Social, medical and self-perceived factors influencing postpartum screening of diabetes after gestational diabetes.

To assess factors related with postpartum testing for diabetes and the mothers' knowledge about their infant's future risk for diabetes and obesity, we asked 87 women with gestational diabetes who delivered during a 28-month period, to perform a postpartum glucose screening. They were then asked to answer a telephone questionnaire regarding risk perception of diabetes and infant's risk, and were invited to undergo further glucose testing if they missed the first test. Postpartum screening was assessed according to medical, sociodemographic and interview characteristics. A total of 42.5% of women escaped initial postpartum screening and 43.0% escaped secondary testing. Performance of postpartum testing was related with sub-Saharan origin, BMI < 25 kg/m(2) and with high risk perception of developing permanent diabetes. Few women were informed about their infant's future risk.

Does three-dimensional power Doppler ultrasound predict histopathological findings of uterine fibroids? A preliminary study.

OBJECTIVES: To compare three-dimensional (3D) power Doppler sonographic characteristics of fibroids with histopathological parameters. METHODS: We evaluated sonographically 73 fibroids before myomectomy or hysterectomy. For each, the total fibroid volume, a shell of 3 mm and a 1-cm(3) spherical sample from the most vascularized area on subjective assessment were captured. 3D power Doppler vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were generated in the acquired volumes. The degree of cellularity, ischemic necrosis and fibrosclerosis, as well as CD31 and Ki-67 staining for vascular density and proliferation index, respectively, were estimated using the surgical sample. Pathological data were considered as dependent variables and ultrasound data as independent variables in multivariable logistic regression models including patients' characteristics. RESULTS: A high histological 'cellular activity score', combining hypercellularity, a fibrosclerosis rate < 25% and positive Ki-67 staining, was statistically related in multivariate analyses to high 3D power Doppler VI in spherical samples (odds ratio (OR), 1.1 (95% CI, 1.0-1.3), P < 0.05) and VFI (OR, 1.3 (95% CI, 1.0-1.8), P < 0.05). Positive CD31 staining was statistically related to high 3D power Doppler VI in spherical samples (OR, 1.1 (95% CI, 1.0-1.3), P < 0.05). In contrast, ischemic necrosis was statistically related to low 3D power Doppler VI in the total volume (OR, 0.6 (95% CI, 0.4-1.0), P < 0.05) and VFI (OR, 0.4 (95% CI, 0.1-1.1), P < 0.05). CONCLUSION: Vascular density, ischemic necrosis and histological cellular activity score are statistically significantly associated with some 3D power Doppler indices.

An unusual case of congenital cardiac cyst of the interventricular septum.

We present a very rare case of a neonatal multiple haemangiomatosis with a cystic interventricular cardiac haemangioma. An anechoic cyst of 10 mm of diameter, located in the superior third of the interventricular septum was found by foetal echocardiography at 30 weeks of pregnancy. The baby was born at 39 weeks of pregnancy and the skin was covered with multiple purple cutaneous haemangiomas. As neonatal haemangiomatosis may be associated with visceral haemangiomas, the diagnosis of cardiac haemangioma was considered and transthoracic echocardiography revealed a translucent cyst consistent with this diagnosis. At 6 months of age, the cardiac mass was barely visible and most cutaneous lesions had regressed without treatment. Cardiac haemangiomas must be considered in the diagnosis of cystic masses, and the present case emphasizes the tendency towards spontaneous regression of these lesions.