Detalhe da pesquisa
1.
Highland games: A benchmarking exercise in predicting biophysical and drug properties of monoclonal antibodies from amino acid sequences.
Biotechnol Bioeng
; 117(7): 2100-2115, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32255523
2.
Machine Learning Models of Antibody-Excipient Preferential Interactions for Use in Computational Formulation Design.
Mol Pharm
; 17(9): 3589-3599, 2020 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32794710
3.
Molecular Computations of Preferential Interaction Coefficients of IgG1 Monoclonal Antibodies with Sorbitol, Sucrose, and Trehalose and the Impact of These Excipients on Aggregation and Viscosity.
Mol Pharm
; 16(8): 3657-3664, 2019 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276620
4.
Understanding the Role of Preferential Exclusion of Sugars and Polyols from Native State IgG1 Monoclonal Antibodies and its Effect on Aggregation and Reversible Self-Association.
Pharm Res
; 36(8): 109, 2019 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127417
5.
Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.
Mol Pharm
; 15(12): 5697-5710, 2018 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30395473
6.
Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies.
MAbs
; 15(1): 2152526, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36476037
7.
Machine learning prediction of antibody aggregation and viscosity for high concentration formulation development of protein therapeutics.
MAbs
; 14(1): 2026208, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35075980
8.
Critical reagents for ligand-binding assays: process development methodologies to enable high-quality reagents.
Bioanalysis
; 14(3): 117-135, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35019733
9.
Molecular computations of preferential interactions of proline, arginine.HCl, and NaCl with IgG1 antibodies and their impact on aggregation and viscosity.
MAbs
; 12(1): 1816312, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938318
10.
An "Fc-Silenced" IgG1 Format With Extended Half-Life Designed for Improved Stability.
J Pharm Sci
; 106(4): 1008-1017, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28057542
11.
Utility of High Throughput Screening Techniques to Predict Stability of Monoclonal Antibody Formulations During Early Stage Development.
J Pharm Sci
; 106(8): 1971-1977, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28456733
12.
Computational tool for the early screening of monoclonal antibodies for their viscosities.
MAbs
; 8(1): 43-8, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26399600