Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR.

Yan, Lijun; Mieulet, Virginie; Burgess, Darren; Findlay, Greg M; Sully, Katherine; Procter, Julia; Goris, Jozef; Janssens, Veerle; Morrice, Nick A; Lamb, Richard F.

Mol Cell ; 37(5): 633-42, 2010 Mar 12.

Artigo em Inglês | MEDLINE | ID: mdl-20227368

2.

Glycolysis Dependency as a Hallmark of SF3B1-Mutated Cells.

Vivet-Noguer, Raquel; Tarin, Malcy; Canbezdi, Christine; Dayot, Stephane; Silva, Lisseth; Houy, Alexandre; Martineau, Sylvain; Mieulet, Virginie; Gentric, Géraldine; Loew, Damarys; Lombard, Bérangère; Nemati, Fariba; Richon, Sophie; Guyonnet, Lea; Servois, Vincent; Vagner, Stephan; Stern, Marc-Henri; Roman-Roman, Sergio; Alsafadi, Samar.

Cancers (Basel) ; 14(9)2022 Apr 24.

Artigo em Inglês | MEDLINE | ID: mdl-35565242

3.

Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer.

Mieulet, Virginie; Garnier, Camille; Kieffer, Yann; Guilbert, Thomas; Nemati, Fariba; Marangoni, Elisabetta; Renault, Gilles; Chamming's, Foucauld; Vincent-Salomon, Anne; Mechta-Grigoriou, Fatima.

Sci Rep ; 11(1): 4219, 2021 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-33603134

4.

mTORC2 is the hydrophobic motif kinase for SGK1.

Yan, Lijun; Mieulet, Virginie; Lamb, Richard F.

Biochem J ; 416(3): e19-21, 2008 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-19025518

5.

PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers.

Gentric, Géraldine; Kieffer, Yann; Mieulet, Virginie; Goundiam, Oumou; Bonneau, Claire; Nemati, Fariba; Hurbain, Ilse; Raposo, Graca; Popova, Tatiana; Stern, Marc-Henri; Lallemand-Breitenbach, Valérie; Müller, Sebastian; Cañeque, Tatiana; Rodriguez, Raphaël; Vincent-Salomon, Anne; de Thé, Hugues; Rossignol, Rodrigue; Mechta-Grigoriou, Fatima.

Cell Metab ; 29(1): 156-173.e10, 2019 01 08.

Artigo em Inglês | MEDLINE | ID: mdl-30244973

6.

A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.

Findlay, Greg M; Yan, Lijun; Procter, Julia; Mieulet, Virginie; Lamb, Richard F.

Biochem J ; 403(1): 13-20, 2007 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-17253963

7.

miR200-regulated CXCL12ß promotes fibroblast heterogeneity and immunosuppression in ovarian cancers.

Givel, Anne-Marie; Kieffer, Yann; Scholer-Dahirel, Alix; Sirven, Philemon; Cardon, Melissa; Pelon, Floriane; Magagna, Ilaria; Gentric, Géraldine; Costa, Ana; Bonneau, Claire; Mieulet, Virginie; Vincent-Salomon, Anne; Mechta-Grigoriou, Fatima.

Nat Commun ; 9(1): 1056, 2018 03 13.

Artigo em Inglês | MEDLINE | ID: mdl-29535360

8.

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway.

Pende, Mario; Um, Sung Hee; Mieulet, Virginie; Sticker, Melanie; Goss, Valerie L; Mestan, Jurgen; Mueller, Matthias; Fumagalli, Stefano; Kozma, Sara C; Thomas, George.

Mol Cell Biol ; 24(8): 3112-24, 2004 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-15060135

9.

Heterogeneity in Cancer Metabolism: New Concepts in an Old Field.

Gentric, Géraldine; Mieulet, Virginie; Mechta-Grigoriou, Fatima.

Antioxid Redox Signal ; 26(9): 462-485, 2017 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-27228792

10.

[Arginine and innate immune response]. / Arginine et réponse immunitaire innée: au-delà de la production de monoxyde d'azote.

Mieulet, Virginie; Lamb, Richard F.

Med Sci (Paris) ; 27(5): 461-3, 2011 May.

Artigo em Francês | MEDLINE | ID: mdl-21609661

11.

Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients.

Gruosso, Tina; Mieulet, Virginie; Cardon, Melissa; Bourachot, Brigitte; Kieffer, Yann; Devun, Flavien; Dubois, Thierry; Dutreix, Marie; Vincent-Salomon, Anne; Miller, Kyle Malcolm; Mechta-Grigoriou, Fatima.

EMBO Mol Med ; 8(5): 527-49, 2016 05.

Artigo em Inglês | MEDLINE | ID: mdl-27006338

12.

Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression.

Guillet-Deniau, Isabelle; Mieulet, Virginie; Le Lay, Soazig; Achouri, Younes; Carré, Denis; Girard, Jean; Foufelle, Fabienne; Ferré, Pascal.

Diabetes ; 51(6): 1722-8, 2002 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-12031958

13.

MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas.

Gruosso, Tina; Garnier, Camille; Abelanet, Sophie; Kieffer, Yann; Lemesre, Vincent; Bellanger, Dorine; Bieche, Ivan; Marangoni, Elisabetta; Sastre-Garau, Xavier; Mieulet, Virginie; Mechta-Grigoriou, Fatima.

Nat Commun ; 6: 8583, 2015 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-26456302

14.

Tuberous sclerosis complex: linking cancer to metabolism.

Mieulet, Virginie; Lamb, Richard F.

Trends Mol Med ; 16(7): 329-35, 2010 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-20605525

15.

TPL-2-mediated activation of MAPK downstream of TLR4 signaling is coupled to arginine availability.

Mieulet, Virginie; Yan, Lijun; Choisy, Caroline; Sully, Katherine; Procter, Julia; Kouroumalis, Andreas; Krywawych, Steve; Pende, Mario; Ley, Steven C; Moinard, Christophe; Lamb, Richard F.

Sci Signal ; 3(135): ra61, 2010 Aug 17.

Artigo em Inglês | MEDLINE | ID: mdl-20716763

16.

Shooting the messenger: CULLIN' insulin signaling with Fbw8.

Mieulet, Virginie; Lamb, Richard F.

Dev Cell ; 14(6): 816-7, 2008 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-18539111

17.

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.

Mieulet, Virginie; Roceri, Mila; Espeillac, Catherine; Sotiropoulos, Athanassia; Ohanna, Mickael; Oorschot, Viola; Klumperman, Judith; Sandri, Marco; Pende, Mario.

Am J Physiol Cell Physiol ; 293(2): C712-22, 2007 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-17494629

18.

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.

Shahbazian, David; Roux, Philippe P; Mieulet, Virginie; Cohen, Michael S; Raught, Brian; Taunton, Jack; Hershey, John W B; Blenis, John; Pende, Mario; Sonenberg, Nahum.

EMBO J ; 25(12): 2781-91, 2006 Jun 21.

Artigo em Inglês | MEDLINE | ID: mdl-16763566

19.

Nutrient regulation of mTORC1 and cell growth.

Yan, Lijun; Mieulet, Virginie; Lamb, Richard F.

Cell Cycle ; 9(13): 2473-4, 2010 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-20543582

BVS Doenças Infecciosas e Parasitárias

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar:

PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR.

Glycolysis Dependency as a Hallmark of SF3B1-Mutated Cells.

Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer.

mTORC2 is the hydrophobic motif kinase for SGK1.

PML-Regulated Mitochondrial Metabolism Enhances Chemosensitivity in Human Ovarian Cancers.

A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.

miR200-regulated CXCL12ß promotes fibroblast heterogeneity and immunosuppression in ovarian cancers.

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway.

Heterogeneity in Cancer Metabolism: New Concepts in an Old Field.

[Arginine and innate immune response]. / Arginine et réponse immunitaire innée: au-delà de la production de monoxyde d'azote.

Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients.

Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression.

MAP3K8/TPL-2/COT is a potential predictive marker for MEK inhibitor treatment in high-grade serous ovarian carcinomas.

Tuberous sclerosis complex: linking cancer to metabolism.

TPL-2-mediated activation of MAPK downstream of TLR4 signaling is coupled to arginine availability.

Shooting the messenger: CULLIN' insulin signaling with Fbw8.

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.

Nutrient regulation of mTORC1 and cell growth.