Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Germinal Centers.

Victora, Gabriel D; Nussenzweig, Michel C.

Annu Rev Immunol ; 40: 413-442, 2022 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-35113731

2.

Continuous germinal center invasion contributes to the diversity of the immune response.

Hägglöf, Thomas; Cipolla, Melissa; Loewe, Maximilian; Chen, Spencer T; Mesin, Luka; Hartweger, Harald; ElTanbouly, Mohamed A; Cho, Alice; Gazumyan, Anna; Ramos, Victor; Stamatatos, Leonidas; Oliveira, Thiago Y; Nussenzweig, Michel C; Viant, Charlotte.

Cell ; 186(1): 147-161.e15, 2023 01 05.

Artigo em Inglês | MEDLINE | ID: mdl-36565698

3.

The Unreasonable Effectiveness of Reaction Diffusion in Vertebrate Skin Color Patterning.

Milinkovitch, Michel C; Jahanbakhsh, Ebrahim; Zakany, Szabolcs.

Annu Rev Cell Dev Biol ; 39: 145-174, 2023 10 16.

Artigo em Inglês | MEDLINE | ID: mdl-37843926

4.

Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates.

Viant, Charlotte; Weymar, Georg H J; Escolano, Amelia; Chen, Spencer; Hartweger, Harald; Cipolla, Melissa; Gazumyan, Anna; Nussenzweig, Michel C.

Cell ; 183(5): 1298-1311.e11, 2020 11 25.

Artigo em Inglês | MEDLINE | ID: mdl-33125897

5.

Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.

Barnes, Christopher O; West, Anthony P; Huey-Tubman, Kathryn E; Hoffmann, Magnus A G; Sharaf, Naima G; Hoffman, Pauline R; Koranda, Nicholas; Gristick, Harry B; Gaebler, Christian; Muecksch, Frauke; Lorenzi, Julio C Cetrulo; Finkin, Shlomo; Hägglöf, Thomas; Hurley, Arlene; Millard, Katrina G; Weisblum, Yiska; Schmidt, Fabian; Hatziioannou, Theodora; Bieniasz, Paul D; Caskey, Marina; Robbiani, Davide F; Nussenzweig, Michel C; Bjorkman, Pamela J.

Cell ; 182(4): 828-842.e16, 2020 08 20.

Artigo em Inglês | MEDLINE | ID: mdl-32645326

6.

Germinal centers.

Victora, Gabriel D; Nussenzweig, Michel C.

Annu Rev Immunol ; 30: 429-57, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-22224772

7.

Continuous germinal center invasion contributes to the diversity of the immune response.

Hägglöf, Thomas; Cipolla, Melissa; Loewe, Maximilian; Chen, Spencer T; Kara, Ervin E; Mesin, Luka; Hartweger, Harald; ElTanbouly, Mohamed A; Cho, Alice; Gazumyan, Anna; Ramos, Victor; Stamatatos, Leonidas; Oliveira, Thiago Y; Nussenzweig, Michel C; Viant, Charlotte.

Cell ; 2024 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-38657600

8.

B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection.

Chen, Spencer T; Oliveira, Thiago Y; Gazumyan, Anna; Cipolla, Melissa; Nussenzweig, Michel C.

Immunity ; 56(3): 547-561.e7, 2023 03 14.

Artigo em Inglês | MEDLINE | ID: mdl-36882061

9.

Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.

Horwitz, Joshua A; Bar-On, Yotam; Lu, Ching-Lan; Fera, Daniela; Lockhart, Ainsley A K; Lorenzi, Julio C C; Nogueira, Lilian; Golijanin, Jovana; Scheid, Johannes F; Seaman, Michael S; Gazumyan, Anna; Zolla-Pazner, Susan; Nussenzweig, Michel C.

Cell ; 170(4): 637-648.e10, 2017 Aug 10.

Artigo em Inglês | MEDLINE | ID: mdl-28757252

10.

Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.

