Detalhe da pesquisa
1.
The pentapeptide-repeat protein, MfpA, interacts with mycobacterial DNA gyrase as a DNA T-segment mimic.
Proc Natl Acad Sci U S A
; 118(11)2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33836580
2.
Single-molecule imaging of DNA gyrase activity in living Escherichia coli.
Nucleic Acids Res
; 47(1): 210-220, 2019 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30445553
3.
Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase.
J Antimicrob Chemother
; 75(10): 2835-2842, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728686
4.
Negative supercoiling of DNA by gyrase is inhibited in Salmonella enterica serovar Typhimurium during adaptation to acid stress.
Mol Microbiol
; 107(6): 734-746, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29352745
5.
DNA Gyrase Is the Target for the Quinolone Drug Ciprofloxacin in Arabidopsis thaliana.
J Biol Chem
; 291(7): 3136-44, 2016 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26663076
6.
Quinolone-resistant gyrase mutants demonstrate decreased susceptibility to triclosan.
J Antimicrob Chemother
; 72(10): 2755-2763, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29091182
7.
The naphthoquinone diospyrin is an inhibitor of DNA gyrase with a novel mechanism of action.
J Biol Chem
; 288(7): 5149-56, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23275348
8.
The role of Ca²âº in the activity of Mycobacterium tuberculosis DNA gyrase.
Nucleic Acids Res
; 40(19): 9774-87, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22844097
9.
Use of divalent metal ions in the DNA cleavage reaction of topoisomerase IV.
Nucleic Acids Res
; 39(11): 4808-17, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300644
10.
The dimer state of GyrB is an active form: implications for the initial complex assembly and processive strand passage.
Nucleic Acids Res
; 39(19): 8488-502, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21745817
11.
Vibrio cholerae ParE2 poisons DNA gyrase via a mechanism distinct from other gyrase inhibitors.
J Biol Chem
; 285(51): 40397-408, 2010 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20952390
12.
Structural and biochemical analysis of the pentapeptide repeat protein EfsQnr, a potent DNA gyrase inhibitor.
Antimicrob Agents Chemother
; 55(1): 110-7, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20937785
13.
Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics.
J Antimicrob Chemother
; 66(9): 2061-9, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21693461
14.
Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides.
Nat Commun
; 12(1): 1053, 2021 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33594049
15.
Crystallization and preliminary X-ray analysis of a complex formed between the antibiotic simocyclinone D8 and the DNA breakage-reunion domain of Escherichia coli DNA gyrase.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 65(Pt 8): 846-8, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19652356
16.
Hot-spot consensus of fluoroquinolone-mediated DNA cleavage by Gram-negative and Gram-positive type II DNA topoisomerases.
Nucleic Acids Res
; 35(18): 6075-85, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17766248
17.
DNA gyrase requires DNA for effective two-site coordination of divalent metal ions: further insight into the mechanism of enzyme action.
Biochemistry
; 47(33): 8538-45, 2008 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-18642932
18.
A rapid high-resolution method for resolving DNA topoisomers.
BMC Res Notes
; 11(1): 37, 2018 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29338757
19.
The EU approved antimalarial pyronaridine shows antitubercular activity and synergy with rifampicin, targeting RNA polymerase.
Tuberculosis (Edinb)
; 112: 98-109, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30205975
20.
DNA G-segment bending is not the sole determinant of topology simplification by type II DNA topoisomerases.
Sci Rep
; 4: 6158, 2014 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25142513