Detalhe da pesquisa
1.
Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice.
iScience
; 26(8): 107375, 2023 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37599829
2.
SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA.
J Neurosci
; 31(48): 17425-36, 2011 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22131404
3.
An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.
J Biol Chem
; 285(46): 35567-77, 2010 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20826791
4.
Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy.
Hum Mol Genet
; 18(11): 1937-50, 2009 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19279159
5.
The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms.
Front Mol Neurosci
; 10: 159, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28596723
6.
Renal ischemia and reperfusion activates the eIF 2 alpha kinase PERK.
Biochim Biophys Acta
; 1741(3): 314-24, 2005 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15936177
7.
PERK is activated differentially in peripheral organs following cardiac arrest and resuscitation.
Resuscitation
; 66(3): 379-89, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16029920
8.
Identification of novel polyglutamine-expanded aggregation species in spinal and bulbar muscular atrophy.
Brain Res
; 1628(Pt B): 254-264, 2015 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26453288
9.
Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease.
J Clin Invest
; 125(2): 831-45, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25607844
10.
Autophagy and access: understanding the role of androgen receptor subcellular localization in SBMA.
Autophagy
; 5(8): 1194-7, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19770590
11.
The cell and molecular biology of neurodegenerative diseases: an overview.
Front Neurol
; 4: 194, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24348458
12.
Cerebral ischemia and the unfolded protein response.
J Neurochem
; 91(1): 1-8, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15379881