Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Systematic Analysis of Clemastine, a Candidate Apicomplexan Parasite-Selective Tubulin-Targeting Agent.

Abbaali, Izra; Truong, Danny A; Day, Shania D; Haro-Ramirez, Nancy; Morrissette, Naomi S.

Int J Mol Sci ; 23(1)2021 Dec 22.

Artigo em Inglês | MEDLINE | ID: mdl-35008492

2.

From B to A: making an essential cofactor in a human parasite.

Morrissette, Naomi S; Goulding, Celia W.

Biochem J ; 474(18): 3089-3092, 2017 08 30.

Artigo em Inglês | MEDLINE | ID: mdl-28860337

3.

MEC-17 is an alpha-tubulin acetyltransferase.

Akella, Jyothi S; Wloga, Dorota; Kim, Jihyun; Starostina, Natalia G; Lyons-Abbott, Sally; Morrissette, Naomi S; Dougan, Scott T; Kipreos, Edward T; Gaertig, Jacek.

Nature ; 467(7312): 218-22, 2010 Sep 09.

Artigo em Inglês | MEDLINE | ID: mdl-20829795

4.

Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella.

Francia, Maria E; Jordan, Carly N; Patel, Jay D; Sheiner, Lilach; Demerly, Jessica L; Fellows, Justin D; de Leon, Jessica Cruz; Morrissette, Naomi S; Dubremetz, Jean-François; Striepen, Boris.

PLoS Biol ; 10(12): e1001444, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-23239939

5.

Diaryl and heteroaryl sulfides: synthesis via sulfenyl chlorides and evaluation as selective anti-breast-cancer agents.

Yonova, Ivelina M; Osborne, Charlotte A; Morrissette, Naomi S; Jarvo, Elizabeth R.

J Org Chem ; 79(5): 1947-53, 2014 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-24564865

6.

A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components.

de Leon, Jessica Cruz; Scheumann, Nicole; Beatty, Wandy; Beck, Josh R; Tran, Johnson Q; Yau, Candace; Bradley, Peter J; Gull, Keith; Wickstead, Bill; Morrissette, Naomi S.

Eukaryot Cell ; 12(7): 1009-19, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23687115

7.

Stereospecific nickel-catalyzed cross-coupling reactions of alkyl Grignard reagents and identification of selective anti-breast-cancer agents.

Yonova, Ivelina M; Johnson, A George; Osborne, Charlotte A; Moore, Curtis E; Morrissette, Naomi S; Jarvo, Elizabeth R.

Angew Chem Int Ed Engl ; 53(9): 2422-2427, 2014 Feb 24.

Artigo em Inglês | MEDLINE | ID: mdl-24478275

8.

Toxoplasma replication is inhibited by MMV676477 without development of resistance.

Abbaali, Izra; Truong, Danny; Wetzel, Dawn M; Morrissette, Naomi S.

Cytoskeleton (Hoboken) ; 2024 May 16.

Artigo em Inglês | MEDLINE | ID: mdl-38757481

9.

SPM1 stabilizes subpellicular microtubules in Toxoplasma gondii.

Tran, Johnson Q; Li, Catherine; Chyan, Alice; Chung, Lawton; Morrissette, Naomi S.

Eukaryot Cell ; 11(2): 206-16, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-22021240

10.

The tubulin database: Linking mutations, modifications, ligands and local interactions.

Abbaali, Izra; Truong, Danny; Day, Shania Deon; Mushayeed, Faliha; Ganesh, Bhargavi; Haro-Ramirez, Nancy; Isles, Juliet; Nag, Hindol; Pham, Catherine; Shah, Priya; Tomar, Ishaan; Manel-Romero, Carolina; Morrissette, Naomi S.

PLoS One ; 18(12): e0295279, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-38064432

11.

A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division.

Beck, Josh R; Rodriguez-Fernandez, Imilce A; de Leon, Jessica Cruz; Huynh, My-Hang; Carruthers, Vern B; Morrissette, Naomi S; Bradley, Peter J.

PLoS Pathog ; 6(9): e1001094, 2010 Sep 09.

Artigo em Inglês | MEDLINE | ID: mdl-20844581

12.

Host cell invasion by Toxoplasma gondii is temporally regulated by the host microtubule cytoskeleton.

Sweeney, Kristin R; Morrissette, Naomi S; LaChapelle, Stephanie; Blader, Ira J.

Eukaryot Cell ; 9(11): 1680-9, 2010 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-20435700

13.

α-Tubulin mutations alter oryzalin affinity and microtubule assembly properties to confer dinitroaniline resistance.

Lyons-Abbott, Sally; Sackett, Dan L; Wloga, Dorota; Gaertig, Jacek; Morgan, Rachel E; Werbovetz, Karl A; Morrissette, Naomi S.

Eukaryot Cell ; 9(12): 1825-34, 2010 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-20870876

14.

FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells.

Bell, Bryan D; Leverrier, Sabrina; Weist, Brian M; Newton, Ryan H; Arechiga, Adrian F; Luhrs, Keith A; Morrissette, Naomi S; Walsh, Craig M.

Proc Natl Acad Sci U S A ; 105(43): 16677-82, 2008 Oct 28.

Artigo em Inglês | MEDLINE | ID: mdl-18946037

15.

Auranofin Resistance in Toxoplasma gondii Decreases the Accumulation of Reactive Oxygen Species but Does Not Target Parasite Thioredoxin Reductase.

Ma, Christopher I; Tirtorahardjo, James A; Jan, Sharon; Schweizer, Sakura S; Rosario, Shawn A C; Du, Yanmiao; Zhang, Jerry J; Morrissette, Naomi S; Andrade, Rosa M.

Front Cell Infect Microbiol ; 11: 618994, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33816332

16.

Mutations in alpha-tubulin confer dinitroaniline resistance at a cost to microtubule function.

Ma, Christopher; Li, Catherine; Ganesan, Lakshmi; Oak, Jean; Tsai, Susan; Sept, David; Morrissette, Naomi S.

Mol Biol Cell ; 18(12): 4711-20, 2007 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-17881728

17.

The cell-penetrating peptide, Pep-1, has activity against intracellular chlamydial growth but not extracellular forms of Chlamydia trachomatis.

Park, Narae; Yamanaka, Kinrin; Tran, Dat; Chandrangsu, Pete; Akers, Johnny C; de Leon, Jessica C; Morrissette, Naomi S; Selsted, Michael E; Tan, Ming.

J Antimicrob Chemother ; 63(1): 115-23, 2009 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-18957395

18.

The tubulin mutation database: A resource for the cytoskeleton community.

Pham, Catherine L; Morrissette, Naomi S.

Cytoskeleton (Hoboken) ; 76(2): 186-191, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30667171

19.

Cytoskeleton of apicomplexan parasites.

Morrissette, Naomi S; Sibley, L David.

Microbiol Mol Biol Rev ; 66(1): 21-38; table of contents, 2002 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-11875126

20.

Dinitroanilines bind alpha-tubulin to disrupt microtubules.

Morrissette, Naomi S; Mitra, Arpita; Sept, David; Sibley, L David.

Mol Biol Cell ; 15(4): 1960-8, 2004 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-14742718

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