Robbiani, Davide F; Bozzacco, Leonia; Keeffe, Jennifer R; Khouri, Ricardo; Olsen, Priscilla C; Gazumyan, Anna; Schaefer-Babajew, Dennis; Avila-Rios, Santiago; Nogueira, Lilian; Patel, Roshni; Azzopardi, Stephanie A; Uhl, Lion F K; Saeed, Mohsan; Sevilla-Reyes, Edgar E; Agudelo, Marianna; Yao, Kai-Hui; Golijanin, Jovana; Gristick, Harry B; Lee, Yu E; Hurley, Arlene; Caskey, Marina; Pai, Joy; Oliveira, Thiago; Wunder, Elsio A; Sacramento, Gielson; Nery, Nivison; Orge, Cibele; Costa, Federico; Reis, Mitermayer G; Thomas, Neena M; Eisenreich, Thomas; Weinberger, Daniel M; de Almeida, Antonio R P; West, Anthony P; Rice, Charles M; Bjorkman, Pamela J; Reyes-Teran, Gustavo; Ko, Albert I; MacDonald, Margaret R; Nussenzweig, Michel C.

Cell ; 169(4): 597-609.e11, 2017 May 04.

Artigo em Inglês | MEDLINE | ID: mdl-28475892

11.

Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.

Wang, Zijun; Muecksch, Frauke; Cho, Alice; Gaebler, Christian; Hoffmann, Hans-Heinrich; Ramos, Victor; Zong, Shuai; Cipolla, Melissa; Johnson, Briana; Schmidt, Fabian; DaSilva, Justin; Bednarski, Eva; Ben Tanfous, Tarek; Raspe, Raphael; Yao, Kaihui; Lee, Yu E; Chen, Teresia; Turroja, Martina; Milard, Katrina G; Dizon, Juan; Kaczynska, Anna; Gazumyan, Anna; Oliveira, Thiago Y; Rice, Charles M; Caskey, Marina; Bieniasz, Paul D; Hatziioannou, Theodora; Barnes, Christopher O; Nussenzweig, Michel C.

Immunity ; 55(6): 998-1012.e8, 2022 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-35447092

12.

A New Way to Diversify Antibodies by DNA Transposition.

Robbiani, Davide F; Nussenzweig, Michel C.

Cell ; 164(4): 601-2, 2016 Feb 11.

Artigo em Inglês | MEDLINE | ID: mdl-26871626

13.

Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency.

Bournazos, Stylianos; Gazumyan, Anna; Seaman, Michael S; Nussenzweig, Michel C; Ravetch, Jeffrey V.

Cell ; 165(7): 1609-1620, 2016 Jun 16.

Artigo em Inglês | MEDLINE | ID: mdl-27315478

14.

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.

Escolano, Amelia; Steichen, Jon M; Dosenovic, Pia; Kulp, Daniel W; Golijanin, Jovana; Sok, Devin; Freund, Natalia T; Gitlin, Alexander D; Oliveira, Thiago; Araki, Tatsuya; Lowe, Sarina; Chen, Spencer T; Heinemann, Jennifer; Yao, Kai-Hui; Georgeson, Erik; Saye-Francisco, Karen L; Gazumyan, Anna; Adachi, Yumiko; Kubitz, Michael; Burton, Dennis R; Schief, William R; Nussenzweig, Michel C.

Cell ; 166(6): 1445-1458.e12, 2016 Sep 08.

Artigo em Inglês | MEDLINE | ID: mdl-27610569

15.

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.

Kong, Xiao-Fei; Martinez-Barricarte, Ruben; Kennedy, James; Mele, Federico; Lazarov, Tomi; Deenick, Elissa K; Ma, Cindy S; Breton, Gaëlle; Lucero, Kimberly B; Langlais, David; Bousfiha, Aziz; Aytekin, Caner; Markle, Janet; Trouillet, Céline; Jabot-Hanin, Fabienne; Arlehamn, Cecilia S Lindestam; Rao, Geetha; Picard, Capucine; Lasseau, Théo; Latorre, Daniela; Hambleton, Sophie; Deswarte, Caroline; Itan, Yuval; Abarca, Katia; Moraes-Vasconcelos, Dewton; Ailal, Fatima; Ikinciogullari, Aydan; Dogu, Figen; Benhsaien, Ibtihal; Sette, Alessandro; Abel, Laurent; Boisson-Dupuis, Stéphanie; Schröder, Bernd; Nussenzweig, Michel C; Liu, Kang; Geissmann, Frédéric; Tangye, Stuart G; Gros, Philippe; Sallusto, Federica; Bustamante, Jacinta; Casanova, Jean-Laurent.

Nat Immunol ; 19(9): 973-985, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-30127434

16.

Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.

Muecksch, Frauke; Weisblum, Yiska; Barnes, Christopher O; Schmidt, Fabian; Schaefer-Babajew, Dennis; Wang, Zijun; C Lorenzi, Julio C; Flyak, Andrew I; DeLaitsch, Andrew T; Huey-Tubman, Kathryn E; Hou, Shurong; Schiffer, Celia A; Gaebler, Christian; Da Silva, Justin; Poston, Daniel; Finkin, Shlomo; Cho, Alice; Cipolla, Melissa; Oliveira, Thiago Y; Millard, Katrina G; Ramos, Victor; Gazumyan, Anna; Rutkowska, Magdalena; Caskey, Marina; Nussenzweig, Michel C; Bjorkman, Pamela J; Hatziioannou, Theodora; Bieniasz, Paul D.

Immunity ; 54(8): 1853-1868.e7, 2021 08 10.

Artigo em Inglês | MEDLINE | ID: mdl-34331873

17.

Intra-spike crosslinking overcomes antibody evasion by HIV-1.

Galimidi, Rachel P; Klein, Joshua S; Politzer, Maria S; Bai, Shiyu; Seaman, Michael S; Nussenzweig, Michel C; West, Anthony P; Bjorkman, Pamela J.

Cell ; 160(3): 433-46, 2015 Jan 29.

Artigo em Inglês | MEDLINE | ID: mdl-25635457

18.

Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma.

Robbiani, Davide F; Deroubaix, Stephanie; Feldhahn, Niklas; Oliveira, Thiago Y; Callen, Elsa; Wang, Qiao; Jankovic, Mila; Silva, Israel T; Rommel, Philipp C; Bosque, David; Eisenreich, Tom; Nussenzweig, André; Nussenzweig, Michel C.

Cell ; 162(4): 727-37, 2015 Aug 13.

Artigo em Inglês | MEDLINE | ID: mdl-26276629

19.

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.

Dosenovic, Pia; von Boehmer, Lotta; Escolano, Amelia; Jardine, Joseph; Freund, Natalia T; Gitlin, Alexander D; McGuire, Andrew T; Kulp, Daniel W; Oliveira, Thiago; Scharf, Louise; Pietzsch, John; Gray, Matthew D; Cupo, Albert; van Gils, Marit J; Yao, Kai-Hui; Liu, Cassie; Gazumyan, Anna; Seaman, Michael S; Björkman, Pamela J; Sanders, Rogier W; Moore, John P; Stamatatos, Leonidas; Schief, William R; Nussenzweig, Michel C.

Cell ; 161(7): 1505-15, 2015 Jun 18.

Artigo em Inglês | MEDLINE | ID: mdl-26091035

20.

HIV-1 integration landscape during latent and active infection.

Cohn, Lillian B; Silva, Israel T; Oliveira, Thiago Y; Rosales, Rafael A; Parrish, Erica H; Learn, Gerald H; Hahn, Beatrice H; Czartoski, Julie L; McElrath, M Juliana; Lehmann, Clara; Klein, Florian; Caskey, Marina; Walker, Bruce D; Siliciano, Janet D; Siliciano, Robert F; Jankovic, Mila; Nussenzweig, Michel C.

Cell ; 160(3): 420-32, 2015 Jan 29.

Artigo em Inglês | MEDLINE | ID: mdl-25635456

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Germinal Centers.

Continuous germinal center invasion contributes to the diversity of the immune response.

The Unreasonable Effectiveness of Reaction Diffusion in Vertebrate Skin Color Patterning.

Antibody Affinity Shapes the Choice between Memory and Germinal Center B Cell Fates.

Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.

Germinal centers.

Continuous germinal center invasion contributes to the diversity of the immune response.

B cell receptor signaling in germinal centers prolongs survival and primes B cells for selection.

Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo.

Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.

Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins.

A New Way to Diversify Antibodies by DNA Transposition.

Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency.

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice.

Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency.

Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations.

Intra-spike crosslinking overcomes antibody evasion by HIV-1.

Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma.

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice.

HIV-1 integration landscape during latent and active infection.