[Effect of hypertrophy of the left ventricle on myocardial perfusion in patients with arterial hypertension]. / Vliianie gipertrofii levogo zheludochka na perfuziiu miokarda u bol'nykh arterial'noi gipertoniei.

A study of 32 patients with arterial hypertension using echocardiography, electrocardiography and myocardial 99mTc-pyrophosphate scintigraphy, demonstrated that developing left-ventricular hypertrophy may interfere with myocardial perfusion. Regression of left-ventricular hypertrophy and recovery of myocardial perfusion is shown to be possible under the effect of antihypertensive treatment.

[State of hemodynamics, function and perfusion of the myocardium in patients with arterial hypertension with different degree of left ventricular hypertrophy]. / Sostoianie gemodinamiki, funktsii i perfuzii miokarda u bol'nykh arterial'noi gipertoniei s razlichnoi stepen'iu gipertrofii levogo zheludochka.

Seventy eight patients with arterial hypertension were examined by echo-, radiocardiography and scintigraphy of the myocardium, using 99mTc pyrophosphate and 201Tl. A relationship was found between the development of hypertrophy of the left ventricle and the impairment of it perfusion and function. At the same time there was a correlation between the decrease in cardiac output and the deterioration of myocardial blood supply. It was demonstrated that 99mTc pyrophosphate or 201Tl myocardial scintigraphy yielded the coincident results when relative heart failure was evaluated in patients with arterial hypertension and left ventricular hypertrophy.

[Changes in cerebral circulation in arterial hypertension]. / Izmeneniia mozgovogo krovotoka pri arterial'noi gipertenzii.

The state of the cerebral blood flow in essential hypertension has been studied in relation to various clinical and hemodynamic parameters. The authors emphasize that the regulation of the cerebral blood flow depends to a great degree on the level of the systolic and pulse pressure as well as on the type of hemodynamics.

[Radionuclide evaluation of the cardiovascular system in arterial hypertension]. / Radionuklidnaia otsenka serdechno-sosudistoi sistemy pri arterial'noi gipertonii.

Proceeding from a study of the nature of changes in hemodynamics during development of hypertensive disease (HD) at its different stages it was shown that hemodynamic changes in 42.1% of the patients with Stage I-IIA HD were of hypertensive type, in the patients with Stage IIB-III HD normal and hypokinetic types of the blood circulation prevailed. After bicycle ergometry exercise the reactivity of the cardiovascular system was revealed more completely. The transition of one hemodynamic type into another and its detection acquired a great importance. The definition of the types of hemodynamics at rest and of effort was very important in terms of adequate antihypertensive therapy and the prediction of a subsequent course of disease. The most complete information on function of the cardiovascular system and myocardial contractility can be obtained with the help of radio-angiocardiography and radionuclide ventriculography. However in the absence of a gamma-chamber radiocardiography can provide necessary information on function of the cardiovascular system in case it is used in one and the same patient over time using bicycle ergometry testing.

[Hemodynamics of pulmonary circulation in hypertension based on data from radionuclide studies]. / Gemodinamika malogo kruga krovoobrashcheniia pri gipertonicheskoi bolezni po dannym radionuklidnykh metodov issledovaniia.

The authors presented the results of a combined radionuclide study of the state of pulmonary hemodynamics in patients with essential hypertension. Altogether 132 patients were investigated. Radiocardiography, perfusion scintigraphy and a study of the regional pulmonary blood flow using radioactive Xe were conducted. An analysis of the results has shown that in some patients pulmonary hypertension develops even at early stages of the disease and is particularly marked in stages IIB-III. The mechanism of development of pulmonary hypertension depended at each stage on the interrelationship and time course of indices that characterized pulmonary circulation, and was of different nature. Hemodynamic disorder was manifested in blood mass redistribution from the lower lung regions to the upper ones, slowing down of rate parameters and a raise of pulmonary vascular resistance.