greater upward social comparison and perceived social exclusion relative to the other two dimensions. Results suggest that SNS experiences may vary depending on the dimensions of narcissism.

Relations between Parent Psychological Control and Parent and Adolescent Social Aggression.

Parent-child interactions and parenting behavior may be related to social aggression among adolescents, and adolescents' social aggression may relate to parents' social aggression. This study investigated (a) whether parent psychological control predicted future adolescent and parent social aggression in their own peer relationships, (b) whether parents' social aggression was related to their use of psychological control within the parent-adolescent relationship (c) whether adolescents' and parents' social aggression was associated with changes in each other's social aggression over time, and (d) change in psychological control. Participants were 174 racially/ethnically diverse parent-adolescent dyads assessed longitudinally for four years. Adolescents were approximately 15-years-old at the first time point. The adolescent sample was 52% girls and 56% identified as White, 22% as Black or African American, 16% as Hispanic, and 5% as mixed race/ ethnicity. Ten percent of the parent participants were fathers. Parents self-reported their psychological control and social aggression, and their adolescents' teachers reported adolescents' social aggression. Hypotheses were tested using longitudinal structural equation modeling and a latent growth curve analysis. The hypothesized effect of parent's psychological control on parent's future aggression with their own peers was supported. Psychological control positively predicted parent aggression from T2 to T3 (ß = .28, p < .05) and from T3 to T4 (ß = .37, p < .05). Other hypotheses were not supported. The findings suggest that the parent-child relationship may influence the parent's functioning in their own peer relationships. Parents' peer relations seem to have important implications for their own wellbeing and the parent-child relationship.

Defending behavior of peer victimization in school and cyber context during childhood and adolescence: A meta-analytic review of individual and peer-relational characteristics.

Adolescent defending of peer victimization in the school and cyber context has received increased attention in developmental science and is an important component of antibullying interventions. However, the overall prevalence, and individual characteristics that correlate with defending in adolescence, have not been systematically and statistically reviewed. Framed in Bronfenbrenner's social-ecological theory, this meta-analytic review included 172 reports out of 155 studies of defending including 150,978 children and adolescent participants from 4 continents (i.e., North America, Europe, Asia, and Australia) to analyze two aspects: (1) the average proportion of defenders in the population and (2) associations between defending and individual and peer-relational correlates of defending in school and cyber contexts. Using mixed-effects modeling, our results confirmed prior findings of gender differences (favoring girls) and age differences (favoring younger children) in defending. We found positive correlations between defending and affective empathy, cognitive empathy, experiences of peer victimization, self-efficacy, popularity, and acceptance, and a negative correlation between defending and moral disengagement. We also found substantial heterogeneity in these effect sizes. The reporter of defending consistently moderated all mean effect sizes. Implications for prevention efforts and future research are discussed. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Experiences with warmth in middle childhood predict features of text-message communication in early adolescence.

This research explored whether experiences with warmth in middle childhood are linked to increased levels of positive affect, decreased levels of negative affect, and decreased levels of disagreeable interactions in text-message communication in adolescence. Participants included 218 children (and their parents and peers) who were on average 10.04-years-old (SD = 0.43) in the 4th grade. In addition to being observed interacting with their parents and friends in the 4th thru 7th grade, participants were provided with BlackBerries configured to capture all incoming and outgoing text-message communication at the end of the 9th, 10th, and 11th grades. Results suggest that observed expressions of warmth are primarily relationship-specific. Further, greater exchanges of warmth within the parent-child and friend-child relationships predicted lower levels of negative affect and duplicity within digital communication. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

When Sharing Is a Bad Idea: The Effects of Online Social Network Engagement and Sharing Passwords with Friends on Cyberbullying Involvement.

Every day, children and adolescents communicate online via social networking sites (SNSs). They also report sharing passwords with peers and friends, a potentially risky behavior in regard to cyber safety. This longitudinal study tested the hypotheses that social network engagement in multiple settings would predict more cyberbullying involvement over time, and that youth who reported sharing passwords would also experience an increase in cyberbullying involvement. Data were collected at two time points one year apart from 1,272 third through eighth grade students. In line with the first study hypothesis, participating in more online SNSs was associated with increased cyberbullying involvement over time, as well as sharing passwords over time. Cyberbullying involvement at T1 predicted decreases in sharing passwords over time, suggesting that youth become aware of the dangers of sharing passwords as a result of their experience. Sharing passwords at T1 was unrelated to cyberbullying involvement at T2. Although it seems that youth may be learning from their previous mistakes, due to the widespread use of social media and normality of sharing passwords among young people, it is important to continue to educate youth about cyber safety and risky online behavior.