Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system.

Schenck, Jessica K; Karl, Molly T; Clarkson-Paredes, Cheryl; Bastin, Ashley; Pushkarsky, Tatiana; Brichacek, Beda; Miller, Robert H; Bukrinsky, Michael I.

J Neuroinflammation ; 21(1): 127, 2024 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-38741181

2.

Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.

Hubler, Zita; Allimuthu, Dharmaraja; Bederman, Ilya; Elitt, Matthew S; Madhavan, Mayur; Allan, Kevin C; Shick, H Elizabeth; Garrison, Eric; T Karl, Molly; Factor, Daniel C; Nevin, Zachary S; Sax, Joel L; Thompson, Matthew A; Fedorov, Yuriy; Jin, Jing; Wilson, William K; Giera, Martin; Bracher, Franz; Miller, Robert H; Tesar, Paul J; Adams, Drew J.

Nature ; 560(7718): 372-376, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-30046109

3.

B cell depletion modulates glial responses and enhances blood vessel integrity in a model of multiple sclerosis.

Ahn, Julie J; Islam, Yusra; Clarkson-Paredes, Cheryl; Karl, Molly T; Miller, Robert H.

Neurobiol Dis ; 187: 106290, 2023 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-37709209

4.

Loss of optic nerve oligodendrocytes during maturation alters retinal organization.

Balraj, Annika; Clarkson-Paredes, Cheryl; Miller, Robert H.

Exp Eye Res ; 233: 109540, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37364629

5.

Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis.

Titus, Haley E; Xu, Huan; Robinson, Andrew P; Patel, Priyam A; Chen, Yanan; Fantini, Damiano; Eaton, Valerie; Karl, Molly; Garrison, Eric D; Rose, Indigo V L; Chiang, Ming Yi; Podojil, Joseph R; Balabanov, Roumen; Liddelow, Shane A; Miller, Robert H; Popko, Brian; Miller, Stephen D.

Glia ; 70(10): 1950-1970, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35809238

6.

Induction of myelinating oligodendrocytes in human cortical spheroids.

Madhavan, Mayur; Nevin, Zachary S; Shick, H Elizabeth; Garrison, Eric; Clarkson-Paredes, Cheryl; Karl, Molly; Clayton, Benjamin L L; Factor, Daniel C; Allan, Kevin C; Barbar, Lilianne; Jain, Tanya; Douvaras, Panagiotis; Fossati, Valentina; Miller, Robert H; Tesar, Paul J.

Nat Methods ; 15(9): 700-706, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-30046099

7.

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.

Najm, Fadi J; Madhavan, Mayur; Zaremba, Anita; Shick, Elizabeth; Karl, Robert T; Factor, Daniel C; Miller, Tyler E; Nevin, Zachary S; Kantor, Christopher; Sargent, Alex; Quick, Kevin L; Schlatzer, Daniela M; Tang, Hong; Papoian, Ruben; Brimacombe, Kyle R; Shen, Min; Boxer, Matthew B; Jadhav, Ajit; Robinson, Andrew P; Podojil, Joseph R; Miller, Stephen D; Miller, Robert H; Tesar, Paul J.

Nature ; 522(7555): 216-20, 2015 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-25896324

8.

Targeted Oligodendrocyte Apoptosis in Optic Nerve Leads to Persistent Demyelination.

Pajoohesh-Ganji, Ahdeah; Miller, Robert H.

Neurochem Res ; 45(3): 580-590, 2020 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-30848441

9.

Neurobiology: A change of fate for nerve repair.

Miller, Robert H.

Nature ; 551(7678): 41-42, 2017 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-29094703

10.

The Activators of Cyclin-Dependent Kinase 5 p35 and p39 Are Essential for Oligodendrocyte Maturation, Process Formation, and Myelination.

Luo, Fucheng; Zhang, Jessie; Burke, Kathryn; Miller, Robert H; Yang, Yan.

J Neurosci ; 36(10): 3024-37, 2016 Mar 09.

Artigo em Inglês | MEDLINE | ID: mdl-26961956

11.

Reliability testing of the Larsen and Sharp classifications for rheumatoid arthritis of the elbow.

Jew, Nicholas B; Hollins, Anthony M; Mauck, Benjamin M; Smith, Richard A; Azar, Frederick M; Miller, Robert H; Throckmorton, Thomas W.

J Shoulder Elbow Surg ; 26(1): 140-143, 2017 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-27727050

12.

Apoptosis of Oligodendrocytes during Early Development Delays Myelination and Impairs Subsequent Responses to Demyelination.

Caprariello, Andrew V; Batt, Courtney E; Zippe, Ingrid; Romito-DiGiacomo, Rita R; Karl, Molly; Miller, Robert H.

J Neurosci ; 35(41): 14031-41, 2015 Oct 14.

Artigo em Inglês | MEDLINE | ID: mdl-26468203

13.

Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.

Tilot, Amanda K; Gaugler, Mary K; Yu, Qi; Romigh, Todd; Yu, Wanfeng; Miller, Robert H; Frazier, Thomas W; Eng, Charis.

Hum Mol Genet ; 23(12): 3212-27, 2014 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-24470394

14.

Activated microglia enhance neurogenesis via trypsinogen secretion.

Nikolakopoulou, Angeliki M; Dutta, Ranjan; Chen, Zhihong; Miller, Robert H; Trapp, Bruce D.

Proc Natl Acad Sci U S A ; 110(21): 8714-9, 2013 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-23650361

15.

Cyclin-dependent kinase 5 mediates adult OPC maturation and myelin repair through modulation of Akt and GsK-3ß signaling.

Luo, FuCheng; Burke, Kathryn; Kantor, Christopher; Miller, Robert H; Yang, Yan.

J Neurosci ; 34(31): 10415-29, 2014 Jul 30.

Artigo em Inglês | MEDLINE | ID: mdl-25080600

16.

Signaling through ERK1/2 controls myelin thickness during myelin repair in the adult central nervous system.

Fyffe-Maricich, Sharyl L; Schott, Alexandra; Karl, Molly; Krasno, Janet; Miller, Robert H.

J Neurosci ; 33(47): 18402-8, 2013 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-24259565

17.

Cyclin dependent kinase 5 is required for the normal development of oligodendrocytes and myelin formation.

Yang, Yan; Wang, Haibo; Zhang, Jie; Luo, Fucheng; Herrup, Karl; Bibb, James A; Lu, Richard; Miller, Robert H.

Dev Biol ; 378(2): 94-106, 2013 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-23583582

18.

Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells.

Najm, Fadi J; Zaremba, Anita; Caprariello, Andrew V; Nayak, Shreya; Freundt, Eric C; Scacheri, Peter C; Miller, Robert H; Tesar, Paul J.

Nat Methods ; 8(11): 957-62, 2011 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-21946668

19.

Longitudinal positron emission tomography imaging for monitoring myelin repair in the spinal cord.

Wu, Chunying; Zhu, Junqing; Baeslack, Jonathan; Zaremba, Anita; Hecker, Jordan; Kraso, Janet; Matthews, Paul M; Miller, Robert H; Wang, Yanming.

Ann Neurol ; 74(5): 688-98, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23818306

20.

Accuracy and reliability testing of two methods to measure internal rotation of the glenohumeral joint.

Hall, Justin M; Azar, Frederick M; Miller, Robert H; Smith, Richard; Throckmorton, Thomas W.

J Shoulder Elbow Surg ; 23(9): 1296-300, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-24618193

